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Protein-protein interaction (PPI) network alignment is a canonical operation to transfer biological knowledge among species. The alignment of PPI-networks has many applications, such as the prediction of protein function, detection of…

Molecular Networks · Quantitative Biology 2019-05-15 Ehsan Kazemi , Matthias Grossglauser

We formulate an info-clustering paradigm based on a multivariate information measure, called multivariate mutual information, that naturally extends Shannon's mutual information between two random variables to the multivariate case…

Information Theory · Computer Science 2016-12-13 Chung Chan , Ali Al-Bashabsheh , Qiaoqiao Zhou , Tarik Kaced , Tie Liu

This paper presents new and effective algorithms for learning kernels. In particular, as shown by our empirical results, these algorithms consistently outperform the so-called uniform combination solution that has proven to be difficult to…

Machine Learning · Computer Science 2024-05-01 Corinna Cortes , Mehryar Mohri , Afshin Rostamizadeh

Information-theoretic quantities, such as conditional entropy and mutual information, are critical data summaries for quantifying uncertainty. Current widely used approaches for computing such quantities rely on nearest neighbor methods and…

Conventional multimodal alignment methods assume mutual redundancy across all modalities, an assumption that fails in real-world distributed scenarios. We propose SheafAlign, a sheaf-theoretic framework for decentralized multimodal…

Machine Learning · Computer Science 2025-10-24 Abdulmomen Ghalkha , Zhuojun Tian , Chaouki Ben Issaid , Mehdi Bennis

The recent developments in machine learning have highlighted a conflict between online platforms and their users in terms of privacy. The importance of user privacy and the struggle for power over user data has been intensified as…

Machine Learning · Computer Science 2026-03-09 Charles Meyers , Aaron MacSween , Erik Elmroth , Tommy Löfstedt

Mutual information (MI) is a fundamental measure of statistical dependence, with a myriad of applications to information theory, statistics, and machine learning. While it possesses many desirable structural properties, the estimation of…

Information Theory · Computer Science 2021-10-19 Ziv Goldfeld , Kristjan Greenewald

Since its introduction in 2011, the partial information decomposition (PID) has triggered an explosion of interest in the field of multivariate information theory and the study of emergent, higher-order ("synergistic") interactions in…

Information Theory · Computer Science 2024-02-14 Thomas F. Varley

Statistically sound crystallographic symmetry classifications are obtained with information theory based methods in the presence of approximately Gaussian distributed noise. A set of three synthetic images with very strong Fedorov type…

Image and Video Processing · Electrical Eng. & Systems 2023-03-28 Peter Moeck

As one of the central tasks in machine learning, regression finds lots of applications in different fields. An existing common practice for solving regression problems is the mean square error (MSE) minimization approach or its regularized…

Machine Learning · Statistics 2022-11-24 Jirong Yi , Qiaosheng Zhang , Zhen Chen , Qiao Liu , Wei Shao , Yusen He , Yaohua Wang

In many problems in data mining and machine learning, data items that need to be clustered or classified are not points in a high-dimensional space, but are distributions (points on a high dimensional simplex). For distributions, natural…

Data Structures and Algorithms · Computer Science 2007-07-13 Sudipto Guha , Andrew McGregor , Suresh Venkatasubramanian

Sliced mutual information (SMI) is defined as an average of mutual information (MI) terms between one-dimensional random projections of the random variables. It serves as a surrogate measure of dependence to classic MI that preserves many…

Information Theory · Computer Science 2022-10-18 Ziv Goldfeld , Kristjan Greenewald , Theshani Nuradha , Galen Reeves

Imputation of missing data is a common application in various classification problems where the feature training matrix has missingness. A widely used solution to this imputation problem is based on the lazy learning technique, $k$-nearest…

Machine Learning · Statistics 2020-02-26 Arkopal Choudhury , Michael R. Kosorok

$K$-NN classifier is one of the most famous classification algorithms, whose performance is crucially dependent on the distance metric. When we consider the distance metric as a parameter of $K$-NN, learning an appropriate distance metric…

Machine Learning · Computer Science 2019-11-26 Kun Song

The estimation of mutual information (MI) or conditional mutual information (CMI) from a set of samples is a long-standing problem. A recent line of work in this area has leveraged the approximation power of artificial neural networks and…

Information Theory · Computer Science 2021-10-27 Sina Molavipour , Germán Bassi , Mikael Skoglund

Mutual Information (MI) is a fundamental measure of statistical dependence widely used in representation learning. While direct optimization of MI via its definition as a Kullback-Leibler divergence (KLD) is often intractable, many recent…

Machine Learning · Computer Science 2026-03-18 Reuben Dorent , Polina Golland , William Wells

We theorize that phylogenetic profiles provide a quantitative method that can relate the structural and functional properties of proteins, as well as their evolutionary relationships. A key feature of phylogenetic profiles is the…

Quantitative Methods · Quantitative Biology 2009-11-04 Yoojin Hong , Jaewoo Kang , Dongwon Lee , Randen L. Patterson , Damian B. van Rossum

Recently, substantial research efforts in Deep Metric Learning (DML) focused on designing complex pairwise-distance losses, which require convoluted schemes to ease optimization, such as sample mining or pair weighting. The standard…

Machine Learning · Computer Science 2021-11-29 Malik Boudiaf , Jérôme Rony , Imtiaz Masud Ziko , Eric Granger , Marco Pedersoli , Pablo Piantanida , Ismail Ben Ayed

Shannon information (SI) and its special case, divergence, are defined for a DNA sequence in terms of probabilities of chemical words in the sequence and are computed for a set of complete genomes highly diverse in length and composition.…

Genomics · Quantitative Biology 2009-11-10 Hong-Da Chen , Chang-Heng Chang , Li-Ching Hsieh , Hoong-Chien Lee

One of the main problems that emerges in the classic approach to semantics is the difficulty in acquisition and maintenance of ontologies and semantic annotations. On the other hand, the Internet explosion and the massive diffusion of…

Artificial Intelligence · Computer Science 2017-01-12 Valentina Franzoni
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