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Cluster analysis has proved to be an invaluable tool for the exploratory and unsupervised analysis of high dimensional datasets. Among methods for clustering, hierarchical approaches have enjoyed substantial popularity in genomics and other…

Methodology · Statistics 2014-11-20 Patrick K. Kimes , Yufeng Liu , D. Neil Hayes , J. S. Marron

In this study, we investigated the application of bio-inspired optimization algorithms, including Genetic Algorithm, Particle Swarm Optimization, and Whale Optimization Algorithm, for feature selection in chronic disease prediction. The…

Neural and Evolutionary Computing · Computer Science 2024-01-12 Abeer Dyoub , Ivan Letteri

The cost of DNA sequencing has dropped exponentially over the past decade, making genomic data accessible to a growing number of scientists. In bioinformatics, localization of short DNA sequences (reads) within large genomic sequences is…

Genomics · Quantitative Biology 2021-06-16 Robin Kobus , André Müller , Daniel Jünger , Christian Hundt , Bertil Schmidt

The Medical Subject Headings (MeSH) thesaurus is a controlled vocabulary widely used in biomedical knowledge systems, particularly for semantic indexing of scientific literature. As the MeSH hierarchy evolves through annual version updates,…

Digital Libraries · Computer Science 2021-07-28 Anastasios Nentidis , Anastasia Krithara , Grigorios Tsoumakas , Georgios Paliouras

The discovery of causal relationships from high-dimensional data is a major open problem in bioinformatics. Machine learning and feature attribution models have shown great promise in this context but lack causal interpretation. Here, we…

Machine Learning · Computer Science 2023-04-26 Payam Dibaeinia , Saurabh Sinha

The clinical notes are usually typed into the system by physicians. They are typically required to be marked by standard medical codes, and each code represents a diagnosis or medical treatment procedure. Annotating these notes is time…

Machine Learning · Computer Science 2023-05-10 Guodong Liu

We present a content-based method for recommending citations in an academic paper draft. We embed a given query document into a vector space, then use its nearest neighbors as candidates, and rerank the candidates using a discriminative…

Computation and Language · Computer Science 2018-02-26 Chandra Bhagavatula , Sergey Feldman , Russell Power , Waleed Ammar

Citation recommendation aims to locate the important papers for scholars to cite. When writing the citing sentences, the authors usually hold different citing intents, which are referred to citation function in citation analysis. Since…

Information Retrieval · Computer Science 2025-01-31 Shutian Ma , Chengzhi Zhang , Heng Zhang , Zheng Gao

Causal relation extraction (CRE) is central to biomedical text mining, but current resources often conflate causal relations with broader associations, restrict annotation to sentence-level examples, or focus mainly on explicit causal cues.…

Computation and Language · Computer Science 2026-05-28 Ifeoluwa Kunle-John , Josiah Paul , Oluwatosin Agbaakin , Peter Aina , Ikenna Odezuligbo , Sydney Anuyah

The identification of disease-gene associations is instrumental in understanding the mechanisms of diseases and developing novel treatments. Besides identifying genes from RNA-Seq datasets, it is often necessary to identify gene clusters…

Genomics · Quantitative Biology 2025-11-14 Jake R. Patock , Rinki Ratnapriya , Arko Barman

Genetic algorithms are a widely used method in chemometrics for extracting variable subsets with high prediction power. Most fitness measures used by these genetic algorithms are based on the ordinary least-squares fit of the resulting…

Computation · Statistics 2017-11-21 David Kepplinger , Peter Filzmoser , Kurt Varmuza

Medical decision-making makes frequent use of algorithms that combine risk equations with rules, providing clear and standardized treatment pathways. Symbolic regression (SR) traditionally limits its search space to continuous function…

The field of scientometrics has shown the power of citation-based clusters for literature analysis, yet this technique has barely been used for information retrieval tasks. This work evaluates the performance of citation based-clusters for…

Digital Libraries · Computer Science 2023-10-06 Juan Pablo Bascur , Suzan Verberne , Nees Jan van Eck , Ludo Waltman

In this paper, we present an accurate and extensible approach for the coreference resolution task. We formulate the problem as a span prediction task, like in machine reading comprehension (MRC): A query is generated for each candidate…

Computation and Language · Computer Science 2020-07-21 Wei Wu , Fei Wang , Arianna Yuan , Fei Wu , Jiwei Li

We lay the foundations of a statistical framework for multi-catalogue cross-correlation and cross-identification based on explicit simplified catalogue models. A proper identification process should rely on both astrometric and photometric…

Instrumentation and Methods for Astrophysics · Physics 2017-01-11 F. -X. Pineau , S. Derriere , C. Motch , F. J. Carrera , F. Genova , L. Michel , B. Mingo , A. Mints , A. Nebot Gómez-Morán , S. R. Rosen , A. Ruiz Camuñas

Medical report generation is one of the most challenging tasks in medical image analysis. Although existing approaches have achieved promising results, they either require a predefined template database in order to retrieve sentences or…

Computation and Language · Computer Science 2021-06-14 Xingyi Yang , Muchao Ye , Quanzeng You , Fenglong Ma

Advances in bio-technology have made available massive amounts of functional, structural and genomic data for many biological sequences. This increased availability of heterogeneous biological data has resulted in biological applications…

Computational Engineering, Finance, and Science · Computer Science 2013-02-26 Srikrishnan Divakaran , Arpit Mithal , Namit Jain

In the genomic era, the identification of gene signatures associated with disease is of significant interest. Such signatures are often used to predict clinical outcomes in new patients and aid clinical decision-making. However, recent…

Methodology · Statistics 2019-03-27 Naim U. Rashid , Quefeng Li , Jen Jen Yeh , Joseph G. Ibrahim

Identifying significant subsets of the genes, gene shaving is an essential and challenging issue for biomedical research for a huge number of genes and the complex nature of biological networks,. Since positive definite kernel based methods…

Machine Learning · Statistics 2018-09-06 Md. Ashad Alam , Mohammad Shahjama , Md. Ferdush Rahman

Medical language processing and deep learning techniques have emerged as critical tools for improving healthcare, particularly in the analysis of medical imaging and medical text data. These multimodal data fusion techniques help to improve…

Computation and Language · Computer Science 2025-04-28 Sayeh Gholipour Picha , Dawood Al Chanti , Alice Caplier
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