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In this work we examine the properties of a recently described ordinary differential equation that relates the age-specific prevalence of a chronic disease with the incidence and mortalities of the diseased and healthy persons. The equation…

Quantitative Methods · Quantitative Biology 2012-08-28 Ralph Brinks

Measurements are generally collected as unilateral or bilateral data in clinical trials or observational studies. For example, in ophthalmology studies, the primary outcome is often obtained from one eye or both eyes of an individual. In…

Methodology · Statistics 2021-11-01 Kejia Wang , Chang-Xing Ma

Personalized recommendation attracts a surge of interdisciplinary researches. Especially, similarity based methods in applications of real recommendation systems achieve great success. However, the computations of similarities are…

Information Retrieval · Computer Science 2014-07-30 Xuzhen Zhu , Hui Tian , Shimin Cai

In most medical research, the average treatment effect is used to evaluate a treatment's performance. However, precision medicine requires knowledge of individual treatment effects: What is the difference between a unit's measurement under…

Computation · Statistics 2022-08-30 Mingyang Cai , Stef van Buuren , Gerko Vink

We model investor heterogeneity using different required returns on an investment and evaluate the impact on the valuation of an investment. By assuming no disagreement on the cash flows, we emphasize how risk preferences in particular, but…

General Finance · Quantitative Finance 2021-09-13 Carol Alexander , Xi Chen , Charles Ward

Estimating heterogeneous treatment effects is a well-studied topic in the statistics literature. More recently, it has regained attention due to an increasing need for precision medicine as well as the increased use of state-of-art machine…

Methodology · Statistics 2022-10-05 Zhongyuan Chen , Jun Xie

We develop a new classification framework based on the theory of coherent risk measures and systemic risk. The proposed approach is suitable for multi-class problems when the data is noisy, scarce (relative to the dimension of the problem),…

Machine Learning · Statistics 2026-05-29 Darinka Dentcheva , Xiangyu Tian

Commonly used evaluation measures including Recall, Precision, F-Measure and Rand Accuracy are biased and should not be used without clear understanding of the biases, and corresponding identification of chance or base case levels of the…

Machine Learning · Computer Science 2020-11-02 David M. W. Powers

Risk scores are simple classification models that let users make quick risk predictions by adding and subtracting a few small numbers. These models are widely used in medicine and criminal justice, but are difficult to learn from data…

Machine Learning · Statistics 2020-10-21 Berk Ustun , Cynthia Rudin

Credit risk prediction is an effective way of evaluating whether a potential borrower will repay a loan, particularly in peer-to-peer lending where class imbalance problems are prevalent. However, few credit risk prediction models for…

Machine Learning · Computer Science 2018-05-03 Anahita Namvar , Mohammad Siami , Fethi Rabhi , Mohsen Naderpour

Practitioners in diverse fields such as healthcare, economics and education are eager to apply machine learning to improve decision making. The cost and impracticality of performing experiments and a recent monumental increase in electronic…

Machine Learning · Computer Science 2023-08-01 Fredrik D. Johansson , Uri Shalit , Nathan Kallus , David Sontag

Machine learning models are often used to inform real world risk assessment tasks: predicting consumer default risk, predicting whether a person suffers from a serious illness, or predicting a person's risk to appear in court. Given…

Machine Learning · Computer Science 2023-06-27 Jamelle Watson-Daniels , David C. Parkes , Berk Ustun

Aggregated health data such as claims data from health insurances become more and more available for research purposes. Estimates of excess mortality from prevalence and incidence of a chronic condition have only been possible for ages 50…

Populations and Evolution · Quantitative Biology 2019-08-13 Ralph Brinks

Machine learning is used to make decisions for individuals in various fields, which require us to achieve good prediction accuracy while ensuring fairness with respect to sensitive features (e.g., race and gender). This problem, however,…

Machine Learning · Computer Science 2021-03-01 Yoichi Chikahara , Shinsaku Sakaue , Akinori Fujino , Hisashi Kashima

Difference-in-differences is one of the most used identification strategies in empirical work in economics. This chapter reviews a number of important, recent developments related to difference-in-differences. First, this chapter reviews…

Econometrics · Economics 2022-08-02 Brantly Callaway

The increasing ease of data capture and storage has led to a corresponding increase in the choice of data, the type of analysis performed on that data, and the complexity of the analysis performed. The main contribution of this paper is to…

Applications · Statistics 2018-03-14 David Kohn , Nick Glozier , Ian B. Hickie , Hugh Durrant-Whyte , Sally Cripps

Estimating individualized treatment rules (ITRs) is crucial for tailoring interventions in precision medicine. Typical ITR estimation methods rely on conditional average treatment effects (CATEs) to guide treatment assignments. However,…

Methodology · Statistics 2025-10-20 Peng Wu , Qing Jiang , Shanshan Luo , Zhi Geng

Individual probabilities refer to the probabilities of outcomes that are realized only once: the probability that it will rain tomorrow, the probability that Alice will die within the next 12 months, the probability that Bob will be…

Machine Learning · Computer Science 2023-05-09 Aaron Roth , Alexander Tolbert , Scott Weinstein

A common problem in formulating models for the relative risk and risk difference is the variation dependence between these parameters and the baseline risk, which is a nuisance model. We address this problem by proposing the conditional log…

Methodology · Statistics 2016-11-21 Thomas S. Richardson , James M. Robins , Linbo Wang

The rapid growth of e-commerce has made people accustomed to shopping online. Before making purchases on e-commerce websites, most consumers tend to rely on rating scores and review information to make purchase decisions. With this…

Information Retrieval · Computer Science 2020-07-07 Yingqiang Ge , Shuyuan Xu , Shuchang Liu , Zuohui Fu , Fei Sun , Yongfeng Zhang