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Charged Particle Therapy is a technique for cancer treatment that exploits hadron beams, mostly protons and carbons. A critical issue is the monitoring of the dose released by the beam to the tumor and to the surrounding tissues. We present…

Theoretical investigations show that linearly and radially polarized multiterawatt and petawatt laser beams, focused to subwavelength waist radii, can directly accelerate protons and carbon nuclei, over micron-size distances, to the…

Accelerator Physics · Physics 2010-05-25 Y. I. Salamin , Z. Harman , C. H. Keitel

The question of whether or not neutron therapy works has been answered. It is a qualified yes, as is the case with all of radiation therapy. But, neutron therapy has not kept pace with the rest of radiation therapy in terms of beam delivery…

Medical Physics · Physics 2014-09-09 Thomas K. Kroc , James S. Welsh

The laser driven acceleration of ions is considered a promising candidate for an ion source for hadron therapy of oncological diseases. Though proton and carbon ion sources are conventionally used for therapy, other light ions can also be…

To improve the quality of cancer treatment with protons, a translation of X-ray Computed Tomography (CT) images into a map of the proton stopping powers needs to be more accurate. Proton stopping powers determined from CT images have…

Objective: To perform a comprehensive comparative analysis of proton, helium-ion, and carbon-ion computed tomography (CT) as direct imaging modalities for hadron therapy treatment planning, focusing on Relative Stopping Power (RSP)…

Medical Physics · Physics 2026-05-29 Zsófia Jólesz , Gábor Bíró , Gábor Papp , Gergely Gábor Barnaföldi

With the continued evolution of modern radiation therapy towards high precision delivery of high therapeutic doses to the tumour while optimally sparing surrounding healthy tissue, imaging becomes a crucial component to identify the…

Medical Physics · Physics 2018-04-24 Katia Parodi

Proton (and ion) cancer therapy has proven to be an extremely effective even supe-rior method of treatment for some tumors 1-4. A major problem, however, lies in the cost of the particle accelerator facilities; high procurement costs…

Hadrontherapy is an established cancer treatment method that enables a more localized dose deposition compared to conventional radiotherapy, potentially reducing the dose to surrounding healthy tissues in certain clinical cases. However, a…

Instrumentation and Detectors · Physics 2025-07-04 L. Gesson , J. Gross , C. Mozzi , C. Reibel , Ch. Finck , S. Higueret , T. D. Le , E. Traykov , J. C. Thomas , N. Arbor , M. Pullia , G. Harmant , M. Vanstalle

In this paper we present the main ideas and discuss both the feasibility and the conceptual design of a novel hybrid technique and equipment for an experimental cancer therapy based on the simultaneous and/or sequential application of two…

Boron Neutron Capture Therapy (BNCT) is a neutron radiotherapy used to treat tumours cells previously doping with Boron-10. This therapy requires an epithermal neutron beam for the treatment of deep tumours and a thermal beam for shallow…

Instrumentation and Detectors · Physics 2021-06-02 M. Macías , B. Fernández , J. Praena

Radiation therapy with carbon ions is a novel technique of cancer radiotherapy, applicable in particular to treating radioresistant tumours at difficult localisations. Therapy planning, where the medical physicist, following the medical…

Medical Physics · Physics 2014-10-07 Leszek Grzanka

During the past decade, the interaction of high-intensity lasers with solid targets has attracted much interest, regarding its potential in accelerating charged particles. In spite of tremendous progress in laser-plasma based acceleration,…

Accelerator Physics · Physics 2010-12-01 Benjamin J. Galow , Zoltán Harman , Christoph H. Keitel

We present a novel application of Tensor Network methods in cancer treatment as a potential tool to solve the dose optimization problem in radiotherapy. In particular, the Intensity-Modulated Radiation Therapy (IMRT) technique - that allows…

Medical Physics · Physics 2021-08-11 Samuele Cavinato , Timo Felser , Marco Fusella , Marta Paiusco , Simone Montangero

Proton beam therapy can potentially offer improved treatment for cancers of the head and neck and in paediatric patients. There has been a sharp uptake of proton beam therapy in recent years as improved delivery techniques and patient…

Photons are exponentially attenuated in matter producing high doses close to the surface. Therefore they are not well suited for the treatment of deep seated tumours. Charged particles, in contrast, exhibit a sharp increase of ionisation…

Instrumentation and Detectors · Physics 2009-11-06 C. Grupen

Ion sources are key components of accelerators devoted to different types of medical applications: hadron-therapy facilities (accelerating protons or carbon ions), high-intensity accelerators for boron-neutron capture therapy (using intense…

Accelerator Physics · Physics 2018-04-24 Santo Gammino

Hadrontherapy is an emerging technique in cancer therapy that uses beams of charged particles. To meet the improved capability of hadrontherapy in matching the dose release with the cancer position, new dose monitoring techniques need to be…

Stereotactic body radiation therapy (SBRT) refers to focusing high-energy rays in three-dimensional space on the tumor lesion area, reducing the dose received by surrounding normal tissues, which can effectively improve the local control…

Medical Physics · Physics 2024-02-27 Yanqi Zong , Zhengrong Cui , Luqi Lin , Sihao Wang , Yizhi Chen

Photon-counting computed tomography (PCCT) marks a significant advancement over conventional energy-integrating detector (EID) CT systems. This review highlights PCCT's superior spatial and contrast resolution, reduced radiation dose, and…