English
Related papers

Related papers: Pooling Design and Bias Correction in DNA Library …

200 papers

The group testing problem consists of determining a sparse subset of defective items from within a larger set of items via a series of tests, where each test outcome indicates whether at least one defective item is included in the test. We…

Information Theory · Computer Science 2026-04-24 Daniel McMorrow , Jonathan Scarlett

Population-wide screening is a powerful tool for controlling infectious diseases. Group testing enables such screening despite limited resources. Viral concentration of pooled samples are often positively correlated, either because…

Applications · Statistics 2025-04-01 Jiayue Wan , Yujia Zhang , Peter I. Frazier

For large classes of group testing problems, we derive lower bounds for the probability that all significant items are uniquely identified using specially constructed random designs. These bounds allow us to optimize parameters of the…

Statistics Theory · Mathematics 2022-02-17 Jack Noonan , Anatoly Zhigljavsky

The study in group testing aims to develop strategies to identify a small set of defective items among a large population using a few pooled tests. The established techniques have been highly beneficial in a broad spectrum of applications…

Information Theory · Computer Science 2025-01-23 Venkata Gandikota , Nikita Polyanskii , Haodong Yang

Group testing enables the identification of a small subset of defective items within a larger population by performing tests on pools of items rather than on each item individually. Over the years, it has not only attracted attention from…

Information Theory · Computer Science 2026-01-13 Manuel Franco-Vivo

In this paper we describe a new technique for the comparison of populations of DNA strands. Comparison is vital to the study of ecological systems, at both the micro and macro scales. Existing methods make use of DNA sequencing and cloning,…

Biomolecules · Quantitative Biology 2008-07-02 Dennis Shasha , Martyn Amos

This paper describes a classifier pool generation method guided by the diversity estimated on the data complexity and classifier decisions. First, the behavior of complexity measures is assessed by considering several subsamples of the…

Machine Learning · Computer Science 2020-11-04 Marcos Monteiro , Alceu S. Britto , Jean P. Barddal , Luiz S. Oliveira , Robert Sabourin

Scientists often must simultaneously localize and discover signals. For instance, in genetic fine-mapping, high correlations between nearby genetic variants make it hard to identify the exact locations of causal variants. So the statistical…

Methodology · Statistics 2023-01-31 Asher Spector , Lucas Janson

Learning contrastive representations from pairwise comparisons has achieved remarkable success in various fields, such as natural language processing, computer vision, and information retrieval. Collaborative filtering algorithms based on…

Information Retrieval · Computer Science 2023-08-01 Bin Liu , Qin Luo , Bang Wang

In the classical non-adaptive group testing setup, pools of items are tested together, and the main goal of a recovery algorithm is to identify the "complete defective set" given the outcomes of different group tests. In contrast, the main…

Information Theory · Computer Science 2016-03-01 Abhay Sharma , Chandra R. Murthy

The basic goal in combinatorial group testing is to identify a set of up to $d$ defective items within a large population of size $n \gg d$ using a pooling strategy. Namely, the items can be grouped together in pools, and a single…

Discrete Mathematics · Computer Science 2013-01-21 Mahdi Cheraghchi

We present a novel subset scan method to detect if a probabilistic binary classifier has statistically significant bias -- over or under predicting the risk -- for some subgroup, and identify the characteristics of this subgroup. This form…

Machine Learning · Statistics 2017-07-05 Zhe Zhang , Daniel B. Neill

Clustering is a crucial task in various domains of knowledge, including medicine, epidemiology, genomics, environmental science, economics, and visual sciences, among others. Methodologies for inferring the number of clusters have often…

Methodology · Statistics 2025-05-26 Clara Grazian

Group-testing refers to the problem of identifying (with high probability) a (small) subset of $D$ defectives from a (large) set of $N$ items via a "small" number of "pooled" tests. For ease of presentation in this work we focus on the…

Information Theory · Computer Science 2013-07-11 Sheng Cai , Mohammad Jahangoshahi , Mayank Bakshi , Sidharth Jaggi

In many scientific settings there is a need for adaptive experimental design to guide the process of identifying regions of the search space that contain as many true positives as possible subject to a low rate of false discoveries (i.e.…

Machine Learning · Statistics 2020-08-18 Lalit Jain , Kevin Jamieson

We consider a new group testing model wherein each item is a binary random variable defined by an a priori probability of being defective. We assume that each probability is small and that items are independent, but not necessarily…

Information Theory · Computer Science 2018-07-24 Tongxin Li , Chun Lam Chan , Wenhao Huang , Tarik Kaced , Sidharth Jaggi

Data pooling offers various advantages, such as increasing the sample size, improving generalization, reducing sampling bias, and addressing data sparsity and quality, but it is not straightforward and may even be counterproductive.…

Computer Vision and Pattern Recognition · Computer Science 2024-05-09 Stefan Becker , Jens Bayer , Ronny Hug , Wolfgang Hübner , Michael Arens

In probabilistic nonadaptive group testing (PGT), we aim to characterize the number of pooled tests necessary to identify a random $k$-sparse vector of defectives with high probability. Recent work has shown that $n$ tests are necessary…

Information Theory · Computer Science 2021-06-15 Larkin Flodin , Arya Mazumdar

In collaborative forecast projects, the combining of multiple probabilistic forecasts into an ensemble is standard practice, with linear pooling being a common combination method. The weighting scheme of a linear pool should be tailored to…

Methodology · Statistics 2025-09-05 Spencer Wadsworth , Jarad Niemi

In group testing, simple binary-output tests are designed to identify a small number $t$ of defective items that are present in a large population of $N$ items. Each test takes as input a group of items and produces a binary output…

Information Theory · Computer Science 2017-04-11 Alexander Barg , Arya Mazumdar