Related papers: RSC remodeling of oligo-nucleosomes: an atomic for…
Classifying the various shapes and attributes of a glioma cell nucleus is crucial for diagnosis and understanding the disease. We investigate automated classification of glioma nuclear shapes and visual attributes using Convolutional Neural…
High-grade serous ovarian carcinoma (HGSOC) is characterised by significant spatial and temporal heterogeneity, typically manifesting at an advanced metastatic stage. A major challenge in treating advanced HGSOC is effectively monitoring…
Target mass correction (TMC) is being used to improve the theoretical results for the nucleon structure functions. This improvement makes the fitting more reliable with the available experimental data in lepton scattering off the nucleon .…
The presence of motion artifacts in magnetic resonance imaging (MRI) scans poses a significant challenge, where even minor patient movements can lead to artifacts that may compromise the scan's utility.This paper introduces MAsked MOtion…
Using force as a probe to map the folding landscapes of RNA molecules has become a reality thanks to major advances in single molecule pulling experiments. Although the unfolding pathways under tension are complicated to predict studies in…
Histone variants regulate replication, transcription, DNA damage repair, and chromosome segregation. Though widely accepted as a paradigm, it has not been rigorously demonstrated that histone variants encode unique mechanical properties.…
Chromatin moves dynamically inside the cell nucleus, and its motion is often correlated with gene functions such as DNA recombination and transcription. A recent study has shown that during early embryogenesis of the nematode,…
Nucleosome organization in eukaryotic genomes has a deep impact on gene function. Although progress has been recently made in the identification of various concurring factors influencing nucleosome positioning, it is still unclear whether…
The encoder-decoder networks are commonly used in medical image segmentation due to their remarkable performance in hierarchical feature fusion. However, the expanding path for feature decoding and spatial recovery does not consider the…
The Cancer Genome Atlas project was initiated by the National Cancer Institute in order to characterize the genomes of hundreds of tumors of various cancer types. While much effort has been put into detecting somatic genomic variation in…
Recent advances in nonlocal metasurfaces have enabled unprecedented success in shaping the wavefront of light with spectral selectivity, offering new solutions for many emerging nanophotonics applications. The ability to tune both the…
Nanoscale chromatin domains, variously termed nucleosome clutches, nanodomains, or packing domains, have emerged as fundamental architectural units of the mammalian genome during interphase and mitosis. Unlike cohesin-dependent loops or…
Collective inertial mass coefficients with respect to translational, relative, and rotational motions are microscopically calculated, along the collective reaction path self-consistently determined, based on the adiabatic self-consistent…
The conventional cranking model for uniaxial and triaxial rotation (CCRM3) is frequently used to study rotational features in deformed nuclei. However, CCRM3 is semi-classical and phenomenological because it uses a constant angular…
This paper reports on a novel template-free monocular non-rigid surface reconstruction approach. Existing techniques using motion and deformation cues rely on multiple prior assumptions, are often computationally expensive and do not…
De novo prediction of protein folding is an open scientific challenge. Many folding models and force fields have been developed, yet all face difficulties converging to native conformations. Hydrophobicity scales (HSs) play a crucial role…
Stacking faults (SF) are important structural defects that play an essential role in the deformation of engineering alloys. However, direct observation of stacking faults at the atomic scale can be challenging. Here, we use the analytical…
Rashba spin-orbit coupling (RSOC) induces strong momentum-dependent spin splitting and plays a crucial role in fields like spintronics and topological photonics. We here theoretically investigate the collective excitations in monolayer…
The three dimensional structure of DNA in the nucleus (chromatin) plays an important role in many cellular processes. Recent experimental advances have led to high-throughput methods of capturing information about chromatin conformation on…
Oral Squamous Cell Carcinoma (OSCC) is a prevalent and aggressive malignancy where deep learning-based computer-aided diagnosis and prognosis can enhance clinical assessments.However, existing publicly available OSCC datasets often suffer…