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Thermophilic enzymes can operate at higher temperatures but show reduced activities at room temperature. They are in general more stable during preparation and, accordingly, are considered to be more rigid in structure. Crystallization is…

Biomolecules · Quantitative Biology 2015-06-04 Eva Hammann , Andrea Zappe , Stefanie Keis , Stefan Ernst , Doreen Matthies , Thomas Meier , Gregory M. Cook , Michael Boersch

We study a synthetic system of motile Escherichia coli bacteria encapsulated inside giant lipid vesicles. Forces exerted by the bacteria on the inner side of the membrane are sufficient to extrude membrane tubes filled with one or several…

The transport of molecules through biological and synthetic nanopores is governed by multiple stochastic processes that lead to noisy, fluctuating currents. Disentangling the characteristics of different noise-generating mechanisms is…

Soft Condensed Matter · Physics 2024-10-03 Stuart F. Knowles , Eleanor K. R. Mackay , Alice L. Thorneywork

We use molecular dynamics simulations to study the behavior of supercooled water subject to different stimuli from a diluted azobenzene hydrophobic probe. When the molecular motor does not fold, it acts as a passive probe, modifying the…

Soft Condensed Matter · Physics 2020-01-14 V. Teboul , G. Rajonson

Numerous natural systems depend on the sedimentation of passive particles in presence of swimming microorganisms. Here, we investigate the dynamics of the sedimentation of spherical colloids at various E. coli concentration within the…

Motivated by the aim of understanding the effect of media heterogeneity on the swimming dynamics of flagellated bacteria, we study the rotation and swimming of rigid helices in dilute suspensions experimentally and theoretically. We first…

Fluid Dynamics · Physics 2024-11-27 Albane Théry , Andres Zambrano , Eric Lauga , Roberto Zenit

In bacterial chemotaxis, E. coli cells drift up chemical gradients by a series of runs and tumbles. Runs are periods of directed swimming, and tumbles are abrupt changes in swimming direction. Near the beginning of each run, the rotating…

Soft Condensed Matter · Physics 2009-11-07 Thomas R. Powers

Helical propulsion is used by many microorganisms to swim in viscous-dominated environments. Their swimming dynamics are relatively well understood, but detailed study of the flow fields and actuation mechanisms are still needed to realize…

Soft Condensed Matter · Physics 2022-04-27 Asimanshu Das , Matthew Styslinger , Daniel M. Harris , Roberto Zenit

Run-and-tumble is a basic model of persistent motion and a motility strategy widespread in micro-organisms and individual cells. In many natural settings, movement occurs in the presence of confinement. While accumulation at the surface has…

Soft Condensed Matter · Physics 2024-04-12 T. Pietrangeli , C. Ybert , C. Cottin-Bizonne , F. Detcheverry

The presence of a nearby boundary is likely to be important in the life cycle and evolution of motile flagellate bacteria. This has led many authors to employ numerical simulations to model near-surface bacterial motion and compute…

Biological Physics · Physics 2021-09-21 Orrin Shindell , Hoa Nguyen , Nicholas Coltharp , Frank Healy , Bruce Rodenborn

As a paradigmatic model of active fluids, bacterial suspensions show intriguing rheological responses drastically different from their counterpart colloidal suspensions. Although the flow of bulk bacterial suspensions has been extensively…

Soft Condensed Matter · Physics 2019-06-11 Zhengyang Liu , Kechun Zhang , Xiang Cheng

The transport of an infinitely thin, hard rod in a random, dense array of point obstacles is investigated by molecular dynamics simulations. Our model mimics the sterically hindered dynamics in dense needle liquids. The center-of-mass…

Statistical Mechanics · Physics 2008-09-22 Felix Höfling , Erwin Frey , Thomas Franosch

We consider a heat conduction model introduced in \cite{Collet-Eckmann 2009}. This is an open system in which particles exchange momentum with a row of (fixed) scatterers. We assume simplified bath conditions throughout, and give a…

Chaotic Dynamics · Physics 2015-05-19 Jean-Pierre Eckmann , Lai-Sang Young

We show that the flagellar beat of bull spermatozoa and Chlamydomonas Reinhardtii can be modelled by a minimal, geometrically nonlinear reaction-diffusion system. Model solutions are spatio-temporally animated patterns describing flagellar…

Biological Physics · Physics 2023-10-09 James F. Cass , Hermes Bloomfield-Gadelha

Recent experiments reveal both passive subdiffusion of various nanoparticles and anomalous active transport of such particles by molecular motors in the molecularly crowded environment of living biological cells. Passive and active…

Biological Physics · Physics 2014-03-24 Igor Goychuk , Vasyl O. Kharchenko , R. Metzler

We study diffusion properties of an inertial Brownian motor moving on a ratchet substrate, i.e. a periodic structure with broken reflection symmetry. The motor is driven by an unbiased time-periodic symmetric force which takes the system…

Statistical Mechanics · Physics 2021-03-25 Jakub Spiechowicz , Marcin Kostur , Jerzy Łuczka

Single-molecule experiments have found near-perfect thermodynamic efficiency in the rotary motor F1-ATP synthase. To help elucidate the principles underlying nonequilibrium energetic efficiency in such stochastic machines, we investigate…

Statistical Mechanics · Physics 2019-09-05 Joseph N. E. Lucero , Aliakbar Mehdizadeh , David A. Sivak

In the present work we simulate the basic two-dimensional dynamics of swarming E. coli bacteria on the surface of a moderately soft agar plate. Individual bacteria are modelled by self-propelled ridged bodies (agents), which interact with…

Soft Condensed Matter · Physics 2016-12-31 David Hansmann , Guido Fier , Rubén Carlos Buceta

We investigate the dynamics of a pair of rigid rotating helices in a viscous fluid, as a model for bacterial flagellar bundle and a prototype of microfluidic pumps. Combining experiments with hydrodynamic modeling, we examine how spacing…

Fluid Dynamics · Physics 2025-05-13 Chijing Zang , Luke Omodt , Moumita Dasgupta , Xiang Cheng

Peritrichous bacteria such as Escherichia coli swim in viscous fluids by forming a helical bundle of flagellar filaments. The filaments are spatially distributed around the cell body to which they are connected via a flexible hook. To…

Biological Physics · Physics 2019-06-19 Kenta Ishimoto , Eric Lauga