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Synchronized oscillations in networks of inhibitory and excitatory coupled bursting neurons are common in a variety of neural systems from central pattern generators to human brain circuits. One example of the latter is the subcortical…

Neurons and Cognition · Quantitative Biology 2011-09-21 Choongseok Park , Leonid L. Rubchinsky

Recent experiments have shown that the spontaneous activity of young dissociated neuronal cultures can be described as a process of highly inhomogeneous nucleation and front propagation due to the localization of noise activity, i.e., noise…

Neurons and Cognition · Quantitative Biology 2021-05-26 Javier G. Orlandi , Jaume Casademunt

Noise-induced population bursting has been widely identified to play important roles in the information process. We constructed a mathematical model for a random and sparse neural network where bursting can be induced from the resting state…

Neurons and Cognition · Quantitative Biology 2021-09-10 Na Yu , Gurpreet Jagdev , Michelle Morgovsky

This paper proposes a neuronal circuitry layout and synaptic plasticity principles that allow the (pyramidal) neuron to act as a "combinatorial switch". Namely, the neuron learns to be more prone to generate spikes given those combinations…

Biological Physics · Physics 2017-05-09 Marat M. Rvachev

Bursting is a phenomenon found in a variety of physical and biological systems. For example, in neuroscience, bursting is believed to play a key role in the way information is transferred in the nervous system. In this work, we propose a…

Neurons and Cognition · Quantitative Biology 2016-05-31 Maria Luisa Saggio , Andreas Spiegler , Christophe Bernard , Viktor K. Jirsa

We report a detailed analysis on the emergence of bursting in a recently developed neural mass model that takes short-term synaptic plasticity into account. The one being used here is particularly important, as it represents an exact…

Dynamical Systems · Mathematics 2021-09-15 Halgurd Taher , Daniele Avitabile , Mathieu Desroches

Living neuronal networks in dissociated neuronal cultures are widely known for their ability to generate highly robust spatiotemporal activity patterns in various experimental conditions. These include neuronal avalanches satisfying the…

Adaptation and Self-Organizing Systems · Physics 2022-05-17 I. Y. Tyukin , D. Iudin , F. Iudin , T. Tyukina , V. Kazantsev , I. Mukhina , A. N. Gorban

The importance of self-feedback autaptic transmission in modulating spike-time irregularity is still poorly understood. By using a biophysical model that incorporates autaptic coupling, we here show that self-innervation of neurons…

Neurons and Cognition · Quantitative Biology 2016-07-04 Daqing Guo , Shengdun Wu , Mingming Chen , Matjaz Perc , Yangsong Zhang , Jingling Ma , Yan Cui , Peng Xu , Yang Xia , Dezhong Yao

Strong inhibitory input to neurons, which occurs in balanced states of neural networks, increases synaptic current fluctuations. This has led to the assumption that inhibition contributes to the high spike-firing irregularity observed in…

Neurons and Cognition · Quantitative Biology 2021-02-19 Tomas Barta , Lubomir Kostal

Neurons fire irregularly on multiple timescales when stimulated with a periodic pulse train. This raises two questions: Does this irregularity imply significant intrinsic stochasticity? Can existing neuron models be readily extended to…

Cell Behavior · Quantitative Biology 2013-01-14 Daniel Soudry , Ron Meir

Dynamical balance of excitation and inhibition is usually invoked to explain the irregular low firing activity observed in the cortex. We propose a robust nonlinear balancing mechanism for a random network of spiking neurons, which works…

Disordered Systems and Neural Networks · Physics 2025-05-29 Antonio Politi , Alessandro Torcini

Long-time series of neuronal recordings are resulting from the activity of connected neuronal networks. Yet how neuronal properties can be extracted remains empirical. We review here the data analysis based on network models to recover…

Neurons and Cognition · Quantitative Biology 2024-11-04 Lou Zonca , Elena Dossi , Nathalie Rouach , D. Holcman

In the absence of inhibition, excitatory neuronal networks can alternate between bursts and interburst intervals (IBI), with heterogeneous length distributions. As this dynamic remains unclear, especially the durations of each epoch, we…

Neurons and Cognition · Quantitative Biology 2020-12-17 Lou Zonca , David Holcman

Neuromorphic computing using spike-based learning has broad prospects in reducing computing power. Memristive neurons composed with two locally active memristors have been used to mimic the dynamical behaviors of biological neurons. In this…

Emerging Technologies · Computer Science 2020-04-14 Yeheng Bo , Peng Zhang , Ziqing Luo , Shuai Li , Juan Song , Xinjun Liu

Neuronal cells present periodic trains of localized voltage spikes involving a large amount of different ionic channels. A relevant question is whether this is a cooperative effect or it could also be an intrinsic property of individual…

Biological Physics · Physics 2018-04-17 Laureano Ramírez-Piscina , José M. Sancho

Bursting oscillations are commonly seen as a mechanism for information coding in neuroscience and have also been observed in many physical, biochemical, and chemical systems. This study focuses on the computational investigation of…

Dynamical Systems · Mathematics 2021-10-15 Na Yu , Xuan Xia , Juan Liyau

Various classes of neurons alternate between high-frequency discharges and silent intervals. This phenomenon is called burst firing. To analyze burst activity in an insect system, grasshopper auditory receptor neurons were recorded in vivo…

Neurons and Cognition · Quantitative Biology 2008-07-17 Hugo G. Eyherabide , Ariel Rokem , Andreas V. M. Herz , Ines Samengo

We study an excitable active rotator with slowly adapting nonlinear feedback and noise. Depending on the adaptation and the noise level, this system may display noise-induced spiking, noise-perturbed oscillations, or stochastic busting. We…

Adaptation and Self-Organizing Systems · Physics 2020-08-26 Igor Franović , Serhiy Yanchuk , Sebastian Eydam , Iva Bačić , Matthias Wolfrum

Neural oscillations are universal phenomena and can be observed at different levels of neural systems, from single neuron to macroscopic brain. The frequency of those oscillations are related to the brain functions. However, little is know…

Neurons and Cognition · Quantitative Biology 2015-07-30 Lianchun Yu , Longfei Wang , Fei Jia , Duojie Jia

Noise induced excitability is studied in type I and II Morris-Lecar neurons subject to constant sub threshold input, where fluctuations arise from sodium and potassium ion channels. Ion channels open and close randomly, creating current…

Cell Behavior · Quantitative Biology 2014-09-08 Jay Newby