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The transfer of the medical care services to the patient, rather than the transport of the patient to the medical services providers is aim of the project. This is achieved by using web-based applications including Modern Medical…

Computers and Society · Computer Science 2014-03-13 Hafez Fouad

This is a thought piece on data-intensive science requirements for databases and science centers. It argues that peta-scale datasets will be housed by science centers that provide substantial storage and processing for scientists who access…

Databases · Computer Science 2007-05-23 Jim Gray , David T. Liu , Maria Nieto-Santisteban , Alexander S. Szalay , David DeWitt , Gerd Heber

Many of the current scientific advances in the life sciences have their origin in the intensive use of data for knowledge discovery. In no area this is so clear as in bioinformatics, led by technological breakthroughs in data acquisition…

Machine Learning · Computer Science 2018-02-28 Davide Bacciu , Paulo J. G. Lisboa , José D. Martín , Ruxandra Stoean , Alfredo Vellido

The storage and manipulation of digital images and the analysis of the information held in those images are essential requirements for next-generation medical information systems. The medical community has been exploring collaborative…

Databases · Computer Science 2007-05-23 D Rogulin , F Estrella , T Hauer , R McClatchey , T Solomonides

Increasingly sophisticated experiments, coupled with large-scale computational models, have the potential to systematically test biological hypotheses to drive our understanding of multicellular systems. In this short review, we explore key…

Quantitative Methods · Quantitative Biology 2019-10-28 Paul Macklin

Biomedical research increasingly relies on heterogeneous, high-dimensional datasets, yet effective visualization remains hindered by fragmented code resources, steep programming barriers, and limited domain-specific guidance. Bizard is an…

The number of biomedical research articles published has doubled in the past 20 years. Search engine based systems naturally center around searching, but researchers may not have a clear goal in mind, or the goal may be expressed in a query…

Digital Libraries · Computer Science 2017-10-25 Jessica Perrie , Yanqi Hao , Zack Hayat , Recep Colak , Kelly Lyons , Shankar Vembu , Sam Molyneux

Over the past few years, a growing number of data platforms have emerged, including data commons, data repositories, and databases containing biomedical, environmental, social determinants of health and other data relevant to improving…

Science is a social process with far-reaching impact on our modern society. In the recent years, for the first time we are able to scientifically study the science itself. This is enabled by massive amounts of data on scientific…

Digital Libraries · Computer Science 2015-05-21 Lovro Šubelj , Marko Bajec , Biljana Mileva Boshkoska , Andrej Kastrin , Zoran Levnajić

Nuanced cancer patient care is needed, as the development and clinical course of cancer is multifactorial with influences from the general health status of the patient, germline and neoplastic mutations, co-morbidities, and environment. To…

Quantitative Methods · Quantitative Biology 2023-09-26 Ali Firooz , Avery T. Funkhouser , Julie C. Martin , W. Jeffery Edenfield , Homayoun Valafar , Anna V. Blenda

Data commons collate data with cloud computing infrastructure and commonly used software services, tools and applications to create biomedical resources for the large-scale management, analysis, harmonization, and sharing of biomedical…

Genomics · Quantitative Biology 2018-12-27 Robert L. Grossman

The vision of IASIS project is to turn the wave of big biomedical data heading our way into actionable knowledge for decision makers. This is achieved by integrating data from disparate sources, including genomics, electronic health records…

Since the advent of next-generation sequencing in the early 2000s, the volume of bioinformatics software tools and databases has exploded and continues to grow rapidly. Documenting this evolution on a global and time-dependent scale is a…

Motivation: Bioinformatics is faced with a variety of problems that require human involvement. Tasks like genome annotation, image analysis, knowledge-base construction and protein structure determination all benefit from human input. In…

Quantitative Methods · Quantitative Biology 2013-07-01 Benjamin M. Good , Andrew I. Su

This paper introduces a novel toolbox named BIDEAL for the generation of biclusters, their analysis, visualization, and validation. The objective is to facilitate researchers to use forefront biclustering algorithms embedded on a single…

Other Computer Science · Computer Science 2020-07-29 Nishchal K. Verma , T. Sharma , S. Dixit , P. Agrawal , S. Sengupta , V. Singh

Personalised medicine strives to identify the right treatment for the right patient at the right time, integrating different types of biological and environmental information. Such information come from a variety of sources: omics data…

Applications · Statistics 2014-01-14 Marco Scutari

Scientists increasingly recognize the importance of providing rich, standards-adherent metadata to describe their experimental results. Despite the availability of sophisticated tools to assist in the process of data annotation,…

The integration of bioinformatics predictions and experimental validation plays a pivotal role in advancing biological research, from understanding molecular mechanisms to developing therapeutic strategies. Bioinformatics tools and methods…

XML data warehouses form an interesting basis for decision-support applications that exploit complex data. However, native-XML database management systems (DBMSs) currently bear limited performances and it is necessary to research for ways…

Databases · Computer Science 2017-01-30 Hadj Mahboubi , Jérôme Darmont

The past decade has witnessed order of magnitude increases in computing power, data storage capacity and network speed, giving birth to applications which may handle large data volumes of increased complexity, distributed over the Internet.…

Databases · Computer Science 2007-05-23 F Estrella , C del Frate , T Hauer , R McClatchey , M Odeh , D Rogulin , S R Amendolia , D Schottlander , T Solomonides , R Warren