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Chromatin remodeling machineries are abundant and diverse in eukaryotic cells. They have been involved in a variety of situations such as histone exchange and DNA repair, but their importance in gene expression remains unclear. Although the…

Molecular Networks · Quantitative Biology 2015-09-25 Denis Michel

Symmetry and topology are fundamental concepts deeply intertwined in various fields of physics, especially in the studies of quantum phases of matter. The critical role that Coulomb interactions play in symmetry breaking during topological…

Mesoscale and Nanoscale Physics · Physics 2026-03-12 Xinghao Wang , Wenfeng Zhang , Yujiang Dong , Weiliang Qiao , Peizhe Jia , Rui-Rui Du

Transcriptional activity has been shown to relate to the organization of chromosomes in the eukaryotic nucleus and in the bacterial nucleoid. In particular, highly transcribed genes, RNA polymerases and transcription factors gather into…

Biological Physics · Physics 2010-05-11 Ivan Junier , Olivier Martin , François Képès

We analyze the probability of a single loop formation in a long flexible polymer chain in disordered environment in $d$ dimensions. The structural defects are considered to be correlated on large distances $r$ according to a power law $\sim…

Soft Condensed Matter · Physics 2016-04-14 K. Haydukivska , V. Blavatska

The interaction of amphiphilic polymers with small colloids, capable to reversibly stick onto the chains, is studied. Adhesive small colloids in solution are able to dynamically bind two polymer segments. This association leads to…

Soft Condensed Matter · Physics 2010-11-10 Vladimir A. Baulin , Albert Johner , Josep Bonet Avalos

Higher-order topological crystalline phases in low-dimensional interacting quantum systems represent a challenging and largely unexplored research topic. Here, we derive a Hamiltonian describing fermions interacting through correlated…

Strongly Correlated Electrons · Physics 2023-01-04 A. Montorsi , U. Bhattacharya , Daniel González-Cuadra , M. Lewenstein , G. Palumbo , L. Barbiero

The translocation of biopolymers, such as DNA and proteins, across cellular or nuclear membranes is essential for numerous biological processes. The translocation dynamics are influenced by the properties of the polymers, such as polymer…

Soft Condensed Matter · Physics 2024-07-29 Gokul Upadhyay , Rajeev Kapri , Anil Kumar Dasanna , Abhishek Chaudhuri

Genome organization in eukaryotes during interphase stems from the delicate balance between non-random correlations present in the DNA polynucleotide linear sequence and the physico/chemical reactions which shape continuously the form and…

Genomics · Quantitative Biology 2020-05-15 Alessandra Merlotti , Angelo Rosa , Daniel Remondini

Using molecular dynamics simulation, we investigate the effect of confinement on a system that comprises several stiff segmented polymer chains where each chain has similar segments, but length and stiffness of the segments vary among the…

Soft Condensed Matter · Physics 2015-07-14 Arash Azari , Kristian K. Müller-Nedebock

Understanding interactions between membranes requires measurements on well-controlled systems close to natural conditions, in which fluctuations play an important role. We have determined, by grazing incidence X-ray scattering, the…

We solve a hydrodynamic model of active chromatin dynamics, within a confined geometry simulating the cell nucleus. Using both analytical and numerical methods, we describe the behavior of the chromatin polymer driven by the activity of…

Soft Condensed Matter · Physics 2023-05-05 Iraj Eshghi , Alexandra Zidovska , Alexander Y. Grosberg

During interphase, a typical cell nucleus features spatial compartmentalization of transcriptionally active euchromatin and repressed heterochromatin domains. In conventional nuclear organization, euchromatin predominantly occupies the…

Soft Condensed Matter · Physics 2025-07-25 Ligesh Theeyancheri , Edward J. Banigan , J. M. Schwarz

We showed in our previous studies that just $3\%$ cross-links, at special points along the contour of the bacterial DNA help the DNA-polymer to get organized at micron length scales \cite{jpcm,epl}. In this work, we investigate how does the…

Soft Condensed Matter · Physics 2019-05-01 Tejal Agarwal , G. P. Manjunath , Farhat Habib , Apratim Chatterji

This work investigates the effects of tangent polar activity on the conformational and dynamic properties of entangled polymer melts through Langevin molecular dynamics simulations. We examine systems composed of all self-propelled,…

Soft Condensed Matter · Physics 2024-11-19 Javier Oller-Iscar , Andrés R. Tejedor , Marisol Ripoll , Jorge Ramírez

Biophysicists are modeling conformations of interphase chromosomes, often basing the strengths of interactions between segments distant on the genetic map on contact frequencies determined experimentally. Here, instead, we develop a…

Biomolecules · Quantitative Biology 2015-11-06 C. A. Brackley , J. Johnson , S. Kelly , P. R. Cook , D. Marenduzzo

We investigate the topological properties of hardcore bosons possessing nearest-neighbor repulsive interactions on a two-leg ladder. We show that by allowing nearest neighbour dimerized interactions instead of hopping dimerization, the…

Quantum Gases · Physics 2024-10-08 Rajashri Parida , Ashirbad Padhan , Tapan Mishra

Contact inhibition is the process by which cells switch from a motile growing state to a passive and stabilized state upon touching their neighbors. When two cells touch, an adhesion link is created between them by means of transmembrane…

Biological Physics · Physics 2015-05-15 Markus Basan , Timon Idema , Martin Lenz , Jean-François Joanny , Thomas Risler

The self-avoid random walk algorithm has been extensively used in the study of polymers. In this work we study the basic properties of the trajectories generated with this algorithm when two interactions are added to it: contact and folding…

Soft Condensed Matter · Physics 2023-04-14 R. J. Santos Neto , A. A. Costa , P. F. Gomes

We demonstrate the generation of high order harmonics in carrier pumping from precessing ferromagnetic or antiferromagnetic orders, excited via magnetic resonance, in the presence of topological antiferromagnetic textures. This results in…

Mesoscale and Nanoscale Physics · Physics 2023-02-15 Ousmane Ly

The interplay between non-trivial band topology and strong electronic correlations is a central challenge in modern condensed matter physics. We investigate this competition on a two-leg ladder model with a p-wave-like hybridisation between…

Strongly Correlated Electrons · Physics 2025-11-13 Aminul Hussain , Nisa Ara , Rudranil Basu , Sudeshna Sen
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