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Morphologies of a vesicle confined in a spherical vesicle were explored experimentally by fast confocal laser microscopy and numerically by a dynamically-triangulated membrane model with area-difference elasticity. The confinement was found…

Soft Condensed Matter · Physics 2014-04-08 Ai Sakashita , Masayuki Imai , Hiroshi Noguchi

We study the phase separation of binary lipid mixtures that form bicontinuous cubic phases. The competition between non-uniform Gaussian membrane curvature and line tension leads to a very rich phase diagram, where we observe symmetry…

Soft Condensed Matter · Physics 2016-08-24 Fabien Paillusson , Matthew R. Pennington , Halim Kusumaatmaja

A model of lipid bilayers made of a mixture of two lipids with different average compositions on both leaflets, is developed. A Landau hamiltonian describing the lipid-lipid interactions on each leaflet, with two lipidic fields $\psi_1$ and…

Soft Condensed Matter · Physics 2014-08-28 Guillaume Gueguen , Nicolas Destainville , Manoel Manghi

The conformation and the phase diagram of a membrane protein are investigated via grand canonical ensemble approach using a homopolymer model. We discuss the nature and pathway of $\alpha$-helix integration into the membrane that results…

Soft Condensed Matter · Physics 2009-10-31 Pyeong Jun Park , W. Sung

In clathrin-mediated endocytosis (CME), clathrin and various adaptor proteins coat a patch of the plasma membrane, which is reshaped to form a budded vesicle. Experimental studies have demonstrated that elevated membrane tension can inhibit…

Biological Physics · Physics 2016-05-04 Julian E. Hassinger , George Oster , David G. Drubin , Padmini Rangamani

Biological membranes typically contain a large number of different components dispersed in small concentrations in the main membrane phase, including proteins, sugars, and lipids of varying geometrical properties. Most of these components…

Soft Condensed Matter · Physics 2018-10-17 Tine Curk , Peter Wirnsberger , Jure Dobnikar , Daan Frenkel , Andela Saric

Topological insulators are materials where current does not flow through the bulk, but along the boundaries, only. They are of particular practical importance, since it is considerably more difficult, by ``conventional'' means, to affect…

Strongly Correlated Electrons · Physics 2021-07-20 Stam Nicolis

Tubular and membranous shapes display a wide range of morphologies that are difficult to analyze within a common framework. By generalizing the classical Helfrich energy of biomembranes, we model them as solutions to a curvature…

Quantitative Methods · Quantitative Biology 2021-03-10 Anna Song

It has been considered that the effective bending rigidity of fluid membranes should be reduced by thermal undulations. However, recent thorough investigation by Pinnow and Helfrich revealed significance of measure factors for the partition…

Condensed Matter · Physics 2009-11-07 Yoshihiro Nishiyama

In this Letter, we use a model fluid mechanics experiment to elucidate the impact of curvature heterogeneities on two-dimensional fields deriving from harmonic potential functions. This result is directly relevant to explain the smooth…

Soft Condensed Matter · Physics 2023-09-08 Stéphane Guillet , Benjamin Guiselin , Mariem Boughzala , Vassili Desages , Denis Bartolo

The fluctuations of two-dimensional extended objects membranes is a rich and exciting field with many solid results and a wide range of open issues. We review the distinct universality classes of membranes, determined by the local order,…

Soft Condensed Matter · Physics 2014-10-13 Mark J. Bowick , Alex Travesset

The adhesion of biological membranes is mediated by the binding of membrane-anchored receptor and ligand proteins. Central questions are how the binding kinetics of these proteins is affected by the membranes and by the membrane anchoring…

Biomolecules · Quantitative Biology 2015-11-30 Jinglei Hu , Guang-Kui Xu , Reinhard Lipowsky , Thomas R. Weikl

We present a theory that combines the framework of irreversible thermodynamics with modified integral theorems to model arbitrarily curved and deforming membranes immersed in bulk fluid solutions. We study the coupling between the mechanics…

Soft Condensed Matter · Physics 2025-09-29 Ahmad M. Alkadri , Kranthi K. Mandadapu

Bending the edge of a thin elastic material promotes rigidity far from its clamped boundary. However, this curvature-induced rigidity can be overwhelmed by gravity or other external loading, resulting in elastic buckling and large…

Soft Condensed Matter · Physics 2025-04-16 Hanzhang Mao , Thomas G. J. Chandler , Mark Han , Saverio E. Spagnolie

Shear-flow-induced structure formation in surfactant-water mixtures is investigated numerically using a meshless-membrane model in combination with a particle-based hydrodynamics simulation approach for the solvent. At low shear rates,…

Soft Condensed Matter · Physics 2013-07-02 Hayato Shiba , Hiroshi Noguchi , Gerhard Gompper

We study the morphology of a fluid membrane in spherical confinement. When the area of the membrane is slightly larger than the area of the outer container, a single axisymmetric invagination is observed. For higher area, self-contact…

Biological Physics · Physics 2012-03-26 Osman Kahraman , Norbert Stoop , Martin Michael Mueller

We revisit the light or heat-induced changes in topography of initially flat sheets of solid that elongate or contract along patterned, in-plane director fields. For radial or azimuthal directors, negative Gaussian curvature is generated --…

Soft Condensed Matter · Physics 2015-06-24 Carl D. Modes , Mark Warner

The effect of rigid inclusions on the phase behavior of a film containing a mixture of lipid molecules is investigated. In the proposed model, the inclusion-induced deformation of the film, and the resulting energy cost are strongly…

Soft Condensed Matter · Physics 2009-10-31 P. Sens , S. Safran

We study a dynamical curvature instability caused by a local chemical modification of a phospholipid membrane. In our experiments, a basic solution is microinjected close to a giant unilamellar vesicle, which induces a local chemical…

Soft Condensed Matter · Physics 2015-03-19 Anne-Florence Bitbol , Jean-Baptiste Fournier , Miglena I. Angelova , Nicolas Puff

We present a general and systematic theory of non-equilibrium dynamics of multi-component fluid membranes, in general, and membranes containing transmembrane proteins, in particular. Developed based on a minimal number of principles of…

Soft Condensed Matter · Physics 2009-11-10 Michael A. Lomholt , Per L. Hansen , Ling Miao
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