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The shape deformation of a three-dimensional axisymmetric vesicle with encapsulated filaments or impurities is analyzed by integrating a dissipation dynamics. This method can incorporate systematically the constraint of a fixed surface area…

Soft Condensed Matter · Physics 2009-11-07 Akiyoshi shibuya , Yukio Saito , Hiroyuki Hyuga

A transient analysis for vesicle deformation under DC electric fields is developed. The theory extends from a droplet model, with the additional consideration of a lipid membrane separating two fluids of arbitrary properties. For the…

Biological Physics · Physics 2015-06-12 Jia Zhang , Jeffery D. Zahn , Wenchang Tan , Hao Lin

Vesicles are micrometric soft particles whose the membrane is a two-dimensional incompressible fluid governed by bending resistance leading to a zoology of shapes. The dynamics of deflated vesicles in shear flow with a bottom wall, a first…

Soft Condensed Matter · Physics 2019-09-10 Maximilien Degonville , Gwenn Boedec , Marc Leonetti

Vesicle dynamics in unbounded Poiseuille flow is analyzed using a small-deformation theory. Our analytical results quantitatively describe vesicle migration and provide new physical insights. At low ratio between the inner and outer…

Biological Physics · Physics 2015-05-13 Gerrit Danker , Petia Vlahovska , Chaouqi Misbah

In this paper, the dynamics of spontaneous shape fluctuations of a single, giant quasi-spherical vesicle formed of a single lipid species is revisited theoretically. A coherent physical theory for the dynamics is developed based on a number…

Soft Condensed Matter · Physics 2009-11-07 Ling Miao , Michael A. Lomholt , Jesper Kleis

The steady motion and deformation of a lipid-bilayer vesicle translating through a circular tube in low Reynolds number pressure-driven flow are investigated numerically using an axisymmetric boundary element method. This fluid-structure…

Fluid Dynamics · Physics 2020-05-05 Paul G. Chen , J. M. Lyu , M. Jaeger , M. Leonetti

Biological cells are able to generate intricate structures and respond to external stimuli, sculpting their membrane from within. Simplified biomimetic systems can aid in understanding the principles which govern these shape changes and…

Non-uniform fields are commonly used to study vesicle dielectrophoresis and can be used to hitherto relatively unexplored areas of vesicle deformation and electroporation. A common but perplexing problem in vesicle dynamics is the cross…

Soft Condensed Matter · Physics 2018-12-26 Kumari Priti Sinha , Rochish M Thaokar

Biological membranes constantly change their shape in response to external stimuli, and understanding the remodeling and stability of vesicles in heterogeneous environments is therefore of fundamental importance for a range of cellular…

Soft Condensed Matter · Physics 2022-12-20 Håkan Wennerström , Emma Sparr , Joakim Stenhammar

We study elasticity-driven morphological transitions of soft spherical core shell structures in which the core can be treated as an isotropic elastic continuum and the surface or shell as a tensionless liquid layer, whose elastic response…

Soft Condensed Matter · Physics 2013-11-13 Craig Fogle , Amy C. Rowat , Alex J. Levine , Joseph Rudnick

We analytically derive an equation describing vesicle evolution in a fluid where some stationary flow is excited regarding that the vesicle shape is close to a sphere. A character of the evolution is governed by two dimensionless…

Soft Condensed Matter · Physics 2009-11-13 V. V. Lebedev , K. S. Turitsyn , S. S. Vergeles

(200 words) Oxidation of unsaturated lipids is a fundamental process involved in cell bioenergetics as well as in cell death. Using giant unilamellar vesicles and a chlorin photosensitizer, we asymmetrically oxidized the outer or inner…

Biological Physics · Physics 2019-02-27 Julien Heuvingh , Stéphanie Bonneau

We develop a self-consistent free-energy framework in which membrane shape and osmotic pressure are determined simultaneously in a finite reservoir by minimizing bending elasticity and solute entropy. Solute conservation makes osmotic…

Lipid vesicles play a key role in fundamental biological processes. Despite recent progress, we lack a complete understanding of the non-equilibrium dynamics of vesicles due to challenges associated with long-time observation of shape…

Biological Physics · Physics 2019-10-18 Dinesh Kumar , Channing M. Richter , Charles M. Schroeder

The shape transformations of fluid membranes induced by curved protein rods are studied using meshless membrane simulations. The rod assembly at low rod density induces a flat membrane tube and oblate vesicle. It is found that the…

Soft Condensed Matter · Physics 2015-09-30 Hiroshi Noguchi

Motivated by recent studies of two-phase lipid vesicles possessing 2D solid domains integrated within a fluid bilayer phase, we study the shape equilibria of closed vesicles possessing a single planar, circular inclusion. While 2D solid…

Soft Condensed Matter · Physics 2024-04-16 Geunwoong Jeon , Justin Fagnoni , Hao Wan , Maria M. Santore , Gregory M. Grason

Recent experiments on vesicles formed from block copolymers with liquid-crystalline side-chains reveal a rich variety of vesicle morphologies. The additional internal order ("structure") developed by these self-assembled block copolymer…

Soft Condensed Matter · Physics 2012-05-21 Xiangjun Xing , Homin Shin , Mark J. Bowick , Zhenwei Yao , Lin Jia , Min-Hui Li

In biology, cells undergo deformations under the action of flow caused by the fluid surrounding them. These flows lead to shape changes and instabilities that have been explored in detail for single component vesicles. However, cell…

Fluid Dynamics · Physics 2025-10-15 Anirudh Venkatesh , Vivek Narsimhan

Many vesicles have a spherical resting shape and exposure to fluid flows induces an exchange between sub-optical area and visible (systematic) deformation, while the total area is conserved. The dynamics which controls the exchange between…

Soft Condensed Matter · Physics 2020-06-19 Afsoun Rahnama Falavarjani , David Salac

We examine the deformation of homogeneous spherical fluid vesicles along their equator by a circular rigid ring. We consider deformations preserving the axial and equatorial mirror symmetries of the vesicles. The configurations of the…

Soft Condensed Matter · Physics 2025-03-27 Pablo Vázquez-Montejo , Bojan Božič , Jemal Guven