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Subthreshold oscillations in neurons are those oscillations which do not attain the critical value of the membrane's voltage needed for triggering an action potential (a spike). Their contribution to the forming of action potentials in…

Dynamical Systems · Mathematics 2024-03-22 G. Moza , R. Efrem

Many cellular functions are based on the rhythmic organization of biological processes into self-repeating cascades of events. Some of these periodic processes, such as the cell cycles of several species, exhibit conspicuous irregularities…

Molecular Networks · Quantitative Biology 2011-09-30 Pau Rué , Gürol M. Süel , Jordi Garcia-Ojalvo

First return maps of interspike intervals for biological neurons that generate repetitive bursts of impulses can display stereotyped structures (neuronal signatures). Such structures have been linked to the possibility of multicoding and…

Neurons and Cognition · Quantitative Biology 2015-06-22 Bóris Marin , Reynaldo Daniel Pinto , Robert C Elson , Eduardo Colli

The effect of demographic stochasticity, in the form of Gaussian white noise, in a predator-prey model with one fast and two slow variables is studied. We derive the stochastic differential equations (SDEs) from a discrete model. For…

Dynamical Systems · Mathematics 2018-12-24 Susmita Sadhu , Christian Kuehn

Computer musicians refer to mesostructures as the intermediate levels of articulation between the microstructure of waveshapes and the macrostructure of musical forms. Examples of mesostructures include melody, arpeggios, syncopation,…

Sound · Computer Science 2023-01-25 Cyrus Vahidi , Han Han , Changhong Wang , Mathieu Lagrange , György Fazekas , Vincent Lostanlen

Noise-induced transitions between metastable fixed points in systems evolving on multiple time scales are analyzed in situations where the time scale separation gives rise to a slow manifold with bifurcation. This analysis is performed…

Statistical Mechanics · Physics 2017-10-05 Tobias Grafke , Eric Vanden-Eijnden

The three-dimensional (3D) Fitzhugh-Nagumo neuron model with inertia was shown to exhibit a chaotic mixed-mode dynamics composed of large-amplitude spikes separated by an irregular number of small-amplitude chaotic oscillations. In contrast…

Adaptation and Self-Organizing Systems · Physics 2023-01-25 Marzena Ciszak , Salvador Balle , Oreste Piro , Francesco Marino

We study the impact of noise on a neural population rate model of up and down states. Up and down states are typically observed in neuronal networks as a slow oscillation, where the population switches between high and low firing rates…

Neurons and Cognition · Quantitative Biology 2015-04-24 Zachary McCleney , Zachary P. Kilpatrick

The effects of noise on the dynamics of nonlinear systems is known to lead to many counter-intuitive behaviors. Using simple planar limit cycle oscillators, we show that the addition of moderate noise leads to qualitatively different…

Chaotic Dynamics · Physics 2015-06-17 Jay M. Newby , Michael A. Schwemmer

We investigate the stimulus-dependent tuning properties of a noisy ionic conductance model for intrinsic subthreshold oscillations in membrane potential and associated spike generation. On depolarization by an applied current, the model…

Neurons and Cognition · Quantitative Biology 2009-11-11 Martin Tobias Huber And Hans Albert Braun

The activity generated by an ensemble of neurons is affected by various noise sources. It is a well-recognised challenge to understand the effects of noise on the stability of such networks. We demonstrate that the patterns of activity…

Analysis of PDEs · Mathematics 2022-05-19 Jose A. Carrillo , Helge Holden , Susanne Solem

By varying the noise intensity, we study stochastic spiking coherence (i.e., collective coherence between noise-induced neural spikings) in an inhibitory population of subthreshold neurons (which cannot fire spontaneously without noise).…

Biological Physics · Physics 2011-11-01 Woochang Lim , Sang-Yoon Kim

At functional scales, cortical behavior results from the complex interplay of a large number of excitable cells operating in noisy environments. Such systems resist to mathematical analysis, and computational neurosciences have largely…

Neurons and Cognition · Quantitative Biology 2014-03-05 Mathieu Galtier , Jonathan Touboul

Brain functions require both segregated processing of information in specialized circuits, as well as integration across circuits to perform high-level information processing. One possible way to implement these seemingly opposing demands…

We study stochastic dynamics of an ensemble of N globally coupled excitable elements. Each element is modeled by a FitzHugh-Nagumo oscillator and is disturbed by independent Gaussian noise. In simulations of the Langevin dynamics we…

Statistical Mechanics · Physics 2009-11-11 M. Zaks , X. Sailer , L. Schimansky-Geier , A. Neiman

We study the effects of noise on a recently discovered form of intermittency, referred to as in-out intermittency. This type of intermittency, which reduces to on-off in systems with a skew product structure, has been found in the dynamics…

Chaotic Dynamics · Physics 2009-11-07 Peter Ashwin , Eurico Covas , Reza Tavakol

In this paper, we use geometric singular perturbation theory and blowup, as our main technical tool, to study the mixed-mode oscillations (MMOs) that occur in two coupled FitzHugh-Nagumo units with symmetric and repulsive coupling. In…

Dynamical Systems · Mathematics 2022-11-18 Kristian Uldall Kristiansen , Morten Gram Pedersen

When modelling time series, it is common to decompose observed variation into a "signal" process, the process of interest, and "noise", representing nuisance factors that obfuscate the signal. To separate signal from noise, assumptions must…

Methodology · Statistics 2020-11-11 Richard Creswell , Ben Lambert , Chon Lok Lei , Martin Robinson , David Gavaghan

An approach is suggested for treating multiscale fluctuations in macromolecular systems. The emphasis is on the statistical properties of such fluctuations. The approach is illustrated by a macromolecular system with mesoscopic fluctuations…

Chemical Physics · Physics 2012-08-07 V. I. Yukalov , E. P. Yukalova

We consider a model of a square-wave bursting neuron residing in the regime of tonic spiking. Upon introduction of small stochastic forcing, the model generates irregular bursting. The statistical properties of the emergent bursting…

Adaptation and Self-Organizing Systems · Physics 2008-11-11 Pawel Hitczenko , Georgi S. Medvedev