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The thermodynamic uncertainty relation provides an inequality relating any mean current, the associated dispersion and the entropy production rate for arbitrary non-equilibrium steady states. Applying it here to a general model of a…

Statistical Mechanics · Physics 2017-01-05 Patrick Pietzonka , Andre C. Barato , Udo Seifert

In a single molecule assay, the motion of a molecular motor is often inferred from measuring the stochastic trajectory of a large probe particle attached to it. We discuss a simple model for this generic set-up taking into account…

Statistical Mechanics · Physics 2012-11-22 Eva Zimmermann , Udo Seifert

The effect of interactions on dynamics of coupled motor proteins is investigated theoretically. A simple stochastic discrete model, that allows to calculate explicitly the dynamic properties of the system, is developed. It is shown that…

Soft Condensed Matter · Physics 2009-11-11 Evgeny B. Stukalin , Anatoly B. Kolomeisky

Biological functions in each animal cell depend on coordinated operations of a wide variety of molecular motors. Some of the these motors transport cargo to their respective destinations whereas some others are mobile workshops which…

Biological Physics · Physics 2008-03-07 Debashish Chowdhury

Molecular motors play pivotal roles in organizing the interior of cells. A motor efficient in cargo transport would move along cytoskeletal filaments with a high speed and a minimal error in transport distance (or time) while consuming a…

Biological Physics · Physics 2019-06-07 Wonseok Hwang , Changbong Hyeon

Biological molecular machines are enzymes that simultaneously catalyze two processes, one donating free energy and second accepting it. Recent studies show that most native protein enzymes have a rich stochastic dynamics that often…

Biological Physics · Physics 2018-12-21 Michal Kurzynski , Przemyslaw Chelminiak

Physics students now have access to interactive molecular dynamics simulations that can model and animate the motions of hundreds of particles, such as noble gas atoms, that attract each other weakly at short distances but repel strongly…

Physics Education · Physics 2015-02-27 Daniel V. Schroeder

Because of its nonequilibrium character, active matter in a steady state can drive engines that autonomously deliver work against a constant mechanical force or torque. As a generic model for such an engine, we consider systems that contain…

Statistical Mechanics · Physics 2019-11-15 Patrick Pietzonka , Étienne Fodor , Christoph Lohrmann , Michael E. Cates , Udo Seifert

Molecular motors perform active movements along cytoskeletal filaments and drive the traffic of organelles and other cargo particles in cells. In contrast to the macroscopic traffic of cars, however, the traffic of molecular motors is…

Statistical Mechanics · Physics 2009-12-04 Stefan Klumpp , Melanie J. I. Müller , Reinhard Lipowsky

Processive molecular motors which drive the traffic of organelles in cells move in a directed way along cytoskeletal filaments. On large time scales, they perform motor walks, i.e., peculiar random walks which arise from the repeated…

Statistical Mechanics · Physics 2007-05-23 Stefan Klumpp , Theo M. Nieuwenhuizen , Reinhard Lipowsky

Living systems efficiently use chemical fuel to do work, process information, and assemble patterns despite thermal noise. Whether high efficiency arises from general principles or specific fine-tuning is unknown. Here, applying a recent…

Biological Physics · Physics 2022-10-11 Milo M Lin

Study on a rectified current induced by active particles has received a great attention due to its possible application to a microscopic motor in biological environments. Insertion of an {\em asymmetric} passive object amid many active…

Soft Condensed Matter · Physics 2021-11-19 Jae Sung Lee , Jong-Min Park , Jae Dong Noh , Hyunggyu Park

We study a one-dimensional mixture of active (run-and-tumble) particles and passive (Brownian) particles, with single-file constraint, in a sawtooth potential. The active particles experience a ratchet effect: this generates a current,…

Statistical Mechanics · Physics 2023-09-01 Jean-François Derivaux , Robert L. Jack , Michael E. Cates

We examine the dependence of the physical quantities of the rotatory molecular motor, such as the rotation velocity and the proton translocation rate, on the chemical reaction rate using the model based only on diffusion process. A peculiar…

Biological Physics · Physics 2009-11-10 Hiroshi Miki , Masatoshi Sato , Mahito Kohmoto

The motion of molecules across channels is critically important for understanding mechanisms of cellular processes. Here we investigate the mechanism of interactions in the molecular transport by analyzing exactly solvable discrete…

Soft Condensed Matter · Physics 2015-05-18 Anatoly B. Kolomeisky , Karthik Uppulury

Molecular motors interacting with cytoskeletal filaments undergo peculiar random walks consisting of alternating sequences of directed movements along the filaments and diffusive motion in the surrounding solution. An ensemble of motors is…

Statistical Mechanics · Physics 2007-05-23 Theo M. Nieuwenhuizen , Stefan Klumpp , Reinhard Lipowsky

Active particles contain internal degrees of freedom with the ability to take in and dissipate energy and, in the process, execute systematic movement. Examples include all living organisms and their motile constituents such as molecular…

Soft Condensed Matter · Physics 2015-05-18 Sriram Ramaswamy

Particularly for aneutronic fusion schemes, it is advantageous to manipulate the fuel species differently from one another, as well as expel ash promptly. The ponderomotive effect can be used to selectively manipulate particles. It is…

Plasma Physics · Physics 2025-02-05 Tal Rubin , Nathaniel J. Fisch

Three problems in the statistical mechanics of models for an assembly of molecular motors interacting with cytoskeletal filaments are reviewed. First, a description of the hydrodynamical behaviour of density-density correlations in…

Statistical Mechanics · Physics 2009-11-11 Gautam I. Menon

Understanding the operation of biological molecular motors, nanoscale machines that transduce electrochemical energy into mechanical work, is enhanced by bottom-up strategies to synthesize novel motors.

Biological Physics · Physics 2017-05-15 Chapin Korosec , Nancy R. Forde