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We study the problem of efficiently clustering protein sequences in a limited information setting. We assume that we do not know the distances between the sequences in advance, and must query them during the execution of the algorithm. Our…

Data Structures and Algorithms · Computer Science 2015-03-17 Konstantin Voevodski , Maria-Florina Balcan , Heiko Roglin , Shang-Hua Teng , Yu Xia

We apply the concept of subset seeds proposed in [1] to similarity search in protein sequences. The main question studied is the design of efficient seed alphabets to construct seeds with optimal sensitivity/selectivity trade-offs. We…

Quantitative Methods · Quantitative Biology 2011-01-18 Mikhail A. Roytberg , Anna Gambin , Laurent Noé , Slawomir Lasota , Eugenia Furletova , Ewa Szczurek , Gregory Kucherov

Exact structured inference with neural network scoring functions is computationally challenging but several methods have been proposed for approximating inference. One approach is to perform gradient descent with respect to the output…

Computation and Language · Computer Science 2019-07-09 Lifu Tu , Kevin Gimpel

Feature subset selection, as a special case of the general subset selection problem, has been the topic of a considerable number of studies due to the growing importance of data-mining applications. In the feature subset selection problem…

Machine Learning · Computer Science 2014-11-13 Tofigh Naghibi , Sarah Hoffmann , Beat Pfister

We consider strategies to organize easily updatable associative arrays in external memory. These arrays are used for full-text search. We study indexes with different keys: single word form, two word forms, and sequences of word forms. The…

Information Retrieval · Computer Science 2020-07-21 Alexander B. Veretennikov

Identification and alignment of three-dimensional folding of proteins may yield useful information about relationships too remote to be detected by conventional methods, such as sequence comparison, and may potentially lead to prediction of…

Quantitative Methods · Quantitative Biology 2017-01-10 Barış Ekim

An overview of current multiple alignment systems to date are described.The useful algorithms, the procedures adopted and their limitations are presented.We also present the quality of the alignments obtained and in which cases(kind of…

Data Structures and Algorithms · Computer Science 2009-01-20 Fahad Saeed , Ashfaq Khokhar

Dimensionality reduction is crucial both for visualization and preprocessing high dimensional data for machine learning. We introduce a novel method based on a hierarchy built on 1-nearest neighbor graphs in the original space which is used…

Computer Vision and Pattern Recognition · Computer Science 2022-05-31 M. Saquib Sarfraz , Marios Koulakis , Constantin Seibold , Rainer Stiefelhagen

Data series classification is an important and challenging problem in data science. Explaining the classification decisions by finding the discriminant parts of the input that led the algorithm to some decisions is a real need in many…

Machine Learning · Computer Science 2022-07-26 Paul Boniol , Mohammed Meftah , Emmanuel Remy , Themis Palpanas

Given a set of sequences, the distance between pairs of them helps us to find their similarity and derive structural relationship amongst them. For genomic sequences such measures make it possible to construct the evolution tree of…

Information Theory · Computer Science 2012-08-29 Sandeep Hosangadi

3D alignment has become a very important part of 3D scanning technology. For instance, we can divide the alignment process into four steps: key point detection, key point description, initial pose estimation, and alignment refinement.…

Computer Vision and Pattern Recognition · Computer Science 2021-10-29 Abdenour Amamra , Khalid Boumaza

Dense retrieval, which encodes queries and documents into a single dense vector, has become the dominant neural retrieval approach due to its simplicity and compatibility with fast approximate nearest neighbor algorithms. As the tasks dense…

Information Retrieval · Computer Science 2026-02-06 Julian Killingback , Mahta Rafiee , Madine Manas , Hamed Zamani

In many applications, it is necessary to determine the string similarity. Edit distance[WF74] approach is a classic method to determine Field Similarity. A well known dynamic programming algorithm [GUS97] is used to calculate edit distance…

Data Structures and Algorithms · Computer Science 2007-05-23 Qi Xiao Yang , Sung Sam Yuan , Lu Chun , Li Zhao , Sun Peng

Dimensionality reduction (DR) of image features plays an important role in image retrieval and classification tasks. Recently, two types of methods have been proposed to improve the both the accuracy and efficiency for the dimensionality…

Computer Vision and Pattern Recognition · Computer Science 2013-04-10 Yao Nan , Qian Feng , Sun Zuolei

Recurrent neural networks (RNNs) in combination with a pooling operator and the neighbourhood components analysis (NCA) objective function are able to detect the characterizing dynamics of sequences and embed them into a fixed-length vector…

Neural and Evolutionary Computing · Computer Science 2013-08-23 Justin Bayer , Christian Osendorfer , Patrick van der Smagt

We extend an implicit regularization scheme to be applicable in the $n$-dimensional space-time. Within this scheme divergences involving parity violating objects can be consistently treated without recoursing to dimensional continuation.…

High Energy Physics - Theory · Physics 2016-09-06 A. P. B. Scarpelli , M. Sampaio , M. C. Nemes

High-dimensional datasets often contain multiple meaningful clusterings in different subspaces. For example, objects can be clustered either by color, weight, or size, revealing different interpretations of the given dataset. A variety of…

Machine Learning · Computer Science 2025-04-08 Collin Leiber , Dominik Mautz , Claudia Plant , Christian Böhm

In this paper, we present an optical computing method for string data alignment applicable to genome information analysis. By applying moire technique to spatial encoding patterns of deoxyribonucleic acid (DNA) sequences, association…

The main contribution of this dissertation is the introduction of new or improved approximation algorithms and data structures for several similarity search problems. We examine the furthest neighbor query, the annulus query, distance…

Data Structures and Algorithms · Computer Science 2019-06-13 Johan von Tangen Sivertsen

Multidimensional scaling of gene sequence data has long played a vital role in analysing gene sequence data to identify clusters and patterns. However the computation complexities and memory requirements of state-of-the-art dimensional…

Artificial Intelligence · Computer Science 2021-04-20 Pulasthi Wickramasinghe , Geoffrey Fox