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Graph coloring is a fundamental problem in combinatorics with many applications in practice. In this problem, the vertices in a given graph must be colored by using the least number of colors in such a way that a vertex has a different…

Data Structures and Algorithms · Computer Science 2020-08-27 Arda Asik , Ibrahim Bugra Demir , Berker Demirel , Baris Batuhan Topal , Kamer Kaya

Graph neural networks (GNNs) have emerged as powerful tools for learning protein structures by capturing spatial relationships at the residue level. However, existing GNN-based methods often face challenges in learning multiscale…

Machine Learning · Computer Science 2026-02-03 Shih-Hsin Wang , Yuhao Huang , Taos Transue , Justin Baker , Jonathan Forstater , Thomas Strohmer , Bao Wang

Deep neural networks have been applied to a wide range of problems across different application domains with great success. Recently, research into combinatorial optimization problems in particular has generated much interest in the machine…

Machine Learning · Computer Science 2021-08-05 Jason Van Hulse , Joshua S. Friedman

In the big data era, the relationship between entries becomes more and more complex. Many graph (or network) algorithms have already paid attention to dynamic networks, which are more suitable than static ones for fitting the complex…

Machine Learning · Computer Science 2022-11-17 Dongqi Fu , Jingrui He

Graphs as a type of data structure have recently attracted significant attention. Representation learning of geometric graphs has achieved great success in many fields including molecular, social, and financial networks. It is natural to…

Machine Learning · Computer Science 2021-07-08 Tian Xia , Wei-Shinn Ku

Discovering disease pathways, which can be defined as sets of proteins associated with a given disease, is an important problem that has the potential to provide clinically actionable insights for disease diagnosis, prognosis, and…

Molecular Networks · Quantitative Biology 2017-12-05 Monica Agrawal , Marinka Zitnik , Jure Leskovec

PPI network alignment aims to find topological and functional similarities between networks of different species. Several alignment approaches have been proposed. Each of these approaches relies on a different alignment method and uses…

Quantitative Methods · Quantitative Biology 2019-11-25 Sarra Ghanjeti

One of the most influential recent results in network analysis is that many natural networks exhibit a power-law or log-normal degree distribution. This has inspired numerous generative models that match this property. However, more recent…

Data Structures and Algorithms · Computer Science 2011-09-01 Isabelle Stanton , Ali Pinar

We introduce a new distributed algorithm for aligning graphs or finding substructures within a given graph. It is based on the cavity method and is used to study the maximum-clique and the graph-alignment problems in random graphs. The…

Quantitative Methods · Quantitative Biology 2010-04-02 S. Bradde , A. Braunstein , H. Mahmoudi , F. Tria , M. Weigt , R. Zecchina

Numerous social, medical, engineering and biological challenges can be framed as graph-based learning tasks. Here, we propose a new feature based approach to network classification. We show how dynamics on a network can be useful to reveal…

Machine Learning · Statistics 2017-06-01 Leonardo Gutierrez Gomez , Benjamin Chiem , Jean-Charles Delvenne

Over the recent years, Graph Neural Networks have become increasingly popular in network analytic and beyond. With that, their architecture noticeable diverges from the classical multi-layered hierarchical organization of the traditional…

Machine Learning · Computer Science 2021-05-17 Stanislav Sobolevsky

Symmetries found through automorphisms or graph fibrations provide important insights in network analysis. Symmetries identify clusters of robust synchronization in the network which improves the understanding of the functionality of…

Quantitative Methods · Quantitative Biology 2022-07-27 Ian Leifer , David Phillips , Francesco Sorrentino , Hernán A. Makse

Graph neural networks are widely used to learn global representations of graphs, which are then used for regression or classification tasks. Typically, the graphs in such data sets are connected, i.e. each training sample consists of a…

Computational Engineering, Finance, and Science · Computer Science 2022-11-01 Chen Shao , Zhou Chen , Pascal Friederich

Degree ssortativity is the tendency for nodes of high degree (resp.low degree) in a graph to be connected to high degree nodes (resp. to low degree ones). It is sually quantified by the Pearson correlation coefficient of the degree-degree…

Physics and Society · Physics 2017-04-14 Alfonso Allen-Perkins , Juan Manuel Pastor , Ernesto Estrada

The use of graph centrality measures applied to biological networks, such as protein interaction networks, underpins much research into identifying key players within biological processes. This approach however is restricted to dyadic…

Quantitative Methods · Quantitative Biology 2024-10-24 Sarah Lawson , Diane Donovan , James Lefevre

In mathematical phylogenetics, evolutionary relationships are often represented by trees and networks. The latter are typically used whenever the relationships cannot be adequately described by a tree, which happens when so-called…

Populations and Evolution · Quantitative Biology 2025-12-05 Mirko Wilde , Mareike Fischer

In this perspective article, we present a multidisciplinary approach for characterizing protein structure networks. We first place our approach in its historical context and describe the manner in which it synthesizes concepts from quantum…

Molecular Networks · Quantitative Biology 2019-12-30 Vasundhara Gadiyaram , Smitha Vishveshwara , Saraswathi Vishveshwara

Compound graphs are networks in which vertices can be grouped into larger subsets, with these subsets capable of further grouping, resulting in a nesting that can be many levels deep. In several applications, including biological workflows,…

Human-Computer Interaction · Computer Science 2024-08-09 Chang Han , Justin Lieffers , Clayton Morrison , Katherine E. Isaacs

Several authors modelled networks ad hoc by oriented or disoriented graphs, whereby the problem of allowance (allocation) of the frequencies at the level of the network was transformed into coloring problem of nodes in the graph. Graph…

Discrete Mathematics · Computer Science 2014-06-06 Ali Mansouri , Mohamed Salim Bouhlel

Biological networks provide insight into the complex organization of biological processes in a cell at the system level. They are an effective tool for understanding the comprehensive map of functional interactions, finding the functional…

Molecular Networks · Quantitative Biology 2017-09-14 Somaye Hashemifar