Related papers: Scalable, Time-Responsive, Digital, Energy-Efficie…
We provide an overview of current approaches to DNA-based storage system design and accompanying synthesis, sequencing and editing methods. We also introduce and analyze a suite of new constrained coding schemes for both archival and random…
Porous electrode theory (PET) provides essential insights into electrochemical states, but its computational complexity hinders real-time control and obscures scaling relations. To bridge the gap between high-fidelity simulations and…
Model-based design of experiments (MBDOE) is essential for efficient parameter estimation in nonlinear dynamical systems. However, conventional adaptive MBDOE requires costly posterior inference and design optimization between each…
Binary Decision Diagrams (BDDs) are instrumental in many electronic design automation (EDA) tasks thanks to their compact representation of Boolean functions. In BDD-based reversible-circuit synthesis, which is critical for quantum…
In this paper, we consider the outer channel for DNA-based data storage. When transmitting over the outer channel, each DNA string is treated as a unit/symbol that would be either correctly received, or erased, or corrupted by uniformly…
An exact, analytic solution for a simple electrostatic model applicable to biomolecular recognition is presented. In the model, a layer of high dielectric constant material (representative of the solvent, water) whose thickness may vary…
Superconducting electronics is essential for energy-efficient quantum and classical high-end computing applications. Towards this goal, non-reciprocal superconducting circuit elements, such as superconducting diodes (SDs) can fulfill many…
In this paper, we present the design of a Deoxyribonucleic Acid (DNA) shearing system based on unique acoustic waves generated using a phased-array Fresnel Lens transducer. Four 90-degree sector-transducers are used to build a circular…
Charge migration along DNA molecules has attracted scientific interest for over half a century. Reports on possible high rates of charge transfer between donor and acceptor through the DNA, obtained in the last decade from solution…
In this short note, a correction is made to the recently proposed solution [1] to a 1D biased diffusion model for linear DNA translocation and a new analysis will be given to the data in [1]. It was pointed out [2] by us recently that this…
In recent years, reversible logic has emerged as a promising computing paradigm having its applications in low power computing, quantum computing, nanotechnology, optical computing and DNA computing. The classical set of gates such as AND,…
Learned Differentiable Boolean Logic Networks (DBNs) already deliver efficient inference on resource-constrained hardware. We extend them with a trainable, differentiable interconnect whose parameter count remains constant as input width…
This paper presents a gate-level Boolean evolutionary geometric attention neural network that models images as Boolean fields governed by logic gates. Each pixel is a Boolean variable (0 or 1) embedded on a two-dimensional geometric…
Messenger RNA (mRNA) sequences as therapeutics require optimized design to ensure efficient translation, structural stability, and minimal immunogenicity. This study presents a two-stage in-silico framework that integrates deep learning and…
DNA Data storage has recently attracted much attention due to its durable preservation and extremely high information density (bits per gram) properties. In this work, we propose a hybrid coding strategy comprising of generalized…
Rapid and cost-effective DNA sequencing at the single nucleotide level might be achieved by measuring a transverse electronic current as single-stranded DNA is pulled through a nano-sized pore. In order to enhance the electronic coupling…
In equilibrium self-assembly, microscopic building blocks spontaneously self-organize into stable structures as dictated by their interaction potentials, which limits the accessible structural features to those that correspond to global…
Due to energy-efficiency requirements, computational systems are now being implemented using noisy nanoscale semiconductor devices whose reliability depends on energy consumed. We study circuit-level energy-reliability limits for deep…
We have developed a quantum annealing processor, based on an array of tunably coupled rf-SQUID flux qubits, fabricated in a superconducting integrated circuit process [1]. Implementing this type of processor at a scale of 512 qubits and…
The liquid-liquid phase separation of biomolecules is an important process for intracellular organization. Biomolecular sequence combinatorics leads to a large variety of proteins and nucleic acids which can interact to form a diversity of…