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Many biological and artificial transport channels function without direct input of metabolic energy during a transport event and without structural rearrangements involving transitions from a 'closed' to an 'open' state. Nevertheless, such…

Subcellular Processes · Quantitative Biology 2009-11-13 Anton Zilman

Cellular cargo can be bound to cytoskeletal filaments by one or multiple active or passive molecular motors. Recent experiments have shown that the presence of auxiliary, nondriving motors, results in an enhanced processivity of the cargo,…

Biomolecules · Quantitative Biology 2019-03-27 Filippo Posta , Maria R. D'Orsogna , Tom Chou

A molecular motor is made of either a single macromolecule or a macromolecular complex. Just like their macroscopic counterparts, molecular motors "transduce" input energy into mechanical work. All the nano-motors considered here operate…

Biological Physics · Physics 2013-07-18 Debashish Chowdhury

Industrial manipulators do not collapse under their own weight when powered off due to the friction in their joints. Although these mechanism are effective for stiff position control of pick-and-place, they are inappropriate for legged…

Robotics · Computer Science 2020-11-06 Young-woo Sim , Joao Ramos

Biomolecular machines are protein complexes that convert between different forms of free energy. They are utilized in nature to accomplish many cellular tasks. As isothermal nonequilibrium stochastic objects at low Reynolds number, they…

Statistical Mechanics · Physics 2020-01-22 Aidan I Brown , David A Sivak

We review the properties of biological motor proteins which move along linear filaments that are polar and periodic. The physics of the operation of such motors can be described by simple stochastic models which are coupled to a chemical…

Biological Physics · Physics 2009-10-31 Frank Julicher

We introduce a new approach to build microscopic engines on the atomic scale that move translationally or rotationally and can perform useful functions such as pulling of a cargo. Characteristic of these engines is the possibility to…

Condensed Matter · Physics 2009-10-31 Markus Porto , Michael Urbakh , Joseph Klafter

Active matter physics and swarm robotics have provided powerful tools for the study and control of ensembles driven by internal sources. At the macroscale, controlling swarms typically utilizes significant memory, processing power, and…

The pump process of the ratchet model inspired by the $F_o$ rotatory motor of ATP synthase is investigated. In this model there are two kinds of characteristic time. One is dynamical, the relaxation time of the system. Others are chemical,…

Biological Physics · Physics 2007-05-23 Hiroshi Miki , Masatoshi Sato , Mahito Kohmoto

In systems possessing spatial or dynamical symmetry breaking, Brownian motion combined with symmetric external input signals, deterministic or random, alike, can assist directed motion of particles at the submicron scales. In such cases,…

Statistical Mechanics · Physics 2009-06-05 Peter Hanggi , Fabio Marchesoni

The efficiency at maximum power (EMP) for tight-coupling molecular motors is investigated within the framework of irreversible thermodynamics. It is found that the EMP depends merely on the constitutive relation between the thermodynamic…

Statistical Mechanics · Physics 2013-12-13 Z. C. Tu

At electromagnetic interactions of particles there arises defect of masses, i.e. the energy is liberated since the particles of the different charges are attracted. It is shown that this change of the effective mass of a particle in the…

Quantum Physics · Physics 2007-05-23 Kh. M. Beshtoev

We examine the stochastic dynamics of two enzymes that are mechanically coupled to each other, e.g., through an elastic substrate or a fluid medium. The enzymes undergo conformational changes during their catalytic cycle, which itself is…

Statistical Mechanics · Physics 2021-11-16 Jaime Agudo-Canalejo , Tunrayo Adeleke-Larodo , Pierre Illien , Ramin Golestanian

Many biological functions are executed by molecular machines, which consume energy and convert it into mechanical work. Biological machines have evolved to transport cargo, facilitate folding of proteins and RNA, remodel chromatin and…

Biological Physics · Physics 2020-04-15 Mauro L. Mugnai , Changbong Hyeon , Michael Hinczewski , D. Thirumalai

The dynamics of spherical particles driven along an interface between two immiscible fluids is investigated asymptotically. Under the assumptions of a pinned three-phase contact line and very different viscosities of the two fluids, a…

Soft Condensed Matter · Physics 2015-04-01 Aaron Dörr , Steffen Hardt

Molecular dynamics simulations are an important tool for describing the evolution of a chemical system with time. However, these simulations are inherently held back either by the prohibitive cost of accurate electronic structure theory…

Chemical Physics · Physics 2018-12-20 Michael Gastegger , Philipp Marquetand

We propose a model for a molecular motor in a molecular electronic junction driven by a natural manifestation of Landauer's blowtorch effect. The effect emerges via the interplay of the electronic friction and diffusion coefficients, each…

Mesoscale and Nanoscale Physics · Physics 2023-06-21 Riley J. Preston , Daniel S. Kosov

We discuss the appareance of ordered structures in assemblies of magnetic particles. The phenomenon occurs when dipolar interactions and the thermal motion of the particles compete, and is mediated by screening and excluded volume effects.…

Soft Condensed Matter · Physics 2009-10-31 R. Pastor-Satorras , J. M. Rubi

Rectification of interacting Brownian particles is investigated in a two-dimensional asymmetric channel in the presence of an external periodic driving force. The periodic driving force can break the thermodynamic equilibrium and induces…

Soft Condensed Matter · Physics 2021-07-19 Narender Khatri , P. S. Burada

Bacteria can adjust the structure of colonies and biofilms to enhance their survival rate under external stress. Here, we explore the link between bacterial interaction forces and colony structure. We show that the activity of extracellular…