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We calculate the fluctuation spectrum of the shape of a lipid vesicle or cell exposed to a nonthermal source of noise. In particular we take into account constraints on the membrane area and the volume of fluid that it encapsulates when…

Soft Condensed Matter · Physics 2013-11-07 Bastien Loubet , Udo Seifert , Michael Andersen Lomholt

Atomic displacements of hydrated proteins are dominated by phonon vibrations at low temperatures and by dissipative large-amplitude motions at high temperatures. A crossover between the two regimes is known as a dynamical transition. Recent…

Biological Physics · Physics 2010-11-05 Dmitry V. Matyushov , Alexander Y. Morozov

We study theoretically the denaturation of single RNA molecules by mechanical stretching, focusing on signatures of the (un)folding pathway in molecular fluctuations. Our model describes the interactions between nucleotides by incorporating…

Soft Condensed Matter · Physics 2009-11-07 Ulrich Gerland , Ralf Bundschuh , Terence Hwa

The denaturation of double-stranded DNA as function of force and temperature is discussed. At room temperature, sequence heterogeneity dominates the physics of single molecule force-extension curves starting about 7 piconewtons of below a…

Condensed Matter · Physics 2007-05-23 David R. Nelson

We study the influence of thermal fluctuations on the buckling behavior of thin elastic capsules with spherical rest shape. Thermal fluctuations affect the buckling instability by two mechanisms. On the one hand, thermal fluctuations can…

Statistical Mechanics · Physics 2018-05-23 Lorenz Baumgarten , Jan Kierfeld

The interplay between bending of the molecule axis and appearance of disruptions in circular DNA molecules, with $\sim 100$ base pairs, is addressed. Three minicircles with different radii and almost equal content of AT and GC pairs are…

Soft Condensed Matter · Physics 2014-06-03 Marco Zoli

A theory for thermomechanical behavior of homogeneous DNA at thermal equilibrium predicts critical temperatures for denaturation under torque and stretch, phase diagrams for stable B--DNA, supercoiling, optimally stable torque, and the…

Soft Condensed Matter · Physics 2015-05-27 Cristiano Nisoli , A. R. Bishop

One of the major functions of RecA protein in the cell is to bind single-stranded DNA exposed upon damage, thereby triggering the SOS repair response.We present fluorescence anisotropy measurements at the binding onset, showing enhanced DNA…

Biological Physics · Physics 2010-08-05 Tsvi Tlusty , Roy Bar-Ziv , Albert Libchaber

A recent experiment [Sadoon AA, Wang Y. 2018 Phys. Rev. E 98, 042411] has revealed that nucleoid associated proteins (i.e., DNA-binding proteins) exhibit highly heterogeneous diffusion processes in bacteria where not only the diffusion…

Statistical Mechanics · Physics 2021-03-09 Yuichi Itto , Christian Beck

Fr\"ohlich discovered the remarkable condensation of polar vibrations into the lowest frequency mode when the system is pumped externally. For a full understanding of the Fr\"ohlich condensate one needs to go beyond the mean field level to…

Quantum Physics · Physics 2019-04-24 Zhedong Zhang , Girish S. Agarwal , Marlan O. Scully

Many biological functions rely on the reshaping of cell membranes, in particular into nanotubes, which are covered in vivo by dynamic actin networks. Nanotubes are subject to thermal fluctuations, but the effect of these on cell functions…

Biological Physics · Physics 2020-12-01 Antoine Allard , Fabrice Valentino , Cécile Sykes , Timo Betz , Clément Campillo

The formation of bubbles in nucleic acids (NAs) are fundamental in many biological processes such as DNA replication, recombination, telomeres formation, nucleotide excision repair, as well as RNA transcription and splicing. These precesses…

Biomolecules · Quantitative Biology 2007-05-23 D. Hennig , J. F. R. Archilla , J. M. Romero

We calculate suppression of inter- and intralayer superconducting currents due to equilibrium phase fluctuations and find that, in contrast to a recent prediction, the effect of thermal fluctuations cannot account for linear temperature…

Superconductivity · Physics 2009-10-31 S. N. Artemenko , S. V. Remizov

We separate double stranded lambda phage DNA by applying a fixed force at a constant temperature ranging from 15C to 50C, and measure the minimum force required to separate the two strands, providing the first experimental determination of…

Soft Condensed Matter · Physics 2009-11-10 C. Danilowicz , Y. Kafri , R. S. Conroy , V. W. Coljee , J. Weeks , M. Prentiss

Charge transport through a short DNA oligomer (Dickerson dodecamer) in presence of structural fluctuations is investigated using a hybrid computational methodology based on a combination of quantum mechanical electronic structure…

Soft Condensed Matter · Physics 2015-05-14 R. Gutierrez , R. Caetano , P. B. Woiczikowski , T. Kubar , M. Elstner , G. Cuniberti

The paper deals with the two-state (opening-closing of base pairs) model used to describe the fluctuation dynamics of a single bubble formation. We present an exact solution for the discrete and finite size version of the model that…

Soft Condensed Matter · Physics 2009-11-10 D. J. Bicout , E. Kats

The instantaneous normal modes corresponding to base pair vibrations (radial modes) and twist angle fluctuations (angular modes) of a DNA molecule model at ambient temperature are theoretically investigated. Due to thermal disorder, normal…

Statistical Mechanics · Physics 2009-10-31 Simona Cocco , Remi Monasson

The occurrence of phase fluctuations due to thermal excitations in Bose-Einstein condensates (BECs) is studied for a variety of temperatures and trap geometries. We observe the statistical nature of the appearence of phase fluctuations and…

Bacteria meticulously regulate their intracellular ion concentrations and create ionic concentration gradients across the bacterial membrane. These ionic concentration gradients provide free energy for many cellular processes and are…

Applied Physics · Physics 2022-07-05 Yichao Yang , Hagen Gress , Kamil L. Ekinci

Membrane shape fluctuations induce attractive interactions between rigid inclusions. Previous analytical studies showed that the fluctuation-induced pair interactions are rather small compared to thermal energies, but also that multi-body…

Soft Condensed Matter · Physics 2009-11-07 Thomas R Weikl
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