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The identification and modeling of time-varying systems is a fundamental challenge in signal processing and system identification. To address this challenge, we propose a class of time-varying state-space model (SSM) based neural networks…

Machine Learning · Computer Science 2026-05-18 Sanja Karilanova , Subhrakanti Dey , Ayça Özçelikkale

Music, being a multifaceted stimulus evolving at multiple timescales, modulates brain function in a manifold way that encompasses not only the distinct stages of auditory perception but also higher cognitive processes like memory and…

Neurons and Cognition · Quantitative Biology 2018-02-06 Dimitrios A. Adamos , Nikolaos Laskaris , Sifis Micheloyannis

Cells can utilize chemical communication to exchange information and coordinate their behavior in the presence of noise. Communication can reduce noise to shape a collective response, or amplify noise to generate distinct phenotypic…

Molecular Networks · Quantitative Biology 2019-09-24 David T. Gonzales , T-Y Dora Tang , Christoph Zechner

We study two delay-coupled FitzHugh-Nagumo systems, introducing a mismatch between the delay times, as the simplest representation of interacting neurons. We demonstrate that the presence of delays can cause periodic oscillations which…

Adaptation and Self-Organizing Systems · Physics 2009-11-12 Anastasiia Panchuk , Markus Dahlem , Eckehard Schöll

Patients at high risk for sudden death often exhibit complex heart rhythms in which abnormal heartbeats are interspersed with normal heartbeats. We analyze such a complex rhythm in a single patient over a 12-hour period and show that the…

Neurons in the central nervous system are affected by complex and noisy signals due to fluctuations in their cellular environment and in the inputs they receive from many other cells 1,2. Such noise usually increases the probability that a…

Neurons and Cognition · Quantitative Biology 2008-05-06 Boris S. Gutkin , Juergen Jost , Henry C. Tuckwell

Cell systems consist of a huge number of various molecules that display specific patterns of interactions, which have a determining influence on the cell's functioning. In general, such complexity is seen to increase with the complexity of…

Biomolecules · Quantitative Biology 2014-03-14 Marianne Rooman , Jaroslav Albert , Mitia Duerinckx

We use particle dynamics simulations to probe the correlations between noise and dynamics in a variety of disordered systems, including superconducting vortices, 2D electron liquid crystals, colloids, domain walls, and granular media. The…

Superconductivity · Physics 2009-11-10 C. J. Olson Reichhardt , C. Reichhardt

Spike generation in neurons produces a temporal point process, whose statistics is governed by intrinsic phenomena and the external incoming inputs to be coded. In particular, spike-evoked adaptation currents support a slow temporal process…

Neurons and Cognition · Quantitative Biology 2016-10-31 Eugenio Urdapilleta

Several studies highlighted the relevance of extrinsic noise in shaping cell decision making and differentiation in molecular networks. Experimental evidences of phenotypic differentiation are given by the presence of bimodal distributions…

Molecular Networks · Quantitative Biology 2017-04-19 Marco Del Giudice , Stefano Bo , Silvia Grigolon , Carla Bosia

Stochastic transitions between discrete microscopic states play an important role in many physical and biological systems. Often, these transitions lead to fluctuations on a macroscopic scale. A classic example from neuroscience is the…

Statistical Mechanics · Physics 2024-02-20 Lukas Ramlow , Benjamin Lindner

Modern neural recording techniques allow neuroscientists to obtain spiking activity of multiple neurons from different brain regions over long time periods, which requires new statistical methods to be developed for understanding structure…

Applications · Statistics 2023-12-29 Ganchao Wei

Differential equation-based physiological models of sleep-wake networks describe sleep-wake regulation by simulating the activity of wake- and sleep-promoting neuronal populations and the modulation of these populations by homeostatic and…

Dynamical Systems · Mathematics 2021-11-16 Christina Athanasouli , Sofia H. Piltz , Cecilia Diniz Behn , Victoria Booth

We study a system of dynamical units, each of which shows excitable or oscillatory behavior, depending on the choice of parameters. When we couple these units with repressive bonds, we can control the duration of collective oscillations for…

Molecular Networks · Quantitative Biology 2014-02-06 Darka Labavic , Hildegard Meyer-Ortmanns

The Notch-Delta signaling pathway mediates cell differentiation implicated in many regulatory processes including spatiotemporal patterning in tissues by promoting alternate cell fates between neighboring cells. At the multicellular level,…

Cell Behavior · Quantitative Biology 2022-10-12 Madeline Galbraith , Federico Bocci , José N. Onuchic

Models of solar-like oscillators yield acoustic modes at different frequencies than would be seen in actual stars possessing identical interior structure, due to modelling error near the surface. This asteroseismic "surface term" must be…

Solar and Stellar Astrophysics · Physics 2021-11-24 J. M. Joel Ong , Sarbani Basu , Mikkel N. Lund , Allyson Bieryla , Lucas S. Viani , David W. Latham

In this chapter we review phenomenological models of seizure like activity. We discuss dynamical mechanisms for seizure onset and offset, preictal spikes, spike and wave complexes and status epilepticus, highlighting the role played by the…

Neurons and Cognition · Quantitative Biology 2020-07-07 Maria Luisa Saggio , Viktor Jirsa

We study the interplay between diversity and noise in a 3D network of FitzHugh-Nagumo elements, with topology and dimensions chosen to model a pancreatic beta-cell cluster, as an example of an excitable cell network. Our results show that…

Biological Physics · Physics 2022-03-30 Stefano Scialla , Marco Patriarca , Els Heinsalu

The time domain stability of microwave spin torque oscillators (STOs) has been investigated by systematic micromagnetic simulations. A model based on internal spin wave reflection at grain boundaries with reduced exchange coupling was…

Mesoscale and Nanoscale Physics · Physics 2019-09-19 B. Gunnar Malm , Anders Eklund , Mykola Dvornik

Noise is usually regarded as adversarial to extract the effective dynamics from time series, such that the conventional data-driven approaches usually aim at learning the dynamics by mitigating the noisy effect. However, noise can have a…

Adaptation and Self-Organizing Systems · Physics 2023-09-12 Zequn Lin , Zhaofan Lu , Zengru Di , Ying Tang
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