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Stimulus from the environment that guides behavior and informs decisions is encoded in the firing rates of neural populations. Each neuron in the populations, however, does not spike independently: spike events are correlated from cell to…

Neurons and Cognition · Quantitative Biology 2012-07-24 Nicholas Cain , Eric Shea-Brown

We present a first-order non-homogeneous Markov model for the interspike-interval density of a continuously stimulated spiking neuron. The model allows the conditional interspike-interval density and the stationary interspike-interval…

Neurons and Cognition · Quantitative Biology 2012-08-15 J. Tapson , C. Jin , A. van Schaik , R. Etienne-Cummings

High-order interdependencies are central features of complex systems, yet a mechanistic explanation for their emergence remains elusive. Currently, it is unknown under what conditions high-order interdependencies, quantified by the…

Physics and Society · Physics 2026-03-03 Enrico Caprioglio , Pedro A. M. Mediano , Luc Berthouze

Complex networks have become the main paradigm for modelling the dynamics of interacting systems. However, networks are intrinsically limited to describing pairwise interactions, whereas real-world systems are often characterized by…

Synchronization is a ubiquitous phenomenon in complex systems. The Kuramoto model serves as a paradigmatic framework for understanding how coupled oscillators achieve collective rhythm. Conventional approaches focus on pairwise…

Adaptation and Self-Organizing Systems · Physics 2026-03-16 Zheng Wang , Jinjie Zhu , Xianbin Liu

How spiking activity reverberates through neuronal networks, how evoked and spontaneous activity interact and blend, and how the combined activities represent external stimulation are pivotal questions in neuroscience. We simulated minimal…

Neurons and Cognition · Quantitative Biology 2018-03-01 Christoph Bauermeister , Hanna Keren , Jochen Braun

Understanding and controlling the mechanisms behind synchronization phenomena is of paramount importance in nonlinear science. In particular, the emergence of chimera states, patterns in which order and disorder coexist simultaneously,…

Pattern Formation and Solitons · Physics 2025-10-22 Riccardo Muolo , Lucia Valentina Gambuzza , Hiroya Nakao , Mattia Frasca

We study pairwise Ising models for describing the statistics of multi-neuron spike trains, using data from a simulated cortical network. We explore efficient ways of finding the optimal couplings in these models and examine their…

Quantitative Methods · Quantitative Biology 2009-05-21 Yasser Roudi , Joanna Tyrcha , John Hertz

Motifs are patterns of subgraphs of complex networks. We studied the impact of such patterns of connectivity on the level of correlated, or synchronized, spiking activity among pairs of cells in a recurrent network model of integrate and…

Neurons and Cognition · Quantitative Biology 2015-06-05 Yu Hu , James Trousdale , Kresimir Josic , Eric Shea-Brown

Although stochastic resonance phenomena are ubiquitous across various complex systems, the influence mechanisms of higher-order interactions remain elusive. Here, we address this gap by investigating stochastic resonance in coupled phase…

Adaptation and Self-Organizing Systems · Physics 2026-03-16 Zheng Wang , Jinjie Zhu , Xianbin Liu

Synchronization is a fundamental phenomenon in complex systems, observed across a wide range of natural and engineered contexts. The Kuramoto model provides a foundational framework for understanding synchronization among coupled…

Adaptation and Self-Organizing Systems · Physics 2026-02-03 Riccardo Muolo , Hiroya Nakao , Marco Coraggio

Hypergraphs, encoding structured interactions among any number of system units, have recently proven a successful tool to describe many real-world biological and social networks. Here we propose a framework based on statistical inference to…

Social and Information Networks · Computer Science 2022-12-01 Martina Contisciani , Federico Battiston , Caterina De Bacco

Cortical neurons whose activity is recorded in behavioral experiments has been classified into several types such as stimulus-related neurons, delay-period neurons, and reward-related neurons. Moreover, the population activity of neurons…

Neurons and Cognition · Quantitative Biology 2018-11-27 Takuma Tanaka

Several recent experiments in biology study systems composed of several interacting elements, for example neuron networks. Normally, measurements describe only the collective behavior of the system, even if in most cases we would like to…

Disordered Systems and Neural Networks · Physics 2010-10-12 Vitor Sessak

Spike timing dependent plasticity (STDP) is believed to play an important role in shaping the structure of neural circuits. Here we show that STDP generates effective interactions between synapses of different neurons, which were neglected…

Neurons and Cognition · Quantitative Biology 2016-08-25 Neta Ravid Tannenbaum , Yoram Burak

An essential step toward understanding neural circuits is linking their structure and their dynamics. In general, this relationship can be almost arbitrarily complex. Recent theoretical work has, however, begun to identify some broad…

Neurons and Cognition · Quantitative Biology 2017-03-10 Gabriel Koch Ocker , Yu Hu , Michael A. Buice , Brent Doiron , Krešimir Josić , Robert Rosenbaum , Eric Shea-Brown

Pairwise interactions between perturbations to a system can provide evidence for the causal dependencies of the underlying underlying mechanisms of a system. When observations are low dimensional, hand crafted measurements, detecting…

Machine Learning · Computer Science 2024-09-13 Zuheng , Xu , Moksh Jain , Ali Denton , Shawn Whitfield , Aniket Didolkar , Berton Earnshaw , Jason Hartford

The functional significance of correlations between action potentials of neurons is still a matter of vivid debates. In particular it is presently unclear how much synchrony is caused by afferent synchronized events and how much is…

Neurons and Cognition · Quantitative Biology 2013-04-09 Matthias Schultze-Kraft , Markus Diesmann , Sonja Grün , Moritz Helias

We address the questions of identifying pairs of interacting neurons from the observation of their spiking activity. The neuronal network is modeled by a system of interacting point processes with memory of variable length. The influence of…

Statistics Theory · Mathematics 2021-06-22 Emilio De Santis , Antonio Galves , Giovanna Nappo , Mauro Piccioni

Molecular interactions have widely been modelled as networks. The local wiring patterns around molecules in molecular networks are linked with their biological functions. However, networks model only pairwise interactions between molecules…

Molecular Networks · Quantitative Biology 2018-09-21 Thomas Gaudelet , Noel Malod-Dognin , Natasa Przulj