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There is now a certain consensus that Transcription Factors (TFs) reach their target sites, where they regulate gene transcription, via a mechanism dubbed facilitated diffusion (FD). In FD, the TF cycles between events of 3D-diffusion in…

Biomolecules · Quantitative Biology 2015-06-18 Carlo Guardiani , Massimo Cencini , Fabio Cecconi

Tremendous experimental and theoretical attempts to find carbon based two-dimensional semiconductors have yielded a wide variety of graphene polymorphs, such as carbon-nitride, carbonboride, graphyne and graphdiyne 2D materials with highly…

Materials Science · Physics 2020-03-09 S. Milad Hatam-Lee , Ali Rajabpour , Sebastian Volz

Accurate knowledge of the thermodynamic properties of nucleic acids is crucial to predicting their structure and stability. To date most measurements of base-pair free energies in DNA are obtained in thermal denaturation experiments, which…

Biological Physics · Physics 2010-10-07 J. M. Huguet , C. V. Bizarro , N. Forns , S. B. Smith , C. Bustamante , F. Ritort

The thermal conductivities of beta-Ga2O3 single crystals along four different crystal directions were measured in the temperature range of 80-495K using the time domain thermoreflectance (TDTR) method. A large anisotropy was found. At room…

Modelling micro- and meso-scopic scale thermodynamic and transport properties of soft condensed matter hinges upon its representation. This is especially relevant for polar solvents such as water, since these require effective…

Soft Condensed Matter · Physics 2026-04-17 Michael A. Seaton , Benjamin T. Speake , Ilian T. Todorov

The thermophysical properties of supported and free-standing nanomaterials would be different due to the substrate effect. To determine the thermophysical properties of supported 2D nanomaterials, this paper developed a two-step…

Instrumentation and Detectors · Physics 2021-09-02 Aoran Fan , Haidong Wang , Weigang Ma , Xing Zhang

We study the elastic behaviour of a supercoiled DNA molecule. The simplest model is that of a rod like chain, involving two elastic constants, the bending and the twist rigidities. We show that this model is singular and needs a small…

Condensed Matter · Physics 2009-10-31 Claude Bouchiat , Marc Mezard

Coarse-grained models have emerged as valuable tools to simulate long DNA molecules while maintaining computational efficiency. These models aim at preserving interactions among coarse-grained variables in a manner that mirrors the…

Soft Condensed Matter · Physics 2024-05-01 Wout Laeremans , Midas Segers , Aderik Voorspoels , Enrico Carlon , Jef Hooyberghs

We propose using graphene electrodes with hydrogenated edges for solid-state nanopore-based DNA sequencing, and perform molecular dynamics simulations in conjunction with electronic transport calculations to explore the potential merits of…

Biological Physics · Physics 2011-08-03 Yuhui He , Ralph H. Scheicher , Anton Grigoriev , Rajeev Ahuja , Shibing Long , ZongLiang Huo , Ming Liu

DNA self-assembly is a well-understood nanotechnology to obtain extremely ordered structures from the nanometer to up to the hundred of microns scale. By contrast, DNA hydrogels rely on the disordered assembly of DNA building blocks to…

We studied the electrical conductivity of DNA samples as function of the number of DNA molecules. We showed that the insulating gap (no current at low voltage) increases from ~1-2 V for bundles and large ropes to ~4-7 V for few DNA…

Soft Condensed Matter · Physics 2007-05-23 Thomas Heim , Dominique Deresemes , Dominique Vuillaume

Inspired by some recent molecular dynamics (MD) simulations and experiments on suspended graphene nanoribbons, we study a simplified model where the atoms are disposed in a rectangular lattice coupled by nearest neighbor interactions which…

Mesoscale and Nanoscale Physics · Physics 2015-10-20 R. Barreto , M. F. Carusela , A. Mancardo Viotti , A. G. Monastra

The most popular and universally predictive protein simulation models employ all-atom molecular dynamics (MD), but they come at extreme computational cost. The development of a universal, computationally efficient coarse-grained (CG) model…

We demonstrate simultaneous measurements of DNA translocation into glass nanopores using ionic current detection and fluorescent imaging. We verify the correspondence between the passage of a single DNA molecule through the nanopore and the…

Anomalous heat transport in one-dimensional nanostructures, such as nanotubes and nanowires, is a widely debated problem in condensed matter and statistical physics, with contradicting pieces of evidence from experiments and simulations.…

Mesoscale and Nanoscale Physics · Physics 2021-07-14 Giuseppe Barbalinardo , Zekun Chen , Haikuan Dong , Zheyong Fan , Davide Donadio

The extremely high thermal conductivity of graphene has received great attention both in experiments and calculations. Obviously, new feature in thermal properties is of primary importance for application of graphene-based materials in…

Materials Science · Physics 2018-08-10 Haifei Zhan , Gang Zhang , Chunhui Yang , Yuantong Gu

Thermal properties of covalent organic frameworks (COFs) are of fundamental interest owing to exceptional heat conduction properties. Recent studies have suggested that their thermal conductivities can be enhanced by multiple factors such…

Materials Science · Physics 2025-07-31 Sungjae Kim , Taeyong Kim

The imaginary time path integral formalism is applied to a nonlinear Hamiltonian for a short fragment of heterogeneous DNA with a stabilizing solvent interaction term. Torsional effects are modeled by a twist angle between neighboring base…

Biomolecules · Quantitative Biology 2011-09-19 Marco Zoli

Recent advances in operating and manipulating DNA have provided unique experimental possibilities in many fields of DNA research, especially in gene therapy. Researchers have deployed many techniques, experimental and theoretical, to study…

Soft Condensed Matter · Physics 2023-01-04 Arghya Maity , Neha Mathur , Petra Imhof , Navin Singh

Effective thermal conductivity is an important property of composites for different thermal management applications. Although physics-based methods, such as effective medium theory and solving partial differential equation, dominate the…

Computational Physics · Physics 2019-04-15 Qingyuan Rong , Han Wei , Hua Bao
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