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In regression and causal inference, controlled subgroup selection aims to identify, with inferential guarantees, a subgroup (defined as a subset of the covariate space) on which the average response or treatment effect is above a given…
Objective: Automatic text summarization tools can help users in the biomedical domain to access information efficiently from a large volume of scientific literature and other sources of text documents. In this paper, we propose a…
Objective: The aim of this study was to build an effective co-reference resolution system tailored for the biomedical domain. Materials and Methods: Experiment materials used in this study is provided by the 2011 i2b2 Natural Language…
Semantic hashing represents documents as compact binary vectors (hash codes) and allows both efficient and effective similarity search in large-scale information retrieval. The state of the art has primarily focused on learning hash codes…
Semantic segmentation is a crucial task in biomedical image processing, which recent breakthroughs in deep learning have allowed to improve. However, deep learning methods in general are not yet widely used in practice since they require…
Many problems within personalized medicine and digital health rely on the analysis of continuous-time functional biomarkers and other complex data structures emerging from high-resolution patient monitoring. In this context, this work…
Information retrieval (IR) for precision medicine (PM) often involves looking for multiple pieces of evidence that characterize a patient case. This typically includes at least the name of a condition and a genetic variation that applies to…
This paper describes the software implementation of genetic algorithm for identifying and selecting most relevant results received during sequentially executed subject search operations. Simulated evolutionary process generates sustainable…
Recent advancements in retrieval-augmented generation (RAG) have significantly enhanced the ability of large language models (LLMs) to perform complex question-answering (QA) tasks. In this paper, we introduce MedBioRAG, a…
In the context of personalized medicine, text mining methods pose an interesting option for identifying disease-gene associations, as they can be used to generate novel links between diseases and genes which may complement knowledge from…
Analysis of multi-source dataset, where data on the same objects are collected from multiple sources, is of rising importance in many fields, most notably in multi-omics biology. A novel framework and algorithms for integrative…
Advanced omics technologies and facilities generate a wealth of valuable data daily; however, the data often lacks the essential metadata required for researchers to find and search them effectively. The lack of metadata poses a significant…
Scientific publications play a vital role in the career of a researcher. However, some articles become more popular than others among the research community and subsequently drive future research directions. One of the indicative signs of…
BIRCH clustering is a widely known approach for clustering, that has influenced much subsequent research and commercial products. The key contribution of BIRCH is the Clustering Feature tree (CF-Tree), which is a compressed representation…
Algorithmic classifications of research publications can be used to study many different aspects of the science system, such as the organization of science into fields, the growth of fields, interdisciplinarity, and emerging topics. How to…
ICU mortality scoring systems attempt to predict patient mortality using predictive models with various clinical predictors. Examples of such systems are APACHE, SAPS and MPM. However, most such scoring systems do not actively look for and…
Automated dermoscopic image analysis has witnessed rapid growth in diagnostic performance. Yet adoption faces resistance, in part, because no evidence is provided to support decisions. In this work, an approach for evidence-based…
Clinical and genomic models are both used to predict breast cancer outcomes, but they are often combined using simple linear rules that do not account for how their risk scores relate, especially at the extremes. Using the METABRIC breast…
We propose CHiLL (Crafting High-Level Latents), an approach for natural-language specification of features for linear models. CHiLL prompts LLMs with expert-crafted queries to generate interpretable features from health records. The…
Tabular data prediction has been employed in medical applications such as patient health risk prediction. However, existing methods usually revolve around the algorithm design while overlooking the significance of data engineering. Medical…