It is shown, by means of numerical simulations, that intercellular spiral waves of calcium can be initiated in a network of coupled cells as a result of a de-synchronization between Ca2+ oscillations in two domains. No artificial heterogeneities need to be imposed to the system for spontaneous formation of spiral waves. The de-synchronization occurs near the interface of the stimulated region (which acts as a pacemaker) and propagates over the entire network. We also find the outcome of the collision of two spiral waves.
@article{arxiv.1010.2508,
title = {Intercellular spiral waves of calcium in a two dimensional network of cells},
author = {Wilfred D. Kepseu and Paul Woafo and H. Sakaguchi},
journal= {arXiv preprint arXiv:1010.2508},
year = {2010}
}