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We study a population model of fixed size undergoing strong selection where individuals accumulate beneficial mutations, namely the Moran model with selection. In a specific setting with strong selection, Schweinsberg showed that the…

Probability · Mathematics 2021-03-31 François Gaston Ged

We study the evolution of the population genealogy in the classic neutral Moran Model of finite size and in discrete time. The stochastic transformations that shape a Moran population can be realized directly on its genealogy and give rise…

Populations and Evolution · Quantitative Biology 2019-02-08 Johannes Wirtz , Thomas Wiehe

We study the evolution of a population in a two-locus genotype space, in which the negative effects of two single mutations are overcompensated in a high fitness double mutant. We discuss how the interplay of finite population size, $N$,…

Populations and Evolution · Quantitative Biology 2011-02-23 Alexander Altland , Andrej Fischer , Joachim Krug , Ivan G. Szendro

We study the interplay of population growth and evolutionary dynamics using a stochastic model based on birth and death events. In contrast to the common assumption of an independent population size, evolution can be strongly affected by…

Populations and Evolution · Quantitative Biology 2012-06-05 Jonas Cremer , Anna Melbinger , Erwin Frey

Predicting evolution of expanding populations is critical to control biological threats such as invasive species and cancer metastasis. Expansion is primarily driven by reproduction and dispersal, but nature abounds with examples of…

Populations and Evolution · Quantitative Biology 2019-04-26 Maxime Deforet , Carlos Carmona-Fontaine , Kirill S. Korolev , Joao B. Xavier

We study the fixation probability of a mutant type when introduced into a resident population. As opposed to the usual assumption of constant pop- ulation size, we allow for stochastically varying population sizes. This is implemented by a…

Populations and Evolution · Quantitative Biology 2018-06-08 Peter Czuppon , Arne Traulsen

We study a model for the evolutionarily stable strategy (ESS) used by biological populations for choosing the time of life-history events, such as migration and breeding. In our model we accounted for both intra-species competition (early…

Classical Analysis and ODEs · Mathematics 2015-05-04 Daniela Bertacchi , Fabio Zucca , Roberto Ambrosini

The presence of phenomena analogous to phase transition in Statistical Mechanics, has been suggested in the evolution of a polygenic trait under stabilizing selection, mutation and genetic drift. By using numerical simulations of a model…

Populations and Evolution · Quantitative Biology 2017-02-13 Annalisa Fierro , Sergio Cocozza , Antonella Monticelli , Giovanni Scala , Gennaro Miele

The contribution to an organism's phenotype from one genetic locus may depend upon the status of other loci. Such epistatic interactions among loci are now recognized as fundamental to shaping the process of adaptation in evolving…

Populations and Evolution · Quantitative Biology 2012-12-18 Jeremy A. Draghi , Joshua B. Plotkin

Cellular differentiation and evolution are stochastic processes that can involve multiple types (or states) of particles moving on a complex, high-dimensional state-space or "fitness" landscape. Cells of each specific type can thus be…

Populations and Evolution · Quantitative Biology 2014-11-17 Tom Chou , Yu Wang

A model for the evolution of a finite population in a rugged fitness landscape is introduced and solved. The population is trapped in an evolutionary loop, alternating periods of stasis to periods in which it performs adaptive walks. The…

Disordered Systems and Neural Networks · Physics 2009-10-31 Luca Peliti

This paper presents a stochastic model motivated by the study of a virus-like evolving population with different mutation rates. This is a continuous time birth-death model: the birth processes are mutually-exciting Hawkes processes and the…

Probability · Mathematics 2026-03-10 Rahul Roy , Dharmaraja Selvamuthu , Paola Tardelli

For the voter model, we study the effect of a memory-dependent transition rate. We assume that the transition of a spin into the opposite state decreases with the time it has been in its current state. Counter-intuitively, we find that the…

Disordered Systems and Neural Networks · Physics 2009-11-13 Hans-Ulrich Stark , Claudio J. Tessone , Frank Schweitzer

We study a stochastic spatial model of biological competition in which two species have the same birth and death rates, but different diffusion constants. In the absence of this difference, the model can be considered as an off-lattice…

Populations and Evolution · Quantitative Biology 2015-06-16 Simone Pigolotti , Roberto Benzi

We are interested in the impact of natural selection in a prey-predator community. We introduce an individual-based model of the community that takes into account both prey and predator phenotypes. Our aim is to understand the phenotypic…

Populations and Evolution · Quantitative Biology 2015-02-19 Manon Costa , Céline Hauzy , Nicolas Loeuille , Sylvie Méléard

Mutation and drift play opposite roles in genetics. While mutation creates diversity, drift can cause gene variants to disappear, especially when they are rare. In the absence of natural selection and migration, the balance between the…

Populations and Evolution · Quantitative Biology 2021-11-29 Gabriella D. Franco , Flavia M. D. Marquitti , Lucas D. Fernandes , Dan Braha , Marcus A. M. de Aguiar

We study a generalized discrete-time multi-type Wright-Fisher population process. The mean-field dynamics of the stochastic process is induced by a general replicator difference equation. We prove several results regarding the asymptotic…

Probability · Mathematics 2019-12-06 Alexander Roitershtein , Reza Rastegar , Robert S. Chapkin , Ivan Ivanov

The aim of this paper is to study the large population limit of a binary branching particle system with Moran type interactions: we introduce a new model where particles evolve, reproduce and die independently and, with a probability that…

Probability · Mathematics 2024-04-12 Alexander M. G. Cox , Emma Horton , Denis Villemonais

The biological theory of adaptive dynamics proposes a description of the long-term evolution of a structured asexual population. It is based on the assumptions of large population, rare mutations and small mutation steps, that lead to a…

Probability · Mathematics 2007-05-23 Nicolas Champagnat , Amaury Lambert

We study a discrete-time stochastic process that can also be interpreted as a model for a viral evolution. A distinguishing feature of our process is power-law tails due to dynamics that resembles preferential attachment models. In the…

Probability · Mathematics 2020-06-17 Iddo Ben-Ari , Carter Bedsole , Grace O'Neil