Related papers: Localised IR spectroscopy of hemoglobin
Imaging single proteins has been a long-standing ambition for advancing various fields in natural science, as for instance structural biology, biophysics and molecular nanotechnology. In particular, revealing the distinct conformations of…
Previous studies demonstrated that infrared absorption spectra of blood sera may help disease detection. For clinical translation of this approach, it is important to determine the molecular origin of disease-related spectral perturbations.…
This paper examines the potential contribution of infrared (IR) imaging in breast diseases detection. It compares obtained results using some algorithms for detection of malignant breast conditions such as Support Vector Machine (SVM)…
The in situ combination of Scanning Probe Microscopies (SPM) with X-ray microbeams adds a variety of new possibilities to the panoply of synchrotron radiation techniques. In this paper we describe an optics-free AFM/STM that can be directly…
Optical spectroscopy constitutes the historical path to accumulate basic knowledge on the atom and its structure. Former work based on fluorescence and resonance ionization spectroscopy enabled identifying optical spectral lines up to…
The size of a probe bead reported by holographic particle characterization depends on the proportion of the surface area covered by bound target molecules and so can be used as an assay for molecular binding. We validate this technique by…
Droplet microfluidics has emerged as a powerful platform allowing a large number of individual reactions to be carried out in spatially distinct microcompartments. Due to their small size, however, the spectroscopic characterisation of…
Infrared (IR) imaging is one of the significant tools for the quality control measurements of fabricated samples. Standard IR imaging techniques use direct measurements, where light sources and detectors operate at IR range. Due to the…
Numerous molecules exhibit unique absorption bands in the fingerprint infrared (IR) region, allowing chemical identification and detection. This makes IR spectroscopy an essential tool in biomedical diagnostics, sensing, and material…
A new modeling way of describing the continuous absorption of electromagnetic (EM) radiation in dense partially ionized hydrogen plasma is tested in this work. It is shown that the obtained results give a possibility of calculating spectral…
Tissue oxygenation and perfusion can be an indicator for organ viability during minimally invasive surgery, for example allowing real-time assessment of tissue perfusion and oxygen saturation. Multispectral imaging is an optical modality…
We present a novel approach to calculate molecular IR spectra based on semiclassical molecular dynamics. The main advance from a previous semiclassical method [M. Micciarelli, R. Conte, J. Suarez, M. Ceotto J. Chem. Phys. 149, 064115…
We present a system for molecular spectroscopy using a broadband mid-infrared laser with near infrared detection. Difference frequency generation of a Yb:fiber femtosecond laser produced a mid-infrared (MIR) source tunable from 2100-3700…
Molecular fingerprinting through absorption spectroscopy is a powerful analytical method. Wide spectral ranges are explored with Doppler-limited resolution. Fast data acquisition, accurate measurements of frequency, intensity, and line…
Adaptive optics enables the deployment of interferometer-based spectroscopy without the need for moving parts necessary for scanning the interferometer arms. Here, we employ a Michelson Interferometer in conjunction with a Spatial Light…
We investigate quantum spectroscopy with undetected photons for protein detection in the mid-infrared spectral region. Classical Fourier-transform infrared spectroscopy of protein samples (bovine serum albumin and N-terminal pro-brain…
High-resolution gas phase spectroscopy techniques in the microwave, millimeter-wave and terahertz spectral ranges can be used to study complex organic molecules desorbed from interstellar ice analogues surface with a high sensitivity.…
The sensitivity of imaging spectroscopy to haemoglobin derivatives makes it a promising tool for detecting blood. However, due to complexity and high dimensionality of hyperspectral images, the development of hyperspectral blood detection…
Traditional absorption spectroscopy has fundamental difficulty in resolving small absorbance from strong background due to the instability of laser sources. Existing background-free methods in broadband vibrational spectroscopy help to…
The paper describes the peculiarities of acquirement and interpretation of images of current distribution through the sample surface when operating in I-AFM mode. It shows that I-AFM and SCM modes can be successfully used only for small…