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Quorum sensing is a decentralized biological process, through which a community of cells with no global awareness coordinate their functional behaviors based solely on cell-medium interactions and local decisions. This paper draws…

Machine Learning · Computer Science 2015-10-08 Feng Tan , Jean-Jacques Slotine

This paper describes two approaches for fault detection: an immune-based mechanism and a formal language algorithm. The first one is based on the feature of immune systems in distinguish any foreign cell from the body own cell. The formal…

Computational Engineering, Finance, and Science · Computer Science 2016-11-17 J. F. Martins , P. J. Costa Branco , A. J. Pires , J. A. Dente

In this paper, we propose a new methodology based on the Negative Selection Algorithm that belongs to the field of Computational Intelligence, specifically, Artificial Immune Systems to identify takeover targets. Although considerable…

Artificial Intelligence · Computer Science 2013-08-13 Satyakama Paul , Andreas Janecek , Fernando Buarque de Lima Neto , Tshilidzi Marwala

In the realm of IoT/CPS systems connected over mobile networks, traditional intrusion detection methods analyze network traffic across multiple devices using anomaly detection techniques to flag potential security threats. However, these…

Cryptography and Security · Computer Science 2024-10-07 Anantaa Kotal , Brandon Luton , Anupam Joshi

This paper develops a mathematical and computational framework for analyzing the expected performance of Bayesian data fusion, or joint statistical inference, within a sensor network. We use variational techniques to obtain the posterior…

Statistics Theory · Mathematics 2016-02-23 Gaurav Thakur

As one of the emerging algorithms in the field of Artificial Immune Systems (AIS), the Dendritic Cell Algorithm (DCA) has been successfully applied to a number of challenging real-world problems. However, one criticism is the lack of a…

Neural and Evolutionary Computing · Computer Science 2013-06-03 Feng Gu , Julie Greensmith , Uwe Aickelin

Some cells have to take decision based on the quality of surroundings ligands, almost irrespective of their quantity, a problem we name "absolute discrimination". An example of absolute discrimination is recognition of not-self by immune T…

Cell Behavior · Quantitative Biology 2016-02-17 Paul François , Grégoire Altan-Bonnet

Hacking and false data injection from adversaries can threaten power grids' everyday operations and cause significant economic loss. Anomaly detection in power grids aims to detect and discriminate anomalies caused by cyber attacks against…

Machine Learning · Computer Science 2023-03-14 Xijuan Sun , Di Wu , Arnaud Zinflou , Benoit Boulet

Endpoint Detection and Response (EDR) solutions embrace the method of attack provenance graph to discover unknown threats through system event correlation. However, this method still faces some unsolved problems in the fields of…

Cryptography and Security · Computer Science 2026-02-18 Peilun Wu , Nan Sun , Nour Moustafa , Youyang Qu , Ming Ding

Anomaly detection is a significant and hence well-studied problem. However, developing effective anomaly detection methods for complex and high-dimensional data remains a challenge. As Generative Adversarial Networks (GANs) are able to…

Machine Learning · Computer Science 2018-12-07 Houssam Zenati , Manon Romain , Chuan Sheng Foo , Bruno Lecouat , Vijay Ramaseshan Chandrasekhar

Cellular nuclei recognition serves as a fundamental and essential step in the workflow of digital pathology. However, with disparate source organs and staining procedures among histology image clusters, the scanned tiles inherently conform…

Quantitative Methods · Quantitative Biology 2024-07-22 Jianan Fan , Dongnan Liu , Canran Li , Hang Chang , Heng Huang , Filip Braet , Mei Chen , Weidong Cai

The brain is a highly efficient system evolved to achieve high performance with limited resources. We propose that dendrites make information processing and storage in the brain more efficient through the segregation of inputs and their…

Neurons and Cognition · Quantitative Biology 2023-06-13 Roman Makarov , Michalis Pagkalos , Panayiota Poirazi

In this correspondence we study the problem of channel-aware decision fusion when the sensor detection probability is not known at the decision fusion center. Several alternatives proposed in the literature are compared and new fusion rules…

Information Theory · Computer Science 2016-03-11 Domenico Ciuonzo , Pierluigi Salvo Rossi

Network intrusion detection systems have become a crucial issue for computer systems security infrastructures. Different methods and algorithms are developed and proposed in recent years to improve intrusion detection systems. The most…

Artificial Intelligence · Computer Science 2012-09-06 Ehsan Saboori , Shafigh Parsazad , Yasaman Sanatkhani

Deep neural networks (DNNs) have achieved excellent performance on several tasks and have been widely applied in both academia and industry. However, DNNs are vulnerable to adversarial machine learning attacks, in which noise is added to…

Machine Learning · Computer Science 2020-01-01 Huy H. Nguyen , Minoru Kuribayashi , Junichi Yamagishi , Isao Echizen

Nowadays it is very important to maintain a high level security to ensure safe and trusted communication of information between various organizations. But secured data communication over internet and any other network is always under threat…

Cryptography and Security · Computer Science 2012-04-09 Mohammad Sazzadul Hoque , Md. Abdul Mukit , Md. Abu Naser Bikas

Detecting anomalous inputs, such as adversarial and out-of-distribution (OOD) inputs, is critical for classifiers (including deep neural networks or DNNs) deployed in real-world applications. While prior works have proposed various methods…

Machine Learning · Computer Science 2021-06-18 Jayaram Raghuram , Varun Chandrasekaran , Somesh Jha , Suman Banerjee

In the recent years, therapeutic use of antibodies has seen a huge growth, due to their inherent proprieties and technological advances in the methods used to study and characterize them. Effective design and engineering of antibodies for…

Biomolecules · Quantitative Biology 2020-05-08 Francesco Ambrosetti , Zuzana Jandova , Alexandre M. J. J. Bonvin

Immune cells recognize and discriminate antigens through immunological synapses - dynamic intercellular junctions exhibiting highly organized receptor-ligand patterns. While much work has focused on molecular kinetics and passive mechanisms…

Cell Behavior · Quantitative Biology 2025-10-22 Tony Wong , Tom Chou , Suraj Shankar , Shenshen Wang

In this paper we introduce a new method for detecting outliers in a set of proportions. It is based on the construction of a suitable two-way contingency table and on the application of an algorithm for the detection of outlying cells in…

Methodology · Statistics 2016-08-04 Flavio Mignone , Fabio Rapallo