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The NF-kB signalling system is involved in a variety of cellular processes including immune response, inflammation, and apoptosis. Recent experiments have found oscillations in the nuclear-cytoplasmic translocation of the NF-kB…
The NF-{\kappa}B signaling network plays an important role in many different compartments of the immune system during immune activation. Using a computational model of the NF-{\kappa}B signaling network involving two negative regulators,…
NF-{\kappa}B is a pleiotropic protein whose nucleo-cytoplasmic trafficking is tightly regulated by multiple negative feedback loops embedded in the NF-{\kappa}B signaling network and contributes to diverse gene expression profiles important…
NF-kB is a major transcription factor mediating inflammatory response. In response to pro-inflammatory stimulus, it exhibits characteristic response -- a pulse followed by noisy oscillations in concentrations of considerably smaller…
Inflammatory responses in eucaryotic cells are often associated with oscillations in the nuclear-cytoplasmic translocation of the transcription factor NF-kB. In most laboratory realizations, the oscillations are triggered by a cytokine…
Organisms are equipped with regulatory systems that display a variety of dynamical behaviours ranging from simple stable steady states, to switching and multistability, to oscillations. Earlier work has shown that oscillations in protein…
Oscillatory chemical reactions often serve as a timing clock of cellular processes in living cells. The temporal dynamics of protein concentration levels is thus of great interest in biology. Here we propose a theoretical framework to…
NF-{\kappa}B, one of key regulators of inflammation, apoptosis, and differentiation, was found to have noisy oscillatory shuttling between the nucleus and the cytoplasm in single cells when cells are stimulated by cytokine TNF{\alpha}. We…
Since the first recordings made of evoked action potentials it has become apparent that the responses of individual neurons to ongoing physiologically relevant input, are highly variable. This variability is manifested in non-stationary…
Coherent time-delayed feedback allows the control of a quantum system and its partial stabilization against noise and decoherence. The crucial and externally accessible parameters in such control setups are the round-trip-induced delay time…
We show that it is possible to modify the stationary state by a feedback control in a two-level dissipative quantum system. Based on the geometric control theory, we also analyze the effect of the feedback on the time-optimal control in the…
We have observed millisecond-long coherent evolution of nuclear spins in a quantum wire at 1.2 K. Local, all-electrical manipulation of nuclear spins is achieved by dynamic nuclear polarization in the breakdown regime of the Integer Quantum…
The development of new techniques to quantitatively measure gene expression in cells has shed light on a number of systems that display oscillations in protein concentration. Here we review the different mechanisms which can produce…
We have studied theoretically the basic operation of a quantum feedback loop designed to maintain a desired phase of quantum coherent oscillations in a single solid-state qubit. The degree of oscillations synchronization with external…
We consider the effect of asymmetric temporal delays in a system of two coupled Hopfield neurons. For couplings of opposite signs, a limit cycle emerges via a supercritical Hopf bifurcation when the sum of the delays reaches a critical…
We investigate the real-time closed-loop control of compensation point in the K-Rb-$^{21}$Ne comagnetometer operated in the spin-exchange relaxation-free regime. By locking the electron resonance, the alkali metal electrons are free from…
An inhomogeneous transport current, which is introduced through multiple electrodes in an open Nb microtube, is shown to lead to a controllable branching of the vortex nucleation period. The detailed mechanism of this branching is analyzed…
We calculate the magnetisation relaxation in the short-time regime for an ensemble of nanomagnets in the presence of a low-frequency external AC biasing field, at temperatures lower than the magnetic anisotropy energy of the individual…
A spatial-time method of description of alpha-decay of a nucleus is presented. The method is based on the quantum mechanical model of the alpha-decay of a compound nuclear system with the barrier. alpha-decay dynamics is described on the…
We study the oscillatory behaviour of a gene regulatory network with interlinked positive and negative feedback loop. Frequency and amplitude are two important properties of oscillation. Studied network produces two different modes of…