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Theory predicts rapid genetic drift during invasions, yet many expanding populations maintain high genetic diversity. We find that genetic drift is dramatically suppressed when dispersal rates increase with the population density because…

Populations and Evolution · Quantitative Biology 2019-03-29 Gabriel Birzu , Sakib Matin , Oskar Hallatschek , Kirill S. Korolev

The accumulation of beneficial mutations on many competing genetic backgrounds in rapidly adapting populations has a striking impact on evolutionary dynamics. This effect, known as clonal interference, causes erratic fluctuations in the…

Populations and Evolution · Quantitative Biology 2013-05-31 Katya Kosheleva , Michael Desai

There exists a wide variety of works on the dynamics of large populations ranging from simple heuristic modeling to those based on advanced computer supported methods. Their interconnections, however, remain mostly vague, which…

Dynamical Systems · Mathematics 2023-04-27 Yuri Kozitsky , Krzysztof Pilorz

This paper introduces a variational formulation of natural selection, paying special attention to the nature of "things" and the way that different "kinds" of "things" are individuated from - and influence - each other. We use the Bayesian…

Populations and Evolution · Quantitative Biology 2023-07-05 Karl Friston , Daniel Ari Friedman , Axel Constant , V. Bleu Knight , Thomas Parr , John O. Campbell

We consider the hypothesis that Evolution promotes population-wide genome patterns that, under randomization, ensures the External Validity of adaptations across population members. An adaptation is Externally Valid (EV) if its effect holds…

Populations and Evolution · Quantitative Biology 2021-08-17 Andre F. Ribeiro

We propose a mathematical framework for natural selection in finite populations. Traditionally, many of the selection-based processes used to describe cultural and genetic evolution (such as imitation and birth-death models) have been…

Populations and Evolution · Quantitative Biology 2015-11-18 Alex McAvoy

Recurrent mutations are a common phenomenon in population genetics. They may be at the origin of the fixation of a new genotype, if they give a phenotypic advantage to the carriers of the new mutation. In this paper, we are interested in…

Probability · Mathematics 2016-11-28 Charline Smadi

We introduce a new parameter to discuss the behavior of a genetic algorithm. This parameter is the mean number of exact copies of the best fit chromosomes from one generation to the next. We argue that the genetic algorithm should operate…

Neural and Evolutionary Computing · Computer Science 2015-12-04 Raphaël Cerf

The selection pressures that have shaped the evolution of complex traits in humans remain largely unknown, and in some contexts highly contentious, perhaps above all where they concern mean trait differences among groups. To date, the…

Populations and Evolution · Quantitative Biology 2020-10-08 Arbel Harpak , Molly Przeworski

When studying the dynamics of trait distribution of populations in a heterogeneous environment, classical models from quantitative genetics choose to look at its system of moments, specifically the first two ones. Additionally, in order to…

Populations and Evolution · Quantitative Biology 2020-12-21 Léonard Dekens

Evolutionary games on graphs describe how strategic interactions and population structure determine evolutionary success, quantified by the probability that a single mutant takes over a population. Graph structures, compared to the…

Populations and Evolution · Quantitative Biology 2017-05-08 Philipp M. Altrock , Arne Traulsen , Martin A. Nowak

The ability of random environmental variation to stabilize competitor coexistence was pointed out long ago and, in recent years, has received considerable attention. Analyses have focused on variations in the log-abundances of species, with…

Populations and Evolution · Quantitative Biology 2020-04-14 Antony Dean , Nadav M. Shnerb

A fundamental theory is presented for the mechanical response of polymer networks undergoing large deformation which seamlessly integrates statistical mechanical principles with macroscopic thermodynamic constitutive theory. Our formulation…

Soft Condensed Matter · Physics 2020-07-06 Michael R. Buche , Meredith N. Silberstein

This work presents a population genetic model of evolution, which includes haploid selection, mutation, recombination, and drift. The mutation-selection equilibrium can be expressed exactly in closed form for arbitrary fitness functions…

Populations and Evolution · Quantitative Biology 2023-02-28 Jenny M. Poulton , Lee Altenberg , Chris Watkins

Biological evolution depends on the passing down to subsequent generations of genetic information encoding beneficial traits, and on the removal of unfit individuals by a selection mechanism. However, selection acts on phenotypes, and is…

Populations and Evolution · Quantitative Biology 2026-05-01 Bastien Mallein , Francesco Paparella , Emmanuel Schertzer , Zsófia Talyigás

Numerous traits under migration-selection balance are shown to exhibit complex patterns of genetic architecture with large variance in effect sizes. However, the conditions under which such genetic architectures are stable have yet to be…

Populations and Evolution · Quantitative Biology 2022-11-01 Léonard Dekens , Sarah P. Otto , Vincent Calvez

We model and study the genetic evolution and conservation of a population of diploid hermaphroditic organisms, evolving continuously in time and subject to resource competition. In the absence of mutations, the population follows a 3-type…

Probability · Mathematics 2012-07-23 Camille Coron

To understand the effect of assortative mating on the genetic evolution of a population, we consider a finite population in which each individual has a type, determined by a sequence of n diallelic loci. We assume that the population…

Probability · Mathematics 2023-11-30 Alison M. Etheridge , Sophie Lemaire

Horizontal transfer (HT) of heritable information or `traits' (carried by genetic elements, endosymbionts, or culture) is widespread among living organisms. Yet current ecological and evolutionary theory addressing HT is limited. We present…

Populations and Evolution · Quantitative Biology 2015-12-01 Sylvain Billiard , Pierre Collet , Régis Ferrière , Sylvie Méléard , Viet Chi Tran

We consider the Moran model of population genetics with two types, mutation, and selection, and investigate the line of descent of a randomly-sampled individual from a contemporary population. We trace this ancestral line back into the…

Probability · Mathematics 2024-05-22 Ellen Baake , Enrico Di Gaspero , Fernando Cordero
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