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The traffic of molecular motors which interact through mutual exclusion is studied theoretically for half-open tube-like compartments. These half-open tubes mimic the shapes of axons. The mutual exclusion leads to traffic jams or density…

Statistical Mechanics · Physics 2007-05-23 Melanie J. I. Muller , Stefan Klumpp , Reinhard Lipowsky

Molecular motors transport various cargos along cytoskeletal filaments, analogous to trucks on roads. In contrast to vehicles, however, molecular motors do not work alone but in small teams. We describe a simple model for the transport of a…

Statistical Mechanics · Physics 2008-07-08 Melanie J. I. Müller , Janina Beeg , Rumiana Dimova , Stefan Klumpp , Reinhard Lipowsky

By conditioning a stochastic process on the value of an observable, one obtains a new stochastic process with different properties. We apply this idea in the context of active matter, and condition interacting self-propelled particles on…

Statistical Mechanics · Physics 2020-03-04 Francesco Cagnetta , Emil Mallmin

Molecular motors power directed transport of cargoes within cells. Even if a single motor is sufficient to transport a cargo, motors often cooperate in small teams. We discuss the cooperative cargo transport by several motors theoretically…

Subcellular Processes · Quantitative Biology 2007-05-23 Stefan Klumpp , Melanie J. I. Muller , Reinhard Lipowsky

Recent experiments reveal both passive subdiffusion of various nanoparticles and anomalous active transport of such particles by molecular motors in the molecularly crowded environment of living biological cells. Passive and active…

Biological Physics · Physics 2014-03-24 Igor Goychuk , Vasyl O. Kharchenko , R. Metzler

Dynamic properties of molecular motors that fuel their motion by actively interacting with underlying molecular tracks are studied theoretically via discrete-state stochastic ``burnt-bridge'' models. The transport of the particles is viewed…

Soft Condensed Matter · Physics 2009-11-13 Maxim N. Artyomov , Alexander Yu. Morozov , Ekaterina Pronina , Anatoly B. Kolomeisky

We study effective three-particle interactions between valence electrons, which are induced by the core polarization. Such interactions are enhanced when valence orbitals have strong overlap with the outermost core shell, in particular for…

Atomic Physics · Physics 2016-09-28 M. G. Kozlov , M. S. Safronova , S. G. Porsev , I. I. Tupitsyn

The energetics and efficiency of a linear molecular motor model proposed by Mogilner et al. (Phys. Lett. 237, 297 (1998)) is analyzed from an analytical point of view. The model which is based on protein friction with a track is described…

Statistical Mechanics · Physics 2014-10-07 Hans C. Fogedby , Axel Svane

We discuss effects of the stepping kinetics of molecular motors on their traffic behavior on crowded filaments using a simple two-state chemomechanical cycle. While the general traffic behavior is quite robust with respect to the detailed…

Statistical Mechanics · Physics 2008-10-10 Stefan Klumpp , Yan Chai , Reinhard Lipowsky

The stochastic driving force exerted by a single molecular motor (e.g., a kinesin, or myosin) moving on a periodic molecular track (microtubule, actin filament, etc.) is discussed from a general viewpoint open to experimental test. An…

Statistical Mechanics · Physics 2009-10-31 Michael E. Fisher , Anatoly B. Kolomeisky

The collective dynamics of $N$ weakly coupled processive molecular motors are considered theoretically. We show, using a discrete lattice model, that the velocity-force curves strongly depend on the effective dynamic interactions between…

Subcellular Processes · Quantitative Biology 2009-11-11 O. Campas , Y. Kafri , K. B. Zeldovich , J. Casademunt , J. -F. Joanny

Novel organic materials formed from functional molecules are attractive for various nanoelectronic applications because they are environmentally friendly, widely available and inexpensive. Recent advancement in bottom-up fabrication methods…

Mesoscale and Nanoscale Physics · Physics 2022-12-14 Abdalghani Daaoub , Renhang Wang , Ross Davidson , Sara Sangtarash , Hatef Sadeghi

Active systems are inherently out of equilibrium, as they collect energy from their surroundings and transform it into directed motion. A recent theoretical study suggests that binary mixtures of active particles with distinct effective…

Soft Condensed Matter · Physics 2017-11-22 Sunita Kumari , Andre S. Nunes , Nuno A. M. Araujo , Margarida Telo da Gama

Biological molecular motors are high-performance nanomachines that convert chemical energy into mechanical motion via chemomechanical coupling. Their reaction cycles typically comprise a series of intermediate chemical states between the…

Biological Physics · Physics 2025-05-26 Akihiro Fukuda , Yohei Nakayama , Shoichi Toyabe

We study motor traffic on Bethe networks subject to hard-core exclusion for both tightly coupled one-state machines and loosely coupled two-state machines that perform work against a constant load. In both cases we find an…

Statistical Mechanics · Physics 2015-06-18 Natalia Golubeva , Alberto Imparato

We consider a molecular machine described as a Brownian particle diffusing in a tilted periodic potential. We evaluate the absorbed and released power of the machine as a function of the applied molecular and chemical forces, by using the…

Statistical Mechanics · Physics 2012-03-23 N. Golubeva , A. Imparato , L. Peliti

We consider the motion of a finite though large number of particles in the whole space R n. Particles move freely until they experience pairwise collisions. We use our recent theory of divergence-controlled positive symmetric tensors in…

Analysis of PDEs · Mathematics 2019-03-15 Denis Serre

Starting from a microscopic model for a spherically symmetric active Janus particle, we study the interactions between two such active motors. The ambient fluid mediates a long range hydrodynamic interaction between two motors. This…

Soft Condensed Matter · Physics 2021-11-17 Parvin Bayati , Ali Najafi

At molecular scales, fluctuations play a significant role and prevent biomolecular processes from always proceeding in a preferred direction, raising the question of how limited amounts of free energy can be dissipated to obtain directed…

Statistical Mechanics · Physics 2016-10-05 Aidan I. Brown , David A. Sivak

The transport of cargo particles which are pulled by several molecular motors in a cooperative manner is studied theoretically. The transport properties depend primarily on the maximal number, $N$, of motor molecules that may pull…

Subcellular Processes · Quantitative Biology 2007-05-23 Stefan Klumpp , Reinhard Lipowsky