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We study ion pair dissociation in water at ambient conditions using a combination of classical and ab initio approaches. The goal of this study is to disentangle the sources of discrepancy observed in computed potentials of mean force. In…

Chemical Physics · Physics 2021-06-02 Alec Wills , Marivi Fernández-Serra

Accurate modeling of aqueous monovalent ions is essential for understanding the function of biomolecules, such as nucleic acid stability and binding of charged drugs to protein targets. The 1D and 3D reference interaction site models (1D-…

Chemical Physics · Physics 2026-04-09 Felipe Silva Carvalho , Alexander McMahon , David A. Case , Tyler Luchko

The interaction between surface patches of proteins with different surface properties has a vital role to play driving conformational changes of proteins in different salt solutions. We demonstrate the existence of ion-specific attractive…

Soft Condensed Matter · Physics 2012-01-06 Eduardo R. A. Lima , Mathias Boström , Nadine Schwierz , Bo E. Sernelius , Frederico W. Tavares

Ion specificity and related Hofmeister effects, ubiquitous in aqueous systems, can have spectacular consequences in hydrated clays, where ion-specific nanoscale surface forces can determine large scale cohesive, swelling and shrinkage…

Soft Condensed Matter · Physics 2022-12-02 Francis Dragulet , Abhay Goyal , Katerina Ioannidou , Roland J. -M. Pellenq , Emanuela Del Gado

A precise understanding of solvation is essential for rational search and design of electrolytes that can meet performance demands in Li-ion and beyond Li-ion batteries. In the context of Li-O$_2$ batteries, ion pairing is decisive in…

Correlated anion and cation motion can significantly reduce the overall ion conductivity in electrolytes versus the ideal conductivity calculated based on the diffusion constants alone. Using coarse-grained molecular dynamics simulations,…

Soft Condensed Matter · Physics 2020-06-01 Kuan-Hsuan Shen , Lisa M. Hall

Free energies of ionic solvation calculated from computer simulations exhibit a strong system size dependence. We perform a finite-size analysis based on a dielectric-continuum model with periodic boundary conditions. That analysis results…

Chemical Physics · Physics 2009-10-30 Gerhard Hummer , Lawrence R. Pratt , Angel E. Garcia

Within the framework of a functional integral formalism incorporating ionic charge and hard-core (HC) interactions on an equal footing, we formulate a unified theory of equilibrium thermodynamics and ion association in charged solutions.…

Soft Condensed Matter · Physics 2026-02-02 Sahin Buyukdagli

Tasker type III polar terminations of ionic crystals carry a net surface charge as well as a dipole moment and are fundamentally unstable. In contact with electrolytes, such polar surfaces can be stabilized by adsorption of counter ions…

Chemical Physics · Physics 2019-03-22 Thomas Sayer , Michiel Sprik , Chao Zhang

We have studied the dependence of metal oxide properties in molecular dynamics (MD) simulations on the polarizability of oxygen ions. We present studies of both liquid and crystalline structures of silica (SiO2), magnesia (MgO) and alumina…

Materials Science · Physics 2012-11-13 Philipp Beck , Peter Brommer , Johannes Roth , Hans-Rainer Trebin

Solvation of ions is ubiquitous on our planet. Solvated ions have a profound effect on the behavior of ionic solutions, which is crucial in nature and technology. Experimentally, ions have been classified into "structure makers" or…

Soft Condensed Matter · Physics 2021-07-27 Rui Shi , Anthony J. Cooper , Hajime Tanaka

Determining the solvation free energies of single ions in water is one of the most fundamental problems in physical chemistry and yet many unresolved questions remain. In particular, the ability to decompose the solvation free energy into…

Chemical Physics · Physics 2017-11-21 Timothy T. Duignan , Marcel D. Baer , Gregory K. Schenter , Christopher J. Mundy

We present a new polarizable force field for aqueous ions (Li+, Na+, K+, Rb+, Cs+, Mg2+, Ca2+, Sr2+ and Cl-) derived from condensed phase ab-initio calculations. We use Maximally Localized Wannier Functions together with a generalized force…

We study NaCl ion-pair dissociation in a dilute aqueous solution using computer simulations both for the full system with long range Coulomb interactions and for a well chosen reference system with short range intermolecular interactions.…

Chemical Physics · Physics 2021-10-13 Dedi Wang , Renjie Zhao , John D. Weeks , Pratyush Tiwary

The hydration free energies of ions exhibit an approximately quadratic dependence on the ionic charge, as predicted by the Born model. We analyze this behavior using second-order perturbation theory. This provides effective methods to…

chem-ph · Physics 2008-02-03 Gerhard Hummer , Lawrence R. Pratt , Angel E. Garcia

Realistic modeling of ionic systems necessitates taking explicitly account of many-body effects. In molecular dynamics simulations, it is possible to introduce explicitly these effects through the use of additional degrees of freedom. Here…

The structure and interactions in electrolytes at high concentration have implications from energy storage to biomolecular interactions. However many experimental observations are yet to be explained in these mixtures, which are far beyond…

Soft Condensed Matter · Physics 2017-04-05 Alexander Smith , Alpha Lee , Susan Perkin

Room temperature ionic liquids (RTILs) are solvent with unusual properties, which are difficult to characterize experimentally because of their intrinsic complexity (large number of atoms, strong Coulomb interactions). Molecular simulations…

Chemical Physics · Physics 2015-06-01 Mathieu Salanne

Ionic liquid ion sources are a promising technology that can be used for many applications from space propulsion to focused ion beam microetching. Ionic liquid ion sources produce ion beams by extracting single ions and metastable solvated…

Chemical Physics · Physics 2021-11-17 Madeleine Schroeder

We combine molecular dynamics simulations with experiments to estimate solubilities of organic salts in complex growth environments. We predict the solubility by simulations of the growth and dissolution of ions at the crystal surface kink…