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This paper concerns multiphase models of tumor growth in interaction with a surrounding tissue, taking into account also the interplay with diffusible nutrients feeding the cells. Models specialize in nonlinear systems of possibly…

Mathematical Physics · Physics 2017-01-20 Andrea Tosin

Prototyping is an important part in research and development of tangible user interfaces (TUIs). On the way from the idea to a working prototype, new hardware prototypes usually have to be crafted repeatedly in numerous iterations. This…

Human-Computer Interaction · Computer Science 2014-06-03 Stefan Diewald , Andreas Möller , Luis Roalter , Matthias Kranz

It is difficult or infeasible to directly measure how much of a drug actually enters the human brain and a brain tumor, how long it remains there, and to estimate drug-specific or patient-specific parameters, as well as how changes in these…

Dynamical Systems · Mathematics 2026-03-13 Charuka D. Wickramasinghe , Nelum S. S. M. Hapuhinna

Computer-Aided Diagnosis and Treatment of Tumors is a hot topic of deep learning in recent years, which constitutes a series of medical tasks, such as detection of tumor markers, the outline of tumor leisures, subtypes and stages of tumors,…

Image and Video Processing · Electrical Eng. & Systems 2020-11-03 Dan Zhao , Guizhi Xu , Zhenghua XU , Thomas Lukasiewicz , Minmin Xue , Zhigang Fu

The problem of the onset and growth of solid tumour in homogeneous tissue is regarded using an approach based on local interaction between the tumoral and the sane tissue cells. The characteristic sizes and growth rates of spherical…

Cell Behavior · Quantitative Biology 2007-05-23 R. G. Khlebopros , V. A. Slepkov , V. G. Sukhovolsky , Y. V. Mironov , V. E. Fedorov , S. P. Gabuda

The aim of this chapter is to provide a brief introduction into the basics of a top-down multilevel tumor dynamics modeling method primarily based on discrete entity consideration and manipulation. The method is clinically oriented, one of…

Medical Physics · Physics 2010-09-14 Georgios Stamatakos

In this note we present a computational approach to the construction of ovoids of the Hermitian surface and show some related experimental results.

Combinatorics · Mathematics 2012-10-10 Luca Giuzzi

Numerical simulation of quantum systems is crucial to further our understanding of natural phenomena. Many systems of key interest and importance, in areas such as superconducting materials and quantum chemistry, are thought to be described…

Quantum Physics · Physics 2010-11-17 Katherine L Brown , William J Munro , Vivien M Kendon

Brain tumor segmentation is one of the most challenging problems in medical image analysis. The goal of brain tumor segmentation is to generate accurate delineation of brain tumor regions. In recent years, deep learning methods have shown…

Image and Video Processing · Electrical Eng. & Systems 2021-11-18 Zhihua Liu , Lei Tong , Zheheng Jiang , Long Chen , Feixiang Zhou , Qianni Zhang , Xiangrong Zhang , Yaochu Jin , Huiyu Zhou

In this work we present a flexible tool for tumor progression, which simulates the evolutionary dynamics of cancer. Tumor progression implements a multi-type branching process where the key parameters are the fitness landscape, the mutation…

Populations and Evolution · Quantitative Biology 2013-03-22 Johannes G. Reiter , Ivana Bozic , Krishnendu Chatterjee , Martin A. Nowak

Owing to the computational complexity of electronic structure algorithms running on classical digital computers, the range of molecular systems amenable to simulation remains tightly circumscribed even after many decades of work. Quantum…

Quantum Physics · Physics 2022-05-18 Alexis Ralli , Michael I. Williams , Peter V. Coveney

Tumor saliency estimation aims to localize tumors by modeling the visual stimuli in medical images. However, it is a challenging task for breast ultrasound due to the complicated anatomic structure of the breast and poor image quality; and…

Computer Vision and Pattern Recognition · Computer Science 2019-06-20 Fei Xu , Yingtao Zhang , Min Xian , H. D. Cheng , Boyu Zhang , Jianrui Ding , Chunping Ning , Ying Wang

The segmentation of brain tumors in multimodal MRIs is one of the most challenging tasks in medical image analysis. The recent state of the art algorithms solving this task is based on machine learning approaches and deep learning in…

Image and Video Processing · Electrical Eng. & Systems 2020-02-11 Dmitrii Lachinov , Elena Shipunova , Vadim Turlapov

Computer simulations that demonstrate the valueof novel approaches are crucial to developing more flexibleand robust power systems operations with high penetrations ofrenewable energy at multiple geographic and temporal scales.However,…

Systems and Control · Electrical Eng. & Systems 2020-09-01 Jose Daniel Lara , Jonathan T. Lee , Duncan Callaway , Bri-Mathias Hodge

Cancer research has shifted from a purely gene-centric view to a more holistic understanding that recognizes the critical role of the tumour microenvironment, where mechanics and metabolism are key drivers of disease progression. However,…

Computational Engineering, Finance, and Science · Computer Science 2025-12-19 Pedro Garcia-Gomez , Paula Guerrero-Lopez , Silvia Hervas-Raluy , Jose Manuel Garcia-Aznar

Initiation and development of a malignant tumor is a complex phenomenon that has critical stages determining its long time behavior. This phenomenon is mathematically described by means of various models: from simple heuristic models to…

Populations and Evolution · Quantitative Biology 2020-03-23 Yuri Kozitsky , Krzysztof Pilorz

Inflammatory breast cancer (IBC), a rare form of breast cancer associated with increased angiogenesis and metastasis, is largely driven by tumor-stromal interactions with the vasculature and the extracellular matrix (ECM). However, there is…

Tumour invasion is strongly influenced by microenvironment and, among other parameters, chemical stimuli play an important role. An innovative methodology for the quantitative investigation of chemotaxis in vitro by live imaging of…

Cell Behavior · Quantitative Biology 2022-03-29 Rosalia Ferraro , Flora Ascione , Prashant Dogra , Vittorio Cristini , Stefano Guido , Sergio Caserta

Accurate simulations of vibrational molecular spectra are expensive on conventional computers. Compared to the electronic structure problem, the vibrational structure problem with quantum computers is less investigated. In this work we…

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