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We consider in this paper a general SEIRS model describing the dynamics of an infectious disease including latency, waning immunity and infection-induced mortality. We derive an infinite system of differential equations that provides an…

Optimization and Control · Mathematics 2022-01-26 Marcel Fang , Pierre-Alexandre Bliman

The paper describes and compares three approaches to modeling an epidemic spread. The first approach is a well-known system of SIR ordinary differential equations. The second is a mean-field model, in which an isolation strategy for each…

Populations and Evolution · Quantitative Biology 2024-11-06 Viktoriya Petrakova , Olga Krivorotko

We study the long-time behavior of solutions of the SIRS model, a reaction-diffusion system that appears in epidemiology to describe the spread of epidemics. We allow the system to be heterogeneous periodic. Under some hypotheses on the…

Analysis of PDEs · Mathematics 2024-02-02 Romain Ducasse , Maxime Laborde

In this paper, an SIR epidemic model with variable size of population is considered. We study optimal control problem for an SIR model with "vaccination" and "treatment" as controls. It is shown that an optimal control exists. We have…

Optimization and Control · Mathematics 2016-12-28 Olga Klimenkova

This paper is devoted to the study of an age-structured SIRS epidemic model, in which a population affected by a disease is divided into susceptible, infected, and removed individuals. We assume that the force of infection may be nonlinear…

Analysis of PDEs · Mathematics 2026-03-16 Luisa Malaguti , Stefania Perrotta

We consider the SEIRS compartment epidemiology model suitable for predicting the evolution of the COVID-19 pandemy in the extreme limiting case of no acquired immunity. The disease-free and endemic fixed points are found and their stability…

Populations and Evolution · Quantitative Biology 2020-12-15 J. M. Ilnytskyi

The paradigm for compartment models in epidemiology assumes exponentially distributed incubation and removal times, which is not realistic in actual populations. Commonly used variations with multiple exponentially distributed variables are…

Populations and Evolution · Quantitative Biology 2021-02-10 P. Hernández , C. Pena , A. Ramos , J. J. Gómez-Cadenas

For a non-autonomous SEIRS model with general incidence, that admits [T. Kuniya and Y. Nakata, Permanence and extinction for a nonautonomous SEIRS epidemic model, Appl. Math. Computing 218, 9321-9331 (2012)] as a very particular case, we…

Dynamical Systems · Mathematics 2013-11-14 Joaquim P. Mateus , César M. Silva

The dramatic outbreak of the coronavirus disease 2019 (COVID-19) pandemics and its ongoing progression boosted the scientific community's interest in epidemic modeling and forecasting. The SIR (Susceptible-Infected-Removed) model is a…

Populations and Evolution · Quantitative Biology 2021-02-24 Dimiter Prodanov

In this paper, we give a complete analysis of an SIS epidemiological model in a population of varying size with two dissimilar groups of infective individuals. It is mainly based on the discussion of the existence and stability of…

Classical Analysis and ODEs · Mathematics 2007-05-23 M. R. Razvan

We study the dynamics of a spatially structured model of worldwide epidemics and formulate predictions for arrival times of the disease at any city in the network. The model is comprised of a system of ordinary differential equations…

Pattern Formation and Solitons · Physics 2018-02-14 Lawrence M. Chen , Matt Holzer , Anne Shapiro

This article is devoted to the analysis of a particle system model for epidemics among a finite population with susceptible, infective and removed individuals (SIR). The infection mechanism depends on the relative distance between…

Probability · Mathematics 2020-03-10 Monia Capanna

We study the problem of optimal control of the stochastic SIR model. Models of this type are used in mathematical epidemiology to capture the time evolution of highly infectious diseases such as COVID-19. Our approach relies on…

Populations and Evolution · Quantitative Biology 2020-05-04 Andrew Lesniewski

Containment of epidemic outbreaks entails great societal and economic costs. Cost-effective containment strategies rely on efficiently identifying infected individuals, making the best possible use of the available testing resources.…

Populations and Evolution · Quantitative Biology 2020-12-01 Laura Natali , Saga Helgadottir , Onofrio M. Marago , Giovanni Volpe

Given maximal social distancing duration and intensity, how can one minimize the epidemic final size, or equivalently the total number of individuals infected during the outbreak? A complete answer to this question is provided and…

Optimization and Control · Mathematics 2020-10-01 Pierre-Alexandre Bliman , Michel Duprez

The Susceptible-Infected-Recovered (SIR) epidemic model is extensively used for the study of the spread of infectious diseases. Even that the exact solution of the model can be obtained in an exact parametric form, in order to perform the…

Populations and Evolution · Quantitative Biology 2020-06-17 Tiberiu Harko , Man Kwong Mak

We present a class of SEIR Markov chain models for infectious diseases observed over discrete time in a random human population living in a closed environment. The population changes over time through random births, deaths, and transitions…

Populations and Evolution · Quantitative Biology 2019-07-30 Divine Wanduku , Chinmoy Rahul

In this work, we study global existence, boundedness and convergence of nonnegative classical solutions of a Neumann initial-boundary value problem for a cross diffusive SIS (susceptible-infected-susceptible) epidemic model with power-like…

Analysis of PDEs · Mathematics 2022-08-23 Huicong Li , Tian Xiang

Compartmental models are widely used in mathematical epidemiology to describe dynamics of infection disease. A new SIS-PDE model, recently derived by Chalub and Souza, is based on a diffusion-drift approximation of probability density in a…

Analysis of PDEs · Mathematics 2022-07-26 Marina Chugunova , Roman Taranets , Nataliya Vasylyeva

We present and compare two different optimal control approaches applied to SEIR models in epidemiology, which allow us to obtain some policies for controlling the spread of an epidemic. The first approach uses Dynamic Programming to…

Optimization and Control · Mathematics 2024-05-06 Simone Cacace , Alessio Oliviero