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The physical interpretation of the functioning of the adaptive immune system, which has been thoroughly characterized on genetic and molecular levels, provides a unique opportunity to define an adaptive self-organizing biological system in…

Molecular Networks · Quantitative Biology 2023-05-19 Jozsef Prechl

AI agents are increasingly deployed as quasi-autonomous systems for specialized tasks, yet their potential as computational models of decision-making remains underexplored. We develop a generative AI agent to study repetitive policy…

Multiagent Systems · Computer Science 2026-01-09 Goshi Aoki , Navid Ghaffarzadegan

There is a need for new metaphors from immunology to flourish the application areas of Artificial Immune Systems. A metaheuristic called Obesity Heuristic derived from advances in obesity treatment is proposed. The main forces of the…

Artificial Intelligence · Computer Science 2013-01-15 Mohammed El-Dosuky , Ahmed EL-Bassiouny , Taher Hamza , Magdy Rashad

Many optimization problems in science and engineering are challenging to solve, and the current trend is to use swarm intelligence (SI) and SI-based algorithms to tackle such challenging problems. Some significant developments have been…

Neural and Evolutionary Computing · Computer Science 2018-04-24 Xin-She Yang , Suash Deb , Yuxin Zhao , Simon Fong , Xingshi He

We present a time complexity analysis of the Opt-IA artificial immune system (AIS). We first highlight the power and limitations of its distinguishing operators (i.e., hypermutations with mutation potential and ageing) by analysing them in…

Neural and Evolutionary Computing · Computer Science 2019-03-18 Dogan Corus , Pietro S. Oliveto , Donya Yazdani

An artificial Ant Colony System (ACS) algorithm to solve general-purpose combinatorial Optimization Problems (COP) that extends previous AC models [21] by the inclusion of a negative pheromone, is here described. Several Travelling Salesman…

Neural and Evolutionary Computing · Computer Science 2013-06-14 Vitorino Ramos , David M. S. Rodrigues , Jorge Louçã

The coming 5G networks have been enabling the creation of a wide variety of new services and applications which demand a new network security architecture. Immunology is the study of the immune system in vertebrates (including humans) which…

Cryptography and Security · Computer Science 2020-01-28 Quan Yu , Jing Ren , Jiyan Zhang , Siyang Liu , Yinjin Fu , Ying Li , Linru Ma , Jian Jing , Wei Zhang

Immune cells coordinate their efforts for the correct and efficient functioning of the immune system (IS). Each cell type plays a distinct role and communicates with other cell types through mediators such as cytokines, chemokines and…

Molecular Networks · Quantitative Biology 2007-05-23 Paolo Tieri , Silvana Valensin , Vito Latora , Gastone C. Castellani , Massimo Marchiori , Daniel Remondini , Claudio Franceschi

The mechanisms by which organs acquire their functional structure and realize its maintenance (or homeostasis) over time are still largely unknown. In this paper, we investigate this question on adipose tissue. Adipose tissue can represent…

In modern deep neural networks, the learning dynamics of the individual neurons is often obscure, as the networks are trained via global optimization. Conversely, biological systems build on self-organized, local learning, achieving…

Over the last decade, a new idea challenging the classical self-non-self viewpoint has become popular amongst immunologists. It is called the Danger Theory. In this conceptual paper, we look at this theory from the perspective of Artificial…

Neural and Evolutionary Computing · Computer Science 2010-07-05 Uwe Aickelin , Steve Cayzer

The rise of autonomous AI agents in enterprise and industrial environments introduces a critical challenge: how to securely assign, verify, and manage their identities across distributed systems. Existing identity frameworks based on API…

Cryptography and Security · Computer Science 2025-04-24 Sebastian Barros

We propose a Parton Distribution Function (PDF) fitting technique which is based on an interactive neural network algorithm using Self-Organizing Maps (SOMs). SOMs are visualization algorithms based on competitive learning among…

High Energy Physics - Phenomenology · Physics 2016-04-26 H. Honkanen , S. Liuti

Our main purpose is to compare classical nonself-centered, two-signal theoretical models of the adaptive immune system with a novel, self-centered, one-signal model developed by our research group. Our model hypothesizes that the immune…

Molecular Networks · Quantitative Biology 2020-12-02 Tamás Szabados , Csaba Kerepesi , Tibor Bakács

Foundation models, a cornerstone of recent advancements in machine learning, have predominantly thrived on complete and well-structured data. Wearable sensor data frequently suffers from significant missingness, posing a substantial…

The development of artificial intelligence (AI) and robotics are both based on the tenet of "science and technology are people-oriented", and both need to achieve efficient communication with the human brain. Based on multi-disciplinary…

Neurons and Cognition · Quantitative Biology 2024-06-27 Shengjie Zheng , Ling Liu , Junjie Yang , Jianwei Zhang , Tao Su , Bin Yue , Xiaojian Li

This paper presents the self-organized neuromorphic architecture named SOMA. The objective is to study neural-based self-organization in computing systems and to prove the feasibility of a self-organizing hardware structure. Considering…

Neural and Evolutionary Computing · Computer Science 2018-10-31 Lyes Khacef , Bernard Girau , Nicolas Rougier , Andres Upegui , Benoit Miramond

UASs form a large part of the fighting ability of the advanced military forces. In particular, these systems that carry confidential information are subject to security attacks. Accordingly, an Intrusion Detection System (IDS) has been…

Cryptography and Security · Computer Science 2020-03-12 Reza Fotohi

This paper shows how to use the Kohonen algorithm to represent multidimensional data, by exploiting the self-organizing property. It is possible to get such maps as well for quantitative variables as for qualitative ones, or for a mixing of…

Statistics Theory · Mathematics 2016-08-16 Marie Cottrell , SmaÏl Ibbou , Patrick Letrémy , Patrick Rousset

Some years ago a cellular automata model was proposed to describe the evolution of the immune repertoire of B cells and antibodies based on Jerne's immune network theory and shape-space formalism. Here we investigate if the networks…

Biological Physics · Physics 2012-01-31 Hallan Souza-e-Silva , Rita Maria Zorzenon dos Santos