Related papers: Pooling Design and Bias Correction in DNA Library …
In binary classification, there are situations where negative (N) data are too diverse to be fully labeled and we often resort to positive-unlabeled (PU) learning in these scenarios. However, collecting a non-representative N set that…
Detection of rare variants by resequencing is important for the identification of individuals carrying disease variants. Rapid sequencing by new technologies enables low-cost resequencing of target regions, although it is still prohibitive…
In cancer research, clustering techniques are widely used for exploratory analyses and dimensionality reduction, playing a critical role in the identification of novel cancer subtypes, often with direct implications for patient management.…
The compact genetic algorithm is an Estimation of Distribution Algorithm for binary optimisation problems. Unlike the standard Genetic Algorithm, no cross-over or mutation is involved. Instead, the compact Genetic Algorithm uses a virtual…
We consider the problem of non-adaptive group testing of $N$ items out of which $K$ or less items are known to be defective. We propose a testing scheme based on left-and-right-regular sparse-graph codes and a simple iterative decoder. We…
We study the problem of clustering a set of items from binary user feedback. Such a problem arises in crowdsourcing platforms solving large-scale labeling tasks with minimal effort put on the users. For example, in some of the recent…
Consider a very large (infinite) population of items, where each item independent from the others is defective with probability p, or good with probability q=1-p. The goal is to identify N good items as quickly as possible. The following…
Approximate Bayesian computation (ABC) is an approach for sampling from an approximate posterior distribution in the presence of a computationally intractable likelihood function. A common implementation is based on simulating model,…
This paper introduces a new Python package specifically designed to address calibration of probabilistic classifiers under dataset shift. The method is demonstrated in binary and multi-class settings and its effectiveness is measured…
Screening traditionally refers to the problem of detecting active inputs in the computer model. In this paper, we develop methodology that applies to screening, but the main focus is on detecting active inputs not in the computer model…
Learning group representation is a commonly concerned issue in tasks where the basic unit is a group, set, or sequence. Previously, the research community tries to tackle it by aggregating the elements in a group based on an indicator…
Group testing algorithms are very useful tools for DNA library screening. Building on recent work by Levenshtein (2003) and Tonchev (2008), we construct in this paper new infinite classes of combinatorial structures, the existence of which…
Genome-wide association analysis has generated much discussion about how to preserve power to detect signals despite the detrimental effect of multiple testing on power. We develop a weighted multiple testing procedure that facilitates the…
Genome wide comparisons between enteric bacteria yield large sets of conserved putative regulatory sites on a gene by gene basis that need to be clustered into regulons. Using the assumption that regulatory sites can be represented as…
In group testing, the goal is to identify a subset of defective items within a larger set of items based on tests whose outcomes indicate whether any defective item is present. This problem is relevant in areas such as medical testing, data…
As one of the most effective self-supervised representation learning methods, contrastive learning (CL) relies on multiple negative pairs to contrast against each positive pair. In the standard practice of contrastive learning, data…
Bayesian clustering methods have the widely touted advantage of providing a probabilistic characterization of uncertainty in clustering through the posterior distribution. An amazing variety of priors and likelihoods have been proposed for…
A code clone is a pair of code fragments, within or between software systems that are similar. Since code clones often negatively impact the maintainability of a software system, several code clone detection techniques and tools have been…
This paper considers the problem of Quantitative Group Testing (QGT) where there are some defective items among a large population of $N$ items. We consider the scenario in which each item is defective with probability $K/N$, independently…
Recent advances in deep learning have made the use of large, deep neural networks with tens of millions of parameters. The sheer size of these networks imposes a challenging computational burden during inference. Existing work focuses…