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We study the stochastic FitzHugh-Nagumo equations, modelling the dynamics of neuronal action potentials, in parameter regimes characterised by mixed-mode oscillations. The interspike time interval is related to the random number of…

Probability · Mathematics 2012-07-10 Nils Berglund , Damien Landon

This work continues the analysis of complex dynamics in a class of bidimensional nonlinear hybrid dynamical systems with resets modeling neuronal voltage dynamics with adaptation and spike emission. We show that these models can generically…

Dynamical Systems · Mathematics 2017-01-05 Jonathan E. Rubin , Justyna Signerska-Rynkowska , Jonathan Touboul , Alexandre Vidal

Bursting oscillations are commonly seen as a mechanism for information coding in neuroscience and have also been observed in many physical, biochemical, and chemical systems. This study focuses on the computational investigation of…

Dynamical Systems · Mathematics 2021-10-15 Na Yu , Xuan Xia , Juan Liyau

We analyze a piecewise-linear FitzHugh-Nagumo model. The system exhibits a canard near which both small amplitude and large amplitude periodic orbits exist. The addition of small noise induces mixed-mode oscillations (MMOs) in the vicinity…

Dynamical Systems · Mathematics 2015-05-20 David J. W. Simpson , Rachel Kuske

In this paper, we focus on the emergence of diverse neuronal oscillations arising in a mixed population of neurons with different excitability properties. These properties produce mixed mode oscillations (MMOs) characterized by the…

Adaptation and Self-Organizing Systems · Physics 2020-05-07 Subrata Ghosh , Argha Mondal , Peng Ji , Arindam Mishra , Syamal Kumar Dana , Chris G. Antonopoulos , Chittaranjan Hens

Mixed mode oscillations (MMOs) are complex oscillatory behaviors of multiple-timescale dynamical systems in which there is an alternation of large-amplitude and small-amplitude oscillations. It is well known that MMOs in two-timescale…

Dynamical Systems · Mathematics 2024-03-01 Ngoc Anh Phan , Yangyang Wang

Self-sustained subthreshold oscillations in a discrete-time model of neuronal behavior are considered. We discuss bifurcation scenarios explaining the birth of these oscillations and their transformation into tonic spikes. Specific features…

Cell Behavior · Quantitative Biology 2009-11-10 Andrey L. Shilnikov , Nikolai F. Rulkov

We have analyzed the interplay between noise and periodic modulations in a mean field model of a neural excitable medium. To this purpose, we have considered two types of modulations; namely, variations of the resistance and oscillations of…

Statistical Mechanics · Physics 2016-08-15 J. M. G. Vilar , R. V. Solé , J. M. Rubí

We study the dynamics of a low-dimensional system of coupled model neurons as a step towards understanding the vastly complex network of neurons in the brain. We analyze the bifurcation structure of a system of two model neurons with…

Dynamical Systems · Mathematics 2019-03-27 Elizabeth N. Davison , Zahra Aminzare , Biswadip Dey , Naomi Ehrich Leonard

We present recent results on noise-induced transitions in a nonlinear oscillator with randomly modulated frequency. The presence of stochastic perturbations drastically alters the dynamical behaviour of the oscillator: noise can wash out a…

Chaotic Dynamics · Physics 2009-11-13 Sebastien Aumaitre , Francois Petrelis , Kirone Mallick

In sensory neurons the presence of noise can facilitate the detection of weak information-carrying signals, which are encoded and transmitted via correlated sequences of spikes. Here we investigate relative temporal order in spike sequences…

Neurons and Cognition · Quantitative Biology 2016-10-12 Jose A. Reinoso , M. C. Torrent , Cristina Masoller

Mixed-mode oscillations (MMOs) are complex oscillatory patterns in which large-amplitude relaxation oscillations (LAOs) alternate with small-amplitude oscillations (SAOs). MMOs are found in singularly perturbed systems of ordinary…

Dynamical Systems · Mathematics 2021-03-10 Yiorgos Patsios , Renato Huzak , Nikola Popovic , Peter De Maesschalck

We analyze the effect of weak-noise-induced transitions on the dynamics of the FitzHugh-Nagumo neuron model in a bistable state consisting of a stable fixed point and a stable unforced limit cycle. Bifurcation and slow-fast analysis give…

Dynamical Systems · Mathematics 2017-06-02 Marius E. Yamakou , Jürgen Jost

Neurons in the nervous system are submitted to distinct sources of noise, such as ionic-channel and synaptic noise, which introduces variability in their responses to repeated presentations of identical stimuli. This motivates the use of…

Alternating patterns of small and large amplitude oscillations occur in a wide variety of physical, chemical, biological and engineering systems. These mixed-mode oscillations (MMOs) are often found in systems with multiple time scales.…

Dynamical Systems · Mathematics 2014-06-24 Christian Kuehn

The effect of stochasticity, in the form of Gaussian white noise, in a predator-prey model with two distinct time-scales is presented. A supercritical singular Hopf bifurcation yields a Type II excitability in the deterministic model. We…

Dynamical Systems · Mathematics 2017-07-20 Susmita Sadhu

We analyze a class of chemical reaction networks under mass-action kinetics and involving multiple time-scales, whose deterministic and stochastic models display qualitative differences. The networks are inspired by gene-regulatory…

Molecular Networks · Quantitative Biology 2018-01-30 Tomislav Plesa , Radek Erban , Hans G. Othmer

We propose theoretical methods to infer coupling strength and noise intensity simultaneously through an observation of spike timing in two well-synchronized noisy oscillators. A phase oscillator model is applied to derive formulae relating…

Biological Physics · Physics 2021-06-25 Fumito Mori , Hiroshi Kori

We find that sensory noise delivered together with a weak periodic signal not only enhances nonlinear response of neuronal networks, but also improves the synchronization of the response to the signal. We reveal this phenomenon in neuronal…

Neurons and Cognition · Quantitative Biology 2015-08-25 M. A. Lopes , K. -E. Lee , A. V. Goltsev , J. F. F. Mendes

We investigate feedback control of the cooperative dynamics of two coupled neural oscillators that is induced merely by external noise. The interacting neurons are modelled as FitzHugh-Nagumo systems with parameter values at which no…

Chaotic Dynamics · Physics 2009-11-11 B. Hauschildt , N. B. Janson , A. Balanov , E. Schoell
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