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Cooperative collective dynamics is a principal determinant of the ability of synthetic micromotors to perform specific functions. However, realizing controllable and predictable collective behavior in complex physiological environments…

Chemical Physics · Physics 2026-02-10 Jiang-Xing Chen , Jia-Qi Hu , Raymond Kapral

We investigate performance and optimization of the "digital" bioanalytical response. Specifically, we consider the recently introduced approach of a partial input conversion into inactive compounds, resulting in the "branch point effect"…

Molecular Networks · Quantitative Biology 2013-05-27 Sergii Domanskyi , Vladimir Privman

This paper proposes the use of Eukaryotic cells, namely astrocytes, to develop logic gates. The logic gates are achieved by manipulating the threshold of Ca$^{2+}$ ion flows between the cells, based on the input signals. Through wet-lab…

Electronic logic gates are the basic building blocks of every computing and micro controlling system. Logic gates are made of switches, such as diodes and transistors. Ion-selective, ionic switches may emulate electronic switches [1-8]. If…

Chemical Physics · Physics 2017-10-11 Haim Grebel

With the advancement of synthetic biology, several new tools have been conceptualized over the years as alternative treatments for current medical procedures. Most of those applications are applied to various chronic diseases. This work…

Biocomputing systems based on engineered bacteria can lead to novel tools for environmental monitoring and detection of metabolic diseases. In this paper, we propose a Bacterial Molecular Computing on a Chip (BMCoC) using microfluidic and…

We review models and approaches for error-control in order to prevent the buildup of noise when gates for digital chemical and biomolecular computing based on (bio)chemical reaction processes are utilized to realize stable, scalable…

Soft Condensed Matter · Physics 2011-02-15 Vladimir Privman

Exploiting the effects of quantum interference we put forward an idea of designing three primary logic gates, OR, AND and NOT, using a benzene molecule. Under a specific molecule-lead interface geometry, anti-resonant states appear which…

Mesoscale and Nanoscale Physics · Physics 2018-09-19 Moumita Patra , Santanu K. Maiti

We demonstrate how a genetic ring oscillator network with quorum sensing feedback can operate as a robust logic gate. Specifically we show how a range of logic functions, namely AND/NAND, OR/NOR and XOR/XNOR, can be realized by the system,…

Biological Physics · Physics 2014-04-14 Vidit Agrawal , Shivpal Singh Kang , Sudeshna Sinha

Quantum Hamiltonian Computing is a recent approach that uses quantum systems, in particular a single molecule, to perform computational tasks. Within this approach, we present explicit methods to construct logic gates using two different…

Quantum Physics · Physics 2019-06-18 Omid Faizy Namarvar , Olivier Giraud , Bertrand Georgeot , Christian Joachim

A classical logic gate connecting input and output light pulses is demonstrated. The gate operation is based on three steps: First, two incoming light pulses are stored in a Bose-Einstein condensate, second, atomic four-wave mixing…

Quantum Physics · Physics 2013-01-03 Christoph Vo , Stefan Riedl , Simon Baur , Gerhard Rempe , Stephan Dürr

We realize a biochemical filtering process by introducing a buffer in a biocatalytic signal-transduction logic system based on the function of an enzyme, esterase. The input, ethyl butyrate, is converted into butyric acid-the output signal,…

Soft Condensed Matter · Physics 2017-09-13 Marcos Pita , Vladimir Privman , Mary A. Arugula , Dmitriy Melnikov , Vera Bocharova , Evgeny Katz

We consider a realization of the XOR logic gate in a process biocatalyzed by an enzyme (here horseradish peroxidase: HRP), the function of which can be inhibited by a substrate (hydrogen peroxide for HRP), when the latter is inputted at…

Soft Condensed Matter · Physics 2011-10-05 Jan Halamek , Vera Bocharova , Mary A. Arugula , Guinevere Strack , Vladimir Privman , Evgeny Katz

Biocomputing technologies exploit biological communication mechanisms involving cell-cell signal propagation to perform computations. Researchers recently worked toward realising logic gates made by neurons to develop novel devices such as…

Emerging Technologies · Computer Science 2022-09-07 Giulio Basso , Michael Taynnan Barros

Processes involving multi-input multi-step reaction cascades are used in developing novel biosensing, biocomputing, and decision making systems. In various applications different changes in responses of the constituent processing steps…

Molecular Networks · Quantitative Biology 2016-08-16 Sergii Domanskyi , Vladimir Privman

We report a realization of an associative memory signal/information processing system based on simple enzyme-catalyzed biochemical reactions. Optically detected chemical output is always obtained in response to the triggering input, but the…

Molecular Networks · Quantitative Biology 2013-04-23 Vera Bocharova , Kevin MacVittie , Soujanya Chinnapareddy , Jan Halamek , Vladimir Privman , Evgeny Katz

The end of Moore's law for CMOS technology has prompted the search for low-power computing alternatives, resulting in several promising proposals based on magnetic logic[1-8]. One approach aims at tailoring arrays of nanomagnetic islands in…

Mesoscale and Nanoscale Physics · Physics 2021-09-08 Pieter Gypens , Jonathan Leliaert , Massimiliano Di Ventra , Bartel Van Waeyenberge , Daniele Pinna

Memristors are promising next-generation memory candidates that are nonvolatile, possess low power requirements and are capable of nanoscale fabrication. In this article we physically realise and describe the use of organic memristors in…

Emerging Technologies · Computer Science 2012-12-17 Victor Erokhin , Gerard David Howard , Andrew Adamatzky

We propose that the behaviour of non-linear media can be controlled automatically through coevolutionary systems. By extension, forms of unconventional computing, i.e., massively parallel non-linear computers, can be realised by such an…

Emerging Technologies · Computer Science 2012-12-13 Christopher Stone , Rita Toth , Ben de Lacy Costello , Larry Bull , Andrew Adamatzky

We describe modeling approaches to a "network" of connected enzyme-catalyzed reactions, with added (bio)chemical processes that introduce biochemical filtering steps into the functioning of such a biocatalytic cascade. Theoretical…

Molecular Networks · Quantitative Biology 2016-12-13 Vladimir Privman