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We develop an iterative global solution scheme for the backward Kolmogorov equation of the diffusion approximation of the Wright-Fisher model of population genetics. That model describes the random genetic drift of several alleles at the…

Analysis of PDEs · Mathematics 2014-06-20 Julian Hofrichter , Tat Dat Tran , Jürgen Jost

Wright-Fisher diffusions and their dual ancestral graphs occupy a central role in the study of allele frequency change and genealogical structure, and they provide expressions, explicit in some special cases but generally implicit, for the…

Probability · Mathematics 2025-03-25 Martina Favero , Paul A. Jenkins

Known results on the moments of the distribution generated by the two-locus Wright-Fisher diffusion model and a duality between the diffusion process and the ancestral process with recombination are briefly summarized. A numerical methods…

Populations and Evolution · Quantitative Biology 2013-04-08 Shuhei Mano

The long time behavior of an absorbed Markov process is well described by the limiting distribution of the process conditioned to not be killed when it is observed. Our aim is to give an approximation's method of this limit, when the…

Probability · Mathematics 2009-05-25 Denis Villemonais

We investigate various aspects of the (biallelic) Wright-Fisher diffusion with seed bank in conjunction with and contrast to the two-island model analysed e.g. in Kermany, Zhou and Hickey, 2008, and Nath and Griffiths, 1993, including…

Motivated by a down-up Markov chain on cladograms, David Aldous conjectured in 1999 that there exists a "diffusion on continuum trees" whose mass partitions at any finite number of branch points evolve as Wright-Fisher diffusions with some…

Probability · Mathematics 2023-05-30 Noah Forman , Soumik Pal , Douglas Rizzolo , Matthias Winkel

In this paper, we propose a drift-diffusion process on the probability simplex to study stochastic fluctuations in probability spaces. We construct a counting process for linear detailed balanced chemical reactions with finite species such…

Probability · Mathematics 2024-08-19 Yuan Gao , Wuchen Li , Jian-Guo Liu

We apply a Lindeberg principle under the Markov process setting to approximate the Wright-Fisher model with neutral $r$-alleles using a diffusion process, deriving an error rate based on a function class distance involving fourth-order…

Probability · Mathematics 2024-07-15 Peng Chen , Jie Xiong , Lihu Xu , Jiayu Zheng

To model discrete sequences such as DNA, proteins, and language using diffusion, practitioners must choose between three major methods: diffusion in discrete space, Gaussian diffusion in Euclidean space, or diffusion on the simplex. Despite…

We introduce a multi-allele Wright-Fisher model with non-recurrent, reversible mutation and directional selection. In this setting, the allele frequencies at a single locus track the path of a hybrid jump-diffusion process with state space…

Probability · Mathematics 2023-02-16 Ingemar Kaj , Carina F. Mugal , Rebekka Müller

A generalised one-dimensional Fisher-Wright diffusion process with mutations is considered. This is a well-known model in population genetics. An exponential recurrence is established for the process, which also implies an exponential rate…

Probability · Mathematics 2025-03-27 Roman Sineokiy , Alexander Veretennikov

We study the fixation and stationary behavior of the Lambda-Wright-Fisher process with parent-independent mutation and finitely many types, a jump-diffusion model for allele frequency dynamics in large populations with potentially large…

Probability · Mathematics 2025-09-19 Airam Blancas , Adrián González Casanova , Sebastian Hummel , Sandra Palau

Under the effect of strong genetic drift, it is highly probable to observe gene fixation or gene loss in a population, shown by infinite peaks on a coherently constructed potential energy landscape. It is then important to ask what such…

Populations and Evolution · Quantitative Biology 2015-06-15 Song Xu , Shuyun Jiao , Pengyao Jiang , Ping Ao

We study the evolution of a pathogen with two allelic types infecting a population of hosts, where within-host type frequencies evolve in discrete time. Our framework is built on a two-parameter family of transition kernels on [0,1], which…

Probability · Mathematics 2025-11-19 Fernando Cordero , Christian Jorquera , Héctor Olivero , Leonardo Videla

We consider diffusion processes x_{t} on the unit interval. Doob-transformation techniques consist of a selection of x_{t}-paths procedure. The law of the transformed process is the one of a branching diffusion system of particles, each…

Quantitative Methods · Quantitative Biology 2011-07-15 Thierry Huillet

In a (two-type) Wright-Fisher diffusion with directional selection and two-way mutation, let $x$ denote today's frequency of the beneficial type, and given $x$, let $h(x)$ be the probability that, among all individuals of today's…

Populations and Evolution · Quantitative Biology 2015-07-10 Ute Lenz , Sandra Kluth , Ellen Baake , Anton Wakolbinger

A new class of time-dependent Dirichlet priors is introduced as a generalisation of the Wright-Fisher diffusion, allowing discontinuities in the trajectories, as well as non-Markovian memory. This class is obtained as a simple stochastic…

Statistics Theory · Mathematics 2026-04-14 Nathan A. Judd , Dario Spanò

We investigate spatial evolutionary games with death-birth updating in large finite populations. Within growing spatial structures subject to appropriate conditions, the density processes of a fixed type are proven to converge to the…

Probability · Mathematics 2017-05-23 Yu-Ting Chen

We develop a global and hierarchical scheme for the forward Kolmogorov (Fokker-Planck) equation of the diffusion approximation of the Wright-Fisher model of population genetics. That model describes the random genetic drift of several…

Analysis of PDEs · Mathematics 2015-09-21 Julian Hofrichter , Tat Dat Tran , Jürgen Jost

The two-parameter Poisson--Dirichlet diffusion, introduced in 2009 by Petrov, extends the infinitely-many-neutral-alleles diffusion model, related to Kingman's one-parameter Poisson--Dirichlet distribution and to certain Fleming--Viot…