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This work investigates the change in cell survival predicted by the local effect model (LEM) for an irradiated cell containing metal nanoparticles (MNPs) depending on the distribution of neighboring cells and the uptake of MNPs into the…

Medical Physics · Physics 2025-10-20 Hans Rabus , Leo Thomas

Induced effects by direct exposure to ionizing radiation (IR) are a central issue in many fields like radiation protection, clinic diagnosis and oncological therapies. Direct irradiation at certain doses induce cell death, but similar…

Subcellular Processes · Quantitative Biology 2015-06-04 G. F. Goya , L. Asin , M. P. Calatayud , A. Tres , M. R. Ibarra

Nanoparticles (NPs) engineered for biomedical applications are meant to be in contact with protein-rich physiological fluids. These proteins are usually adsorbed onto the NP surface, forming a swaddling layer called protein corona that…

Biological Physics · Physics 2014-07-01 M. P. Catalayud , B. Sanz , V. Raffa , C. Riggio , M. R. Ibarra , G. F. Goya

We present a study on the magnetic behavior of dextran-coated magnetite nanoparticles (DM NPs) with sizes between 3 and 19 nm, synthesized by hydrothermal-assisted co-precipitation method. The decrease of saturation magnetization ($M_s$)…

Materials Science · Physics 2023-03-28 Zhila Shaterabadi , Gholamreza Nabiyouni , Gerardo F Goya , Meysam Soleymani

Magnetic fluid hyperthermia (MFH), the procedure of raising the temperature of tumor cells using magnetic nanoparticles (MNPs) as heating agents, has proven successful in treating some types of cancer. However, the low heating power…

Magnetic particle imaging (MPI) is a non-invasive, non-ionizing imaging technique for the visualization and quantification of magnetic nanoparticles (MNPs). The technique is especially suitable for cell imaging as it offers zero background…

The discovery in the early 2000's that magnetic nanoparticles (MNPs) complexed to nonviral or viral vectors can, in the presence of an external magnetic field, greatly enhance gene transfer into cells has raised much interest. This…

Quantitative Methods · Quantitative Biology 2011-11-08 José I. Schwerdt , Gerardo F. Goya , Pilar Calatayud , Claudia B. Hereñú , Paula C. Reggiani , Rodolfo G. Goya

The interaction of magnetic nanoparticles (MNPs) with various magnetic fields could directly induce cellular effects. Many scattered investigations have got involved in these cellular effects, analyzed their relative mechanisms and extended…

Biological Physics · Physics 2017-01-24 Linjie Chen , Changyou Chen , Pingping Wang , Tao Song

This work reports on the synthesis and characterization of a new type of electrospun magnetic nanofibers (MNFs), and their application for degradation of organic pollutants using remote magnetic inductive heating. We describe a simple…

Magnetic nanoparticles (MNPs) are the foundation of several new strategies for neural repair and neurological therapies. The fact that a remote force can act on MNPs at the cytoplasmic space constitutes the essence of many new…

Neurons and Cognition · Quantitative Biology 2024-02-22 Gerardo F. Goya , Vittoria Raffa

Magnetic hyperthermia is currently an EU-approved clinical therapy against tumor cells that uses magnetic nanoparticles under a time varying magnetic field (TVMF). The same basic principle seems promising against trypanosomatids causing…

Biological Physics · Physics 2015-03-13 V. Grazú , A. M. Silber , M. Moros , L. Asín , T. E. Torres , C. Marquina , M. R. Ibarra , G. F. Goya

Magnetic nanoparticles (MNPs) derived from the Massart coprecipitation method have played a pioneering role in bridging materials science and biology. Their magnetic moment and nanoscale dimensions have long enabled applications in magnetic…

Soft Condensed Matter · Physics 2025-12-02 Myriam Reffay , Gilles Tessier , Jean-François Berret

The use of drugs or radiation to attack cancerous cells often leaves the treatment material within the body where it could affect healthy cells or damages healthy tissue; as is the case with traditional invasive surgery. An alternative…

Biological Physics · Physics 2022-06-14 Derek Michael Forrester

Since the last decades, there have been numerous reports about the interaction of magnetic field (MF) and cold atmospheric plasma (CAP) with the biological systems, separately. In this manuscript, we have investigated the combined effect of…

Medical Physics · Physics 2023-08-24 R. Mehrabifard , H. Mehdian , K. Hajisharifi , E. Amini

Due to the potential applications in biomedical engineering, it becomes more and more important to understand the process of engulfment and internalization of nanoparticles (NPs) by cell membranes. Despite the fact that the interaction…

Biological Physics · Physics 2023-12-12 Ke Xiao , Jing Li , Rui Ma , Chen-Xu Wu

Background: Biological effects of extra-low-frequency (ELF) magnetic fields (MF) have lacked a credible mechanism of interaction between MFs and living material. Objectives: Examine the effect of ELF-MFs on cancer cells. Methods: Five…

General Physics · Physics 2012-09-27 Ying Li , Paul Heroux

Exaggerate radical-induced DNA damage under magnetic fields is of great concerns to medical biosafety and to bio-molecular device based upon DNA electronic conductivity. In this report, the effect of applying an external magnetic field (MF)…

Biological Physics · Physics 2015-08-17 Jiun Ru Wong , Kee Jin Lee , Jian-Jun Shu , Fangwei Shao

We report on the uptake, toxicity and degradation of magnetic nanowires by NIH/3T3 mouse fibroblasts. Magnetic nanowires of diameters 200 nm and lengths comprised between 1 {\mu}m and 40 {\mu}m are fabricated by controlled assembly of iron…

Nowadays, there is a growing interest in the field of magnetic particle spectroscopy (MPS)-based bioassays. MPS monitors the dynamic magnetic response of surface-functionalized magnetic nanoparticles (MNPs) upon excitation by an alternating…

Systems and Control · Electrical Eng. & Systems 2022-11-14 Vinit Kumar Chugh , Arturo di Girolamo , Venkatramana D. Krishna , Kai Wu , Maxim C-J Cheeran , Jian-Ping Wang

The influence of an external magnetic field upon the capture of 130 nm magnetic nanoparticles (MNPs) by ferromagnetic nanostructures was investigated. The magnetophoretic forces acting upon a nanoparticle were simulated in external magnetic…

Mesoscale and Nanoscale Physics · Physics 2023-08-25 Reyne Dowling , Mikhail Kostylev
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