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A stochastic walker model is proposed to describe the chemotactic guidance of growth cones, i.e. the tips of developing neurites. The model accounts for the influence of both attractive and repulsive chemical cues, which are emitted by the…

Analysis of PDEs · Mathematics 2025-11-04 Noah Geltner , Ansgar Jüngel

Correct prediction of particle transport by surface waves is crucial in many practical applications such as search and rescue or salvage operations and pollution tracking and clean-up efforts. Recent results have indicated transport by…

Fluid Dynamics · Physics 2023-01-26 D. Eeltink , R. Calvert , J. E. Swagemakers , Qian Xiao , T. S. van den Bremer

The propagation of signalling molecules within cellular networks is affected by network topology, but also by the spatial arrangement of cells in the networks. Understanding the collective reaction--diffusion behaviour in space of signals…

Disordered Systems and Neural Networks · Physics 2025-01-09 Adel Mehrpooya , Vivien J. Challis , Pascal R. Buenzli

Stochastic models of biochemical reaction networks are widely used to capture intrinsic noise in cellular systems. The typical formulation of these models are based on Markov processes for which there is extensive research on efficient…

Molecular Networks · Quantitative Biology 2025-12-03 Thomas P. Steele , David J. Warne

We present some computer simulations run on a stochastic CA (cellular automaton). The CA simulates a gas of particles which are in a channel, the interval $[1,L]$ in $\mathbb Z$, but also in "reservoirs" $\mathcal R_1$ and $\mathcal R_2$.…

Statistical Mechanics · Physics 2017-04-26 Matteo Colangeli , Anna De Masi , Errico Presutti

We have developed a coarse-grained formulation for modeling the dynamic behavior of cells quantitatively, based on stochasticity and heterogeneity, rather than on biochemical reactions. We treat each reaction as a continuous-time stochastic…

Molecular Networks · Quantitative Biology 2015-05-28 Shunsuke Teraguchi , Yutaro Kumagai , Alexis Vandenbon , Shizuo Akira , Daron M Standley

In many biological systems localized mechanical information is transmitted by mechanically neutral chemical signals. Typical examples include contraction waves in acto-myosin cortex at cellular scale and peristaltic waves at tissue level.…

Soft Condensed Matter · Physics 2025-11-25 Lev Truskinovsky , Giuseppe Zurlo

It is shown, by means of numerical simulations, that intercellular spiral waves of calcium can be initiated in a network of coupled cells as a result of a de-synchronization between Ca2+ oscillations in two domains. No artificial…

Molecular Networks · Quantitative Biology 2010-10-14 Wilfred D. Kepseu , Paul Woafo , H. Sakaguchi

Precipitation/dissolution reactions coupled with solute transport are modelled as a cellular automaton in which solute molecules perform a random walk on a regular lattice and react according to a local probabilistic rule. Stationary solid…

comp-gas · Physics 2009-10-28 T. Karapiperis

We develop a coarse grained (CG) approach for efficiently simulating calcium dynamics in the endoplasmic reticulum membrane based on a fine stochastic lattice gas model. By grouping neighboring microscopic sites together into CG cells and…

Chemical Physics · Physics 2015-06-15 Chuansheng Shen , Hanshuang Chen

In Bhattacharya et al. (Science Advances, 2020), a set of chemical reactions involved in the dynamics of actin waves in cells was studied. Both at the microscopic level, where the individual chemical reactions are directly modelled using…

Analysis of PDEs · Mathematics 2023-02-01 Christian Hamster , Peter van Heijster

The instability and nonlinear evolution of directional ocean waves is investigated numerically by means of simulations of the governing kinetic equation for narrow-band surface waves. Our simulation results reveal the onset of the…

Fluid Dynamics · Physics 2015-05-14 Bengt Eliasson , Padma K. Shukla

We develop a general theory dealing with stochastic models for dynamical systems that are governed by various nonlinear, ordinary or partial differential, equations. In particular, we address the problem how flows in the random medium…

chao-dyn · Physics 2009-10-31 Piotr Garbaczewski

A connection is established between discrete stochastic model describing microscopic motion of fluctuating cells, and macroscopic equations describing dynamics of cellular density. Cells move towards chemical gradient (process called…

Biological Physics · Physics 2010-05-18 Pavel M. Lushnikov , Nan Chen , Mark Alber

Cell migration is a fundamental process involved in physiological phenomena such as the immune response and morphogenesis, but also in pathological processes, such as the development of tumor metastasis. These functions are effectively…

Cell Behavior · Quantitative Biology 2018-12-26 Christèle Etchegaray , Nicolas Meunier

Intracellular calcium is regulated in part by the release of Ca$^{2+}$ ions from the endoplasmic reticulum via inositol-4,5-triphosphate receptor (IP$_3$R) channels (among other possibilities such as RyR and L-type calcium channels). The…

Subcellular Processes · Quantitative Biology 2016-09-14 Ulrich Dobramysl , Sten Rüdiger , Radek Erban

The computational paradigm represented by Cellular Neural/nonlinear Networks (CNN) and the CNN Universal Machine (CNN-UM) as a Cellular Wave Computer, gives new perspectives for computational physics. Many numerical problems and simulations…

Computational Physics · Physics 2009-11-11 M. Ercsey-Ravasz , T. Roska , Z. Néda

We study nonequilibrium quantum dynamics of spin chains by employing principal component analysis (PCA) on data sets of wave function snapshots and examine how information propagates within these data sets. The quantities we employ are…

Disordered Systems and Neural Networks · Physics 2025-08-28 Devendra Singh Bhakuni , Roberto Verdel , Cristiano Muzzi , Riccardo Andreoni , Monika Aidelsburger , Marcello Dalmonte

We propose a computational method to simulate anomalous self-diffusion in a simple liquid. The method is based on a molecular dynamics simulation on which we impose the following two conditions: firstly, the inter-particle interaction is…

Statistical Mechanics · Physics 2010-04-07 Simon Standaert , Jan Ryckebusch , Lesley De Cruz

In this paper, a general model of wireless channels is established based on the physics of wave propagation. Then the problems of inverse scattering and channel prediction are formulated as nonlinear filtering problems. The solutions to the…

Data Analysis, Statistics and Probability · Physics 2015-06-26 Haiqing Wei