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Stochastic kinetic models are often used to describe complex biological processes. Typically these models are analytically intractable and have unknown parameters which need to be estimated from observed data. Ideally we would have…

Computation · Statistics 2018-03-13 Richard J. Boys , Holly F. Ainsworth , Colin S. Gillespie

We revisit empirical Bayes discrimination detection, focusing on uncertainty arising from both partial identification and sampling variability. While prior work has mostly focused on partial identification, we find that some empirical…

Econometrics · Economics 2025-08-19 Jiaying Gu , Nikolaos Ignatiadis , Azeem M. Shaikh

Especially when facing reliability data with limited information (e.g., a small number of failures), there are strong motivations for using Bayesian inference methods. These include the option to use information from physics-of-failure or…

Methodology · Statistics 2022-10-27 Qinglong Tian , Colin Lewis-Beck , Jarad Niemi , William Meeker

Interim analyses are vital in clinical trials for early decision-making. While frequentist implications are well-established, the consequences of repeated Bayesian interim monitoring for efficacy, specifically regarding multiplicity, remain…

Methodology · Statistics 2025-12-30 Suyu Liu , Beibei Guo , Laura Thompson , Lei Nie , Ying Yuan

The problem of nonparametric estimation of the conditional density of a response, given a vector of explanatory variables, is classical and of prominent importance in many prediction problems since the conditional density provides a more…

Methodology · Statistics 2015-04-21 Catia Scricciolo

A new method is proposed for the correction of confidence intervals when the original interval does not have the correct nominal coverage probabilities in the frequentist sense. The proposed method is general and does not require any…

Computation · Statistics 2013-08-30 P. Menendez , Y. Fan , P. H. Garthwaite , S. A. Sisson

It is not always clear how to adjust for control data in causal inference, balancing the goals of reducing bias and variance. We show how, in a setting with repeated experiments, Bayesian hierarchical modeling yields an adaptive procedure…

Methodology · Statistics 2025-01-23 Andrew Gelman , Matthijs Vákár

Consider the Gaussian sequence model under the additional assumption that a fixed fraction of the means is known. We study the problem of variance estimation from a frequentist Bayesian perspective. The maximum likelihood estimator (MLE)…

Statistics Theory · Mathematics 2019-12-19 Gianluca Finocchio , Johannes Schmidt-Hieber

Large-sample Bayesian analogs exist for many frequentist methods, but are less well-known for the widely-used 'sandwich' or 'robust' variance estimates. We review existing approaches to Bayesian analogs of sandwich variance estimates and…

Methodology · Statistics 2023-11-06 Kendrick Qijun Li , Kenneth Martin Rice

Bayesian analysis is increasingly popular for use in social science and other application areas where the data are observations from an informative sample. An informative sampling design leads to inclusion probabilities that are correlated…

Statistics Theory · Mathematics 2016-06-07 Terrance D. Savitsky , Daniell Toth

Sensitivity Analysis is a framework to assess how conclusions drawn from missing outcome data may be vulnerable to departures from untestable underlying assumptions. We extend the E-value, a popular metric for quantifying robustness of…

Methodology · Statistics 2021-08-31 Wu Xue , Abbas Zaidi

The information flow-based quantitative causality analysis has been widely applied in different disciplines because of its origin from first principles, its concise form, and its computational efficiency. So far the algorithm for its…

Adaptation and Self-Organizing Systems · Physics 2023-03-08 X. San Liang

A density estimation method in a Bayesian nonparametric framework is presented when recorded data are not coming directly from the distribution of interest, but from a length biased version. From a Bayesian perspective, efforts to…

Statistics Theory · Mathematics 2015-10-23 Spyridon J. Hatjispyros , Theodoros Nicoleris , Stephen G. Walker

When combining apparently inconsistent experimental results, one often implements errors on errors. The Particle Data Group's phenomenological prescription offers a practical solution but lacks a firm theoretical foundation. To address…

High Energy Physics - Phenomenology · Physics 2025-08-22 Satoshi Mishima , Kin-ya Oda

For a Bayesian, real-time forecasting with the posterior predictive distribution can be challenging for a variety of time series models. First, estimating the parameters of a time series model can be difficult with sample-based approaches…

Applications · Statistics 2022-08-08 Taylor R. Brown

Motivated by recently emerging problems in machine learning and statistics, we propose data models which relax the familiar i.i.d. assumption. In essence, we seek to understand what it means for data to come from a set of probability…

Statistics Theory · Mathematics 2025-01-08 Christian Fröhlich , Robert C. Williamson

In this note we present studies of coverage and power for confidence intervals for a Poisson process with known background calculated using the Likelihood ratio (aka Feldman & Cousins) ordering with Bayesian treatment of uncertainties in…

Data Analysis, Statistics and Probability · Physics 2017-08-23 Jan Conrad , Fredrik Tegenfeldt

In statistical practice, whether a Bayesian or frequentist approach is used in inference depends not only on the availability of prior information but also on the attitude taken toward partial prior information, with frequentists tending to…

Statistics Theory · Mathematics 2012-05-02 David R. Bickel

Non-representative surveys are commonly used and widely available but suffer from selection bias that generally cannot be entirely eliminated using weighting techniques. Instead, we propose a Bayesian method to synthesize longitudinal…

Methodology · Statistics 2024-07-08 Nathaniel Dyrkton , Paul Gustafson , Harlan Campbell

This paper addresses the problem of detecting and characterizing local variability in time series and other forms of sequential data. The goal is to identify and characterize statistically significant variations, at the same time…

Instrumentation and Methods for Astrophysics · Physics 2015-06-05 Jeffrey D. Scargle , Jay P. Norris , Brad Jackson , James Chiang