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In this paper, we present an optical computing method for string data alignment applicable to genome information analysis. By applying moire technique to spatial encoding patterns of deoxyribonucleic acid (DNA) sequences, association…

This paper presents a novel approach to machine learning algorithm design based on information theory, specifically mutual information (MI). We propose a framework for learning and representing functional relationships in data using…

Machine Learning · Computer Science 2024-09-24 Jeremy Nixon

Quantifying the dependence between high-dimensional random variables is central to statistical learning and inference. Two classical methods are canonical correlation analysis (CCA), which identifies maximally correlated projected versions…

Machine Learning · Computer Science 2023-09-29 Dor Tsur , Ziv Goldfeld , Kristjan Greenewald

We present a new method for clustering based on compression. The method doesn't use subject-specific features or background knowledge, and works as follows: First, we determine a universal similarity distance, the normalized compression…

Computer Vision and Pattern Recognition · Computer Science 2007-05-23 Rudi Cilibrasi , Paul Vitanyi

We have developed an alignment-free method that calculates phylogenetic distances using a maximum likelihood approach for a model of sequence change on patterns that are discovered in unaligned sequences. To evaluate the phylogenetic…

Quantitative Methods · Quantitative Biology 2007-05-23 Michael Höhl , Isidore Rigoutsos , Mark A. Ragan

The problem of similarity search is one of the main problems in computer science. This problem has many applications in text-retrieval, web search, computational biology, bioinformatics and others. Similarity between two data objects can be…

Neural and Evolutionary Computing · Computer Science 2013-12-06 Muhammad Marwan Muhammad Fuad

Background: Coevolution within a protein family is often predicted using statistics that measure the degree of covariation between positions in the protein sequence. Mutual Information is a measure of dependence between two random variables…

Populations and Evolution · Quantitative Biology 2013-04-17 Russell J. Dickson , Gregory B. Gloor

In the field of biological research, it is essential to comprehend the characteristics and functions of molecular sequences. The classification of molecular sequences has seen widespread use of neural network-based techniques. Despite their…

Machine Learning · Computer Science 2024-02-14 Sarwan Ali , Tamkanat E Ali , Prakash Chourasia , Murray Patterson

Imitation learning algorithms have been interpreted as variants of divergence minimization problems. The ability to compare occupancy measures between experts and learners is crucial in their effectiveness in learning from demonstrations.…

Machine Learning · Computer Science 2022-07-05 Georgios Papagiannis , Yunpeng Li

Adjusted for chance measures are widely used to compare partitions/clusterings of the same data set. In particular, the Adjusted Rand Index (ARI) based on pair-counting, and the Adjusted Mutual Information (AMI) based on Shannon information…

Machine Learning · Statistics 2015-12-07 Simone Romano , Nguyen Xuan Vinh , James Bailey , Karin Verspoor

Providing natural language-based explanations to justify recommendations helps to improve users' satisfaction and gain users' trust. However, as current explanation generation methods are commonly trained with an objective to mimic existing…

Information Retrieval · Computer Science 2024-08-22 Yurou Zhao , Yiding Sun , Ruidong Han , Fei Jiang , Lu Guan , Xiang Li , Wei Lin , Weizhi Ma , Jiaxin Mao

Massively parallel sequencing techniques have revolutionized biological and medical sciences by providing unprecedented insight into the genomes of humans, animals, and microbes. Modern sequencing platforms generate enormous amounts of…

The scarcity of labeled data often impedes the application of deep learning to the segmentation of medical images. Semi-supervised learning seeks to overcome this limitation by exploiting unlabeled examples in the learning process. In this…

Computer Vision and Pattern Recognition · Computer Science 2021-06-25 Jizong Peng , Marco Pedersoli , Christian Desrosiers

Multiple sequence alignment is a basic procedure in molecular biology, and it is often treated as being essentially a solved computational problem. However, this is not so, and here I review the evidence for this claim, and outline the…

Populations and Evolution · Quantitative Biology 2018-08-24 David A. Morrison

Distance based algorithms are a common technique in the construction of phylogenetic trees from taxonomic sequence data. The first step in the implementation of these algorithms is the calculation of a pairwise distance matrix to give a…

Populations and Evolution · Quantitative Biology 2007-05-23 J G Sumner , P D Jarvis

The ability to compress observational data and accurately estimate physical parameters relies heavily on informative summary statistics. In this paper, we introduce the use of mutual information (MI) as a means of evaluating the quality of…

Cosmology and Nongalactic Astrophysics · Physics 2023-07-12 Ce Sui , Xiaosheng Zhao , Tao Jing , Yi Mao

Deep learning systems have been reported to acheive state-of-the-art performances in many applications, and one of the keys for achieving this is the existence of well trained classifiers on benchmark datasets which can be used as backbone…

Machine Learning · Computer Science 2022-10-04 Jirong Yi , Qiaosheng Zhang , Zhen Chen , Qiao Liu , Wei Shao

Multiple sequence alignment is increasingly important to bioinformatics, with several applications ranging from phylogenetic analyses to domain identification. There are several ways to perform multiple sequence alignment, an important way…

Computational Engineering, Finance, and Science · Computer Science 2015-09-14 Ravi Kumar Yadav Dega , Gunes Ercal

The Mutual Information (MI) is an often used measure of dependency between two random variables utilized in information theory, statistics and machine learning. Recently several MI estimators have been proposed that can achieve parametric…

Information Theory · Computer Science 2018-11-26 Morteza Noshad , Yu Zeng , Alfred O. Hero

In the procedure of constraining the cosmological parameters with the observational Hubble data and the type Ia supernova data, the combination of Masked Autoregressive Flow and Denoising Autoencoder can perform a good result. The above…

Cosmology and Nongalactic Astrophysics · Physics 2023-03-22 Jie-Feng Chen , Yu-Chen Wang , Tingting Zhang , Tong-Jie Zhang