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Physarum polycephalum is an acellular slime mould that grows as a highly adaptive network of veins filled with protoplasm. As it forages, Physarum dynamically rearranges its network structure as a response to local stimuli information,…

Fluid Dynamics · Physics 2023-05-23 Rodrigo Almeida , Rui Dilão

We implement Kolmogorov-Uspensky machine on a plasmodium of true slime mold {\em Physarum polycephalum}. We provide experimental findings on realization of the machine instructions, illustrate basic operations, and elements of programming.

Hardware Architecture · Computer Science 2010-11-23 Andrew Adamatzky

The giant single-celled slime mould Physarum polycephalum exhibits complex morphological adaptation and amoeboid movement as it forages for food and may be seen as a minimal example of complex robotic behaviour. Swarm computation has…

Multiagent Systems · Computer Science 2012-12-04 Jeff Jones , Andrew Adamatzky

A sub-excitable BZ medium responds to asymmetric local perturbation by producing travelling localised excitation wave-fragments, distant relatives of dissipative solitons. The size and life span of an excitation wave-fragment depend on the…

Emerging Technologies · Computer Science 2015-10-28 Andrew Adamatzky

Plasmonic logic circuits combine ultrafast operation with nanoscale integration, making them a strong candidate for next-generation optical computing. Realizing this potential, however, requires overcoming practical challenges such as bulky…

Optics · Physics 2025-10-07 Komal Gupta , Anand Hegde , Chen-Bin Huang

True slime mould Physarum polycephalum approximates a range of complex computations via growth and adaptation of its proto- plasmic transport network, stimulating a large body of recent research into how such a simple organism can perform…

Emerging Technologies · Computer Science 2015-03-12 Jeff Jones , Andrew Adamatzky

The slime mould Physarum polycephalum displays adaptive transport dynamics and network formation that have inspired its use as a model of biological computation. We develop a Lagrangian formulation of Physarum's adaptive dynamics on…

Neurons and Cognition · Quantitative Biology 2025-11-12 Ricard Solé , Jordi Pla-Mauri

Collective movement occurs in living systems where the simple movements of individual members of a pop- ulation are combined to generate movement of the collective as a whole, displaying complex dynamics which cannot be found in the…

Emerging Technologies · Computer Science 2015-11-25 Jeff Jones

The giant single-celled amoeboid organism Physarum polycephalum constructs minimising transport networks but can also approximate the Voronoi diagram using two different mechanisms. In the first method Voronoi bisectors are rep- resented by…

Emerging Technologies · Computer Science 2015-03-25 Jeff Jones , Andrew Adamatzky

Physarum polycephalum is a single-celled, multi-nucleated slime mold whose body constitutes a network of veins. As it explores its environment, it adapts and optimizes its network to external stimuli. It has been shown to exhibit complex…

Fluid Dynamics · Physics 2023-09-20 Ana Filipa Valente

Acellular slime mould Physarum polycephalum is a popular now user-friendly living substrate for designing of future and emergent sensing and computing devices. P. polycephalum exhibits regular patterns of oscillations of its surface…

Emerging Technologies · Computer Science 2013-12-17 Andrew Adamatzky

The true slime mould Physarum polycephalum is a recent well studied example of how complex transport networks emerge from simple auto-catalytic and self- organising local interactions, adapting structure and function against changing…

Emerging Technologies · Computer Science 2015-03-29 Jeff Jones

In the realm of biological flow networks, the ability to dynamically adjust to varying demands is paramount. Drawing inspiration from the remarkable adaptability of Physarum polycephalum, we present a novel physical mechanism tailored to…

Soft Condensed Matter · Physics 2023-10-05 Vidyesh Rao Anisetti , Ananth Kandala , J. M. Schwarz

This paper proposes the use of Eukaryotic cells, namely astrocytes, to develop logic gates. The logic gates are achieved by manipulating the threshold of Ca$^{2+}$ ion flows between the cells, based on the input signals. Through wet-lab…

Mycelium networks are promising substrates for designing unconventional computing devices providing rich topologies and geometries where signals propagate and interact. Fulfilling our long-term objectives of prototyping electrical analog…

Emerging Technologies · Computer Science 2021-07-02 Alexander E. Beasley , Phil Ayres , Martin Tegelaar , Michail-Antisthenis Tsompanas , Andrew Adamatzky

Optimization of fluid transport in the slime mold Physarum polycephalum has been the subject of several modeling efforts in recent literature. Existing models assume that the tube adaptation mechanism in P. polycephalum's tubular network is…

Tissues and Organs · Quantitative Biology 2019-07-01 Vincenzo Bonifaci

Multi-nucleated cells exist in all domains of life, ranging from animals, plants and fungi to single-celled organisms such as the slime mold Physarum polycephalum. The large cell size, in the case of Physarum reaching centimeters and more,…

Biological Physics · Physics 2026-05-12 Johnny Tong , Kaspar Wachinger , Fabian K. Henn , Nico Schramma , Siyu Chen , Karen Alim

Living substrates are capable for nontrivial mappings of electrical signals due to the substrate nonlinear electrical characteristics. This property can be used to realise Boolean functions. Input logical values are represented by amplitude…

Emerging Technologies · Computer Science 2021-08-12 Nic Roberts , Andrew Adamatzky

A fungal colony maintains its integrity via flow of cytoplasm along mycelium network. This flow, together with possible coordination of mycelium tips propagation, is controlled by calcium waves and associated waves of electrical potential…

Emerging Technologies · Computer Science 2020-02-25 Andrew Adamatzky , Martin Tegelaar , Han A. B. Wosten , Anna L. Powell , Alexander E. Beasley , Richard Mayne

Memristors have been suggested as a novel route to neuromorphic computing based on the similarity between them and neurons (specifically synapses and ion pumps). The d.c. action of the memristor is a current spike which imparts a short-term…

Emerging Technologies · Computer Science 2015-10-21 Ella Gale