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We discover a new type of nonequilibrium phase transition in a model of chromatin dynamics, which accounts for the coherent motions that have been observed in experiment. The coherent motion is due to the long-range cooperation of molecular…

Soft Condensed Matter · Physics 2023-07-27 Iraj Eshghi , Alexanda Zidovska , Alexander Y. Grosberg

In this paper we study the role of topology in DNA gel electrophoresis experiments via molecular dynamics simulations. The gel is modelled as a 3D array of obstacles from which half edges are removed at random with probability p, thereby…

Soft Condensed Matter · Physics 2015-04-10 Davide Michieletto , Marco Baiesi , Enzo Orlandini , Matthew S. Turner

We have developed a theory of polymer entanglement using an extended Cahn-Hilliard functional, with two extra terms. One is a nonlocal attractive term, operating over mesoscales, which is interpreted as giving rise to entanglement, and the…

Soft Condensed Matter · Physics 2009-10-31 Shirish M. Chitanvis

Loop formation between monomers in the interior of semiflexible chains describes elementary events in biomolecular folding and DNA bending. We calculate analytically the interior distance distribution function for semiflexible chains using…

Soft Condensed Matter · Physics 2009-11-11 Changbong Hyeon , D. Thirumalai

We study the effect of the crowded nature of the cellular cytoplasm on the translocation of a polymer through a pore in a membrane. By systematically treating the entropic penalty due to crowding, we show that the translocation dynamics are…

Soft Condensed Matter · Physics 2009-11-13 Ajay Gopinathan , Yong Woon Kim

A ring polymer is a random walk whose steps obey a single linear condition; their sum vanishes. Factoring the graph Laplacian into the product of the incidence matrix and its transpose allows us to show that for a more complicated network,…

Statistical Mechanics · Physics 2025-10-20 Jason Cantarella , Tetsuo Deguchi , Clayton Shonkwiler , Erica Uehara

We consider the statistical mechanics of a system of topologically linked polymers, such as for instance a dense solution of polymer rings. If the possible topological states of the system are distinguished using the Gauss linking number as…

Statistical Mechanics · Physics 2010-01-05 Franco Ferrari

The population-averaged contact maps generated by the chromosome conformation capture technique provide important information about the average frequency of contact between pairs of chromatin loci as a function of the genetic distance…

Statistical Mechanics · Physics 2024-04-09 Dmitry Starkov , Sergey Belan

We study theoretically layered spin systems where long-range dipolar interactions play a relevant role. By choosing a specific sample shape, we are able to reduce the complex Hamiltonian of the system to that of a much simpler coupled…

Statistical Mechanics · Physics 2009-11-11 Alessandro Campa , Ramaz Khomeriki , David Mukamel , Stefano Ruffo

We study the motion of dispersed nanoprobes in entangled active-passive polymer mixtures. By comparing the two architectures of linear vs. unconcatenated and unknotted circular polymers, we demonstrate that novel, rich physics emerge. For…

Soft Condensed Matter · Physics 2021-08-27 Andrea Papale , Jan Smrek , Angelo Rosa

The statistics of randomly branching double-folded ring polymers are relevant to the secondary structure of RNA, the large-scale branching of plectonemic DNA (and thus bacterial chromosomes), the conformations of single-ring polymers…

Soft Condensed Matter · Physics 2025-10-03 Elham Ghobadpour , Max Kolb , Ivan Junier , Ralf Everaers

We study, the interplay between topology and electron-electron interactions in the moir\'{e} MoTe\(_2\)/WSe\(_2\) heterobilayer. In our analysis we apply an effective two-band model with complex hoppings that incorporates the Ising-type…

Strongly Correlated Electrons · Physics 2025-10-03 Palash Saha , Louk Rademaker , Michał Zegrodnik

The number of configurations of a polymer is reduced in the presence of a barrier or an obstacle. The resulting loss of entropy adds a repulsive component to other forces generated by interaction potentials. When the obstructions are scale…

Soft Condensed Matter · Physics 2015-06-11 Mohammad F. Maghrebi , Yacov Kantor , Mehran Kardar

Motivated by recent observations that non-concatenated ring polymers in their dense solution exhibit a glass-like dynamics, we propose a free volume description of the motion of such rings based on the notion of topological volume. We first…

Soft Condensed Matter · Physics 2018-10-03 Takahiro Sakaue

The conformational statistics of ring polymers in melts or dense solutions is strongly affected by their quenched microscopic topological state. The effect is particularly strong for untangled (i.e. non-concatenated and unknotted) rings,…

Soft Condensed Matter · Physics 2019-03-14 Raoul D. Schram , Angelo Rosa , Ralf Everaers

Polymer entanglements lead to complicated topological constraints and interactions between neighbouring chains in a dense solution or melt. Entanglements can be treated in a mean field approach, within the famous reptation model, since they…

Soft Condensed Matter · Physics 2007-05-23 S. Kutter , E. M. Terentjev

Strong coupling phenomena, such as the like charged macroions attraction, opposite charged macroions repulsion, charge renormalization or charge inversion, are known to be mediated by multivalent counterions. Most theories treat the…

Soft Condensed Matter · Physics 2016-02-03 Sandipan Dutta , Y. S. Jho

We use numerical simulations to study tangentially active flexible ring polymers with different knot topologies. Simple, unknotted active rings display a transition from an extended phase to a collapsed one upon increasing the degree of…

Soft Condensed Matter · Physics 2025-08-01 Davide Breoni , Emanuele Locatelli , Luca Tubiana

Topological entanglements severely interfere with important biological processes. For this reason, genomes must be kept unknotted and unlinked during most of a cell cycle. Type II Topoisomerase (TopoII) enzymes play an important role in…

Soft Condensed Matter · Physics 2022-10-12 Enzo Orlandini , Davide Marenduzzo , Davide Michieletto

Polymers in a melt may be subject to topological constraints, as in the example of unlinked polymer rings. How to do statistical mechanics in the presence of such constraints remains a fundamental open problem. We study the effect of…

Statistical Mechanics · Physics 2015-12-04 Pablo Serna , Guy Bunin , Adam Nahum