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The goal of this paper is to explore the possibility to detect and identify bacteria by sensing their odor via fluctuation-enhanced sensing with commercial Taguchi sensors. The fluctuations of the electrical resistance during exposure to…

Instrumentation and Detectors · Physics 2009-01-23 Hung-Chih Chang , Laszlo B. Kish , Maria D. King , Chiman Kwan

We present a new method for detecting and identifying bacteria by measuring impedance fluctuations (impedance noise) caused by ion release by the bacteria during phage infestation. This new method significantly increases the measured signal…

Instrumentation and Detectors · Physics 2014-07-22 Gabor Schmera , Laszlo B. Kish

We discuss some of the fundamental practical limitations of the Fluctuation-Enhanced Sensing of odors and gases. We address resolution, measurement speed, reproducibility, memory and other problems such as humidity. Various techniques and…

Signal Processing · Electrical Eng. & Systems 2021-01-18 Graziella Scandurra , Janusz Smulko , Laszlo B. Kish

We analyze a (symmetrical) two-sensor arrangement with a joint boundary line between the sensors for fluctuation-enhanced sensing. We show a way to separate the adsorption-desorption signal components from the diffusive signal component.…

General Physics · Physics 2008-03-10 Gabor Schmera , Laszlo B. Kish

Fluctuation-enhanced sensing comprises the analysis of the stochastic component of the sensor signal and the utilization of the microscopic dynamics of the interaction between the agent and the sensor. We study the relationship between the…

Data Analysis, Statistics and Probability · Physics 2012-07-13 P. Makra , Z. Topalian , C. G. Granqvist , L. B. Kish , C. Kwan

We present a short survey on fluctuation-enhanced gas sensing. We compare some of its main characteristics with those of classical sensing. We address the problem of linear response, information channel capacity, missed alarms and false…

General Physics · Physics 2009-11-13 L. B. Kish , G. Schmera , Ch. Kwan , J. Smulko , P. Heszler , C. -G. Granqvist

We developed a simple way to generate binary patterns based on spectral slopes in different frequency ranges at fluctuation-enhanced sensing. Such patterns can be considered as binary "fingerprints" of odors. The method has experimentally…

Biological Physics · Physics 2010-01-26 Hung-Chih Chang , Laszlo B. Kish , Maria D. King , Chiman Kwan

An improved method for Fluctuation Enhanced Sensing (FES) is introduced. We enhanced the old binary fingerprinting method, where the fingerprint bit values were +/- 1, by introducing ternary fingerprints utilizing a reference odor. In the…

Signal Processing · Electrical Eng. & Systems 2020-02-12 X. You , L. B. Kish , J. -L. Seguin , M. D. King

We show how frequency fluctuations of a vibrational mode can be separated from other sources of phase noise. The method is based on the analysis of the time dependence of the complex amplitude of forced vibrations. The moments of the…

Mesoscale and Nanoscale Physics · Physics 2015-06-03 Z. A. Maizelis , M. L. Roukes , M. I. Dykman

We use the power density spectra obtained by fluctuation-enhanced sensing of bacterial odors (Escherichia coli and Anthrax-surrogate Bacillus subtilis) to generate new, highly distinguishable, types of patterns based on the average slope of…

General Physics · Physics 2012-02-20 Hung-Chih Chang , Laszlo B. Kish , Maria D. King , Chiman Kwan

We propose a method of spatial resolution enhancement in metrology (thermometry, magnetometry, pH estimation, and similar methods) with blinking fluorescent nanosensors by combining sensing with super-resolution optical fluctuation imaging…

Optics · Physics 2026-05-11 Alexander Mikhalychev , Alex Ulyanenkov

We present a model of a novel measurement scheme to detect small amounts of a gas species via the ground-state fluctuations of the electromagnetic field (dispersion forces) depending on the entire spectral properties of all objects. Here,…

Quantum Physics · Physics 2024-05-13 Eivind Kristen Osestad , Pekka Parviainen , Johannes Fiedler

We probe non-equilibrium properties of an active bacterial bath through measurements of correlations of passive tracer particles and the response function of a driven, optically trapped tracer. These measurements demonstrate violation of…

Soft Condensed Matter · Physics 2009-11-13 D. T. N. Chen , A. W. C. Lau , L. A. Hough , M. F. Islam , M. Goulian , T. C. Lubensky , A. G. Yodh

To mimic the mechanical response of passive biological cilia in complex fluids, we study the bending dynamics of an anchored elastic fiber submitted to a dilute granular suspension under shear. We show that the bending fluctuations of the…

Measuring the resistance fluctuations of gas sensors provides new opportunities to enhance the selectivity and sensitivity of the sensor. Taking advantage of this possibility requires special low-noise measurement hardware and software to…

Instrumentation and Detectors · Physics 2014-03-17 Robert Mingesz , Zoltan Gingl , Akos Kukovecz , Zoltan Konya , Krisztian Kordas , Hannu Moilanen

In this work we focus on how noise propagates in biochemical reaction networks and affects sensitivities of the system. We discover that the stochastic fluctuations can enhance sensitivities in one region of the value of control parameters…

Molecular Networks · Quantitative Biology 2008-06-24 Kyung Hyuk Kim , Hong Qian , Herbert M. Sauro

Single-cell studies often show significant phenotypic variability due to the stochastic nature of intra-cellular biochemical reactions. When the numbers of molecules, e.g., transcription factors and regulatory enzymes, are in low abundance,…

Quantitative Methods · Quantitative Biology 2015-06-17 Kyung Hyuk Kim , Hong Qian , Herbert M. Sauro

We exploit the optical lever principle to detect minute fluctuations of a liquid-air interface. Waves propagating on the interface deflect a specularly reflected laser beam, inducing angular deviations captured by a dual-element photodiode.…

A widely used method to measure the bending rigidity of bilayer membranes is fluctuation spectroscopy, which analyses the thermally-driven membrane undulations of giant unilamellar vesicles recorded with either phase-contrast or confocal…

Biological Physics · Physics 2020-09-21 Hammad A. Faizi , Cody J. Reeves , Vasil N. Georgiev , Petia M. Vlahovska , Rumiana Dimova

We present a generic analytical scheme for the quantification of fluctuations due to bifunctionality-induced signal transduction within the members of bacterial two-component system. The proposed model takes into account post-translational…

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