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In the quest for enhanced HIV prevention methods, the advent of antiretroviral drugs as pre-exposure prophylaxis (PrEP) has marked a significant stride forward. However, the ethical challenges in conducting placebo-controlled trials for new…

Methodology · Statistics 2024-07-09 Fei Gao , Holly Janes , Susan Buchbinder , Deborah Donnell

Respondent-driven sampling (RDS) is a procedure to sample from hard-to-reach populations. It has been widely used in several countries, especially in the monitoring of HIV/AIDS and other sexually transmitted infections. Hard-to-reach…

Applications · Statistics 2012-06-26 Leonardo S. Bastos , Adriana A. Pinho , Claudia Codeço , Francisco I. Bastos

Data dispersed across multiple files are commonly integrated through probabilistic linkage methods, where even minimal error rates in record matching can significantly contaminate subsequent statistical analyses. In regression problems, we…

Statistics Theory · Mathematics 2024-09-18 Abhisek Chakraborty , Saptati Datta

In this paper, we present a new variable selection method for regression and classification purposes. Our method, called Subsampling Ranking Forward selection (SuRF), is based on LASSO penalised regression, subsampling and forward-selection…

Methodology · Statistics 2021-05-25 Lihui Liu , Hong Gu , Johan Van Limbergen , Toby Kenney

We present a comprehensive framework for structured sparse coding and modeling extending the recent ideas of using learnable fast regressors to approximate exact sparse codes. For this purpose, we develop a novel block-coordinate proximal…

Machine Learning · Computer Science 2012-06-22 Alex Bronstein , Pablo Sprechmann , Guillermo Sapiro

The use of M-estimators in generalized linear regression models in high dimensional settings requires risk minimization with hard $L_0$ constraints. Of the known methods, the class of projected gradient descent (also known as iterative hard…

Machine Learning · Computer Science 2014-10-22 Prateek Jain , Ambuj Tewari , Purushottam Kar

While the SLIM approach obtained high ranking-accuracy in many experiments in the literature, it is also known for its high computational cost of learning its parameters from data. For this reason, we focus in this paper on variants of…

Information Retrieval · Computer Science 2019-05-01 Harald Steck

Respondent-Driven Sampling (RDS) is a variant of link-tracing sampling techniques that aim to recruit hard-to-reach populations by leveraging individuals' social relationships. As such, an RDS sample has a graphical component which…

Distribution Regression (DR) on stochastic processes describes the learning task of regression on collections of time series. Path signatures, a technique prevalent in stochastic analysis, have been used to solve the DR problem. Recent…

Machine Learning · Computer Science 2024-10-15 Andrew Alden , Carmine Ventre , Blanka Horvath

The Population-based HIV Impact Assessment (PHIA) is an ongoing project that conducts nationally representative HIV-focused surveys for measuring national and regional progress toward UNAIDS' 90-90-90 targets, the primary strategy to end…

Methodology · Statistics 2022-02-15 Le Bao , Changcheng Li , Runze Li , Songshan Yang

Modeling viral dynamics in HIV/AIDS studies has resulted in a deep understanding of pathogenesis of HIV infection from which novel antiviral treatment guidance and strategies have been derived. Viral dynamics models based on nonlinear…

Applications · Statistics 2010-10-08 Hua Liang , Hongyu Miao , Hulin Wu

Dynamic models have been successfully used in producing estimates of HIV epidemics at national level, due to their epidemiological nature and their ability to simultaneously estimate prevalence, incidence, and mortality rates. Recently, HIV…

Methodology · Statistics 2016-02-19 Le Bao , Ben Sheng , Xiaoyue Niu , Yuan Tang , Tim Brown , Peter D. Ghys , Jeff W. Eaton

Modern statistical applications involving large data sets have focused attention on statistical methodologies which are both efficient computationally and able to deal with the screening of large numbers of different candidate models. Here…

Methodology · Statistics 2014-02-26 David J. Nott , Minh-Ngoc Tran , Chenlei Leng

HIV dynamic studies have contributed significantly to the understanding of HIV pathogenesis and antiviral treatment strategies for AIDS patients. Establishing the relationship of virologic responses with clinical factors and covariates…

Applications · Statistics 2011-04-19 Yangxin Huang , Hulin Wu , Jeanne Holden-Wiltse , Edward P. Acosta

High-dimensional regression and regression with a left-censored response are each well-studied topics. In spite of this, few methods have been proposed which deal with both of these complications simultaneously. The Tobit model -- long the…

Methodology · Statistics 2023-03-20 Tate Jacobson , Hui Zou

We consider high dimensional sparse regression, and develop strategies able to deal with arbitrary -- possibly, severe or coordinated -- errors in the covariance matrix $X$. These may come from corrupted data, persistent experimental…

Machine Learning · Statistics 2013-01-15 Yudong Chen , Constantine Caramanis , Shie Mannor

TechStep is a randomized trial of a mobile health interventions targeted towards transgender adolescents. The interventions include a short message system, a mobile-optimized web application, and electronic counseling. The primary outcomes…

Applications · Statistics 2020-03-24 David Benkeser , Keith Horvath , Cathy Reback , Joshua Rusow , Michael Hudgens

In regression modelling approach, the main step is to fit the regression line as close as possible to the target variable. In this process most algorithms try to fit all of the data in a single line and hence fitting all parts of target…

Machine Learning · Statistics 2018-05-07 Kumarjit Pathak , Jitin Kapila , Aasheesh Barvey , Nikit Gawande

We discuss methods for {\em a priori} selection of parameters to be estimated in inverse problem formulations (such as Maximum Likelihood, Ordinary and Generalized Least Squares) for dynamical systems with numerous state variables and an…

Quantitative Methods · Quantitative Biology 2020-04-20 H. T. Banks , Ariel Cintrón-Arias

We study minimal mean-field models of viral drug resistance development in which the efficacy of a therapy is described by a one-dimensional stochastic resetting process with mixed reflecting-absorbing boundary conditions. We derive…