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The function of the organism hinges on the performance of its information-processing networks, which convey information via molecular recognition. Many paths within these networks utilize molecular codebooks, such as the genetic code, to…

Biomolecules · Quantitative Biology 2010-07-27 Tsvi Tlusty

We discuss, in terms of rate-distortion theory, the fitness of molecular codes as the problem of designing an optimal information channel. The fitness is governed by an interplay between the cost and quality of the channel, which induces…

Molecular Networks · Quantitative Biology 2010-07-26 Tsvi Tlusty

Life relies on the efficient performance of molecular codes, which relate symbols and meanings via error-prone molecular recognition. We describe how optimizing a code to withstand the impact of molecular recognition noise may be…

Quantitative Methods · Quantitative Biology 2010-07-26 Tsvi Tlusty

Molecular communication is a biologically-inspired method of communication with attractive properties for microscale and nanoscale devices. In molecular communication, messages are transmitted by releasing a pattern of molecules at a…

Information Theory · Computer Science 2008-12-09 Andrew W. Eckford

Molecular recognition, which is essential in processing information in biological systems, takes place in a crowded noisy biochemical environment and requires the recognition of a specific target within a background of various similar…

Biomolecules · Quantitative Biology 2010-07-27 Yonatan Savir , Tsvi Tlusty

We consider the problem of the evolution of a code within a structured population of agents. The agents try to maximise their information about their environment by acquiring information from the outputs of other agents in the population. A…

Multiagent Systems · Computer Science 2015-05-18 Andres C. Burgos , Daniel Polani

The genetic code maps the sixty-four nucleotide triplets (codons) to twenty amino-acids. Some argue that the specific form of the code with its twenty amino-acids might be a 'frozen accident' because of the overwhelming effects of any…

Quantitative Methods · Quantitative Biology 2010-07-26 Tsvi Tlusty

This article examines recent research in molecular communications from a telecommunications system design perspective. In particular, it focuses on channel models and state-of-the-art physical layer techniques. The goal is to provide a…

Emerging Technologies · Computer Science 2015-07-28 Weisi Guo , Taufiq Asyhari , Nariman Farsad , H. Birkan Yilmaz , Bin Li , Andrew Eckford , Chan-Byoung Chae

Cells are often considered input-output devices that maximize the transmission of information by converting extracellular stimuli (input) via signaling pathways (communication channel) to cell behavior (output). However, in biological…

Cell Behavior · Quantitative Biology 2019-11-04 Gabriele Micali , Robert G. Endres

The genetic code maps the sixty-four nucleotide triplets (codons) to twenty amino-acids. While the biochemical details of this code were unraveled long ago, its origin is still obscure. We review information-theoretic approaches to the…

Genomics · Quantitative Biology 2010-07-23 Tsvi Tlusty

Why do neurons encode information the way they do? Normative answers to this question model neural activity as the solution to an optimisation problem; for example, the celebrated efficient coding hypothesis frames neural activity as the…

Neurons and Cognition · Quantitative Biology 2026-03-06 William Dorrell , Peter E. Latham , James Whittington

This paper studies the stability of communication protocols that deal with transmission errors. We consider a coordination game between an informed sender and an uninformed decision maker, the receiver, who communicate over a noisy channel.…

Computer Science and Game Theory · Computer Science 2015-01-07 Penelope Hernandez , Bernhard von Stengel

We consider distributed computations between two parties carried out over a noisy channel that may erase messages. Following a noise model proposed by Dani et al. (2018), the noise level observed by the parties during the computation in our…

Data Structures and Algorithms · Computer Science 2019-09-17 Ran Gelles , Siddharth Iyer

Information transmission in biological signaling circuits has often been described using the metaphor of a noise filter. Cellular systems need accurate, real-time data about their environmental conditions, but the biochemical reaction…

Molecular Networks · Quantitative Biology 2019-02-27 David Hathcock , James Sheehy , Casey Weisenberger , Efe Ilker , Michael Hinczewski

In diffusion-based molecular communication, information particles locomote via a diffusion process, characterized by random movement and heavy tail distribution for the random arrival time. As a result, the molecular communication shows…

Emerging Technologies · Computer Science 2017-04-05 Changmin Lee , H. Birkan Yilmaz , Chan-Byoung Chae , Nariman Farsad , Andrea Goldsmith

Two new asynchronous modulation techniques for molecular timing (MT) channels are proposed. One based on modulating information on the time between two consecutive releases of indistinguishable information particles, and one based on using…

Signal Processing · Electrical Eng. & Systems 2018-12-12 Nariman Farsad , Yonathan Murin , Weisi Guo , Chan-Byoung Chae , Andrew Eckford , Andrea Goldsmith

For reliable transmission across a noisy communication channel, classical results from information theory show that it is asymptotically optimal to separate out the source and channel coding processes. However, this decomposition can fall…

Machine Learning · Computer Science 2019-05-15 Kristy Choi , Kedar Tatwawadi , Aditya Grover , Tsachy Weissman , Stefano Ermon

In this paper, a simple memory limited transmitter for molecular communication is proposed, in which information is encoded in the diffusion rate of the molecules. Taking advantage of memory, the proposed transmitter reduces the ISI problem…

Information Theory · Computer Science 2014-10-30 Mohammad Movahednasab , Mehdi Soleimanifar , Amin Gohari , Masoumeh Nasiri Kenari , Urbashi Mitra

Optimal transport has numerous applications, particularly in machine learning tasks involving generative models. In practice, the transportation process often encounters an information bottleneck, typically arising from the conversion of a…

Information Theory · Computer Science 2024-12-30 Xiqiang Qu , Ruibin Li , Jun Chen , Lei Yu , Xinbing Wang

A diffusion molecular channel is a channel with memory, as molecules released into the medium hit the receptors after a random delay. Coding over the diffusion channel is performed by choosing the type, intensity, or the released time of…

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