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Identification of non-amplified DNA sequences and single-base mutations is essential for molecular biology and genetic diagnostics. This paper reports a novel sensor consisting of electrochemically-gated graphene coplanar waveguides coupled…

We develop a theory of turbulence of weak random gravity waves on surface of deep water in which the main nonlinear process at high-frequency part of the spectrum is a nonlocal interaction with a strong low-frequency component. The latter…

Fluid Dynamics · Physics 2024-09-05 A. O. Korotkevich , S. V. Nazarenko , Y. Pan , J. Shatah

We report in situ single-molecule measurements of proton-induced double-strand breaks (DSBs) in DNA immersed in water, using real-time fluorescence tracking along the entire proton path, including the Bragg peak region. By chemically…

Biological Physics · Physics 2025-10-03 R. Liénard , P. Barberet , K. Chatzipapas , G. Devès , T. Dhôte , T. Guérin , H. Seznec , F. Gobet

The attenuation of phonon modes of the DNA is due to the exchange of water molecules adsorbed by a molecule of DNA and the bulk solvent. Using Maxwell's mechanism of relaxation and a simple lattice model of the DNA, we show that the…

Soft Condensed Matter · Physics 2011-11-03 V. L. Golo

The notion that large electric fields at the air-water interface catalyze spontaneous chemical reactions has sparked significant debate, with far reaching implications for atmospheric chemistry and interfacial reactivity. Using vibrational…

Several studies suggest strong correlation between different types of cancer and the relative concentration of short circulating RNA sequences (miRNA). Because of short length and low concentration, miRNA detection is not easy. Standard…

Mesoscale and Nanoscale Physics · Physics 2021-10-25 Luyan Yang , Christophe Cullin , Juan Elezgaray

The mechanism behind mutual recognition of homologous DNA sequences prior to genetic recombination is one of the remaining puzzles in molecular biology. Leading models of homology recognition, based on classical electrostatics, neglect the…

Biological Physics · Physics 2024-08-26 Ehud Haimov , Jonathan G. Hedley , Alexei A. Kornyshev

When multivalent salts are added to dilute DNA solution, the DNA chains condense into bundles of a well-defined size. We explore two physical problems motivated by this phenomenon: the origin of the attractive interactions between the…

Soft Condensed Matter · Physics 2007-05-23 Bae-Yeun Ha , Andrea J. Liu

The osmotic coefficient of B-DNA in water may, in moderately dilute solutions, deviate as much as 100 % from predictions based on a simple 'counterion condensation' theory. We determine the results for osmotic properties via a cell model…

Soft Condensed Matter · Physics 2019-05-15 Per Lyngs Hansen , Rudi Podgornik , V. Adrian Parsegian

The morphology of DNA is strongly influenced by its surrounding environment, including factors such as pH, salt type and valency, and the presence of polymers. Inorganic salts are known to reduce the DNA chain length through mechanisms like…

Soft Condensed Matter · Physics 2026-03-03 Anuj Chhabra , Sandip Mandal , Yugang Zhang , Oleg Gang , Prabal K. Maiti , Sunita Srivastava

The detection of single molecules has facilitated many advances in life- and material-sciences. Commonly, it founds on the fluorescence detection of single molecules, which are for example attached to the structures under study. For…

The phase diagram of a water solution of DNA and oppositely charged spherical macroions is studied. DNA winds around spheres to form beads-on-a-string complexes resembling the chromatin 10 nm fiber. At small enough concentration of spheres…

Soft Condensed Matter · Physics 2009-11-07 Toan T. Nguyen , Boris I. Shklovskii

We present a short review of various experiments that measure charge transfer and charge transport in DNA. Some general comments are made on the possible connection between 'chemistry-style' charge transfer experiments that probe…

Disordered Systems and Neural Networks · Physics 2009-11-10 N. P. Armitage , M. Briman , G. Gruner

Observations of powerful radio waves from neutron star magnetospheres raise the question of how strong waves interact with particles in a strong background magnetic field $B_{bg}$. This problem is examined by solving the particle motion in…

High Energy Astrophysical Phenomena · Physics 2022-07-13 Andrei M. Beloborodov

We study statistical properties of DNA chains of thirteen microbial complete genomes. We find that the power spectrum of several of the sequences studied flattens off in the low frequency limit. This implies that the correlation length in…

Statistical Mechanics · Physics 2009-10-31 Maria de Sousa Vieira

Owing to its longevity and enormous information density, DNA, the molecule encoding biological information, has emerged as a promising archival storage medium. However, due to technological constraints, data can only be written onto many…

Emerging Technologies · Computer Science 2018-03-12 Reinhard Heckel , Gediminas Mikutis , Robert N. Grass

This paper introduces the use of cable dynamics models as a means to explore the mechanics of DNA on long-length scales. It is on these length scales that DNA forms twisted and curved three-dimensional shapes known as supercoils and loops.…

Biological Physics · Physics 2007-05-23 Sachin Goyal , Todd Lillian , Noel C. Perkins , Edgar Meyhofer

The structure of DNA Binding Proteins enables a strong interaction with their specific target site on DNA. However, recent single molecule experiment reported that proteins can diffuse on DNA. This suggests that the interactions between…

Biomolecules · Quantitative Biology 2015-05-13 Vincent Dahirel , Fabien Paillusson , Marie Jardat , Maria Barbi , Jean-Marc Victor

Quantum dots are frequently used as charge sensitive devices in low temperature experiments to probe electric charge in mesoscopic conductors where the current running through the quantum dot is modulated by the nearby charge environment.…

Mesoscale and Nanoscale Physics · Physics 2024-01-12 Harald Havir , Subhomoy Haldar , Waqar Khan , Sebastian Lehmann , Kimberly A. Dick , Claes Thelander , Peter Samuelsson , Ville F. Maisi

Based on our formulation of the DNA electrophoresis near a pore [P. Rowghanian and A. Y. Grosberg, Phys. Rev. E 87, 042723 (2013)], we address the electrophoretic DNA capture into a nanopore as a steady-state process of particle absorption…

Biological Physics · Physics 2013-06-20 Payam Rowghanian , Alexander Y. Grosberg
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