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The purpose of this article is twofold. On one hand, we reveal the equivalence of shift of finite type between a one-sided shift $X$ and its associated hom tree-shift $\mathcal{T}_{X}$, as well as the equivalence in the sofic shift. On the…

Dynamical Systems · Mathematics 2021-08-31 Jung-Chao Ban , Chih-Hung Chang , Wen-Guei Hu , Guan-Yu Lai , Yu-Liang Wu

The concepts of orthology, paralogy, and xenology play a key role in molecular evolution. Orthology and paralogy distinguish whether a pair of genes originated by speciation or duplication. The corresponding binary relations on a set of…

Discrete Mathematics · Computer Science 2016-03-09 Marc Hellmuth , Peter F. Stadler , Nicolas Wieseke

Reconstructing the tree of life from molecular sequences is a fundamental problem in computational biology. Modern data sets often contain a large number of genes, which can complicate the reconstruction problem due to the fact that…

Probability · Mathematics 2017-07-21 Constantinos Daskalakis , Sebastien Roch

Reticulate evolutionary processes result in phylogenetic histories that cannot be modeled using a tree topology. Here, we apply methods from topological data analysis to molecular sequence data with reticulations. Using a simple example, we…

Quantitative Methods · Quantitative Biology 2015-11-05 Kevin Emmett , Raul Rabadan

Phylogenetic networks are increasingly used in evolutionary biology to represent the history of species that have undergone reticulate events such as horizontal gene transfer, hybrid speciation and recombination. One of the most fundamental…

Populations and Evolution · Quantitative Biology 2016-10-07 Philippe Gambette , Leo van Iersel , Steven Kelk , Fabio Pardi , Celine Scornavacca

Phylogenetically decisive collections of taxon sets have the property that if trees are chosen for each of their elements, as long as these trees are compatible, the resulting supertree is unique. This means that as long as the trees…

Populations and Evolution · Quantitative Biology 2025-05-29 Mareike Fischer , Janne Pott

Deep Generative Models (DGMs) are versatile tools for learning data representations while adequately incorporating domain knowledge such as the specification of conditional probability distributions. Recently proposed DGMs tackle the…

Machine Learning · Computer Science 2024-01-30 Romain Lopez , Jan-Christian Huetter , Ehsan Hajiramezanali , Jonathan Pritchard , Aviv Regev

Phylogenetics uses alignments of molecular sequence data to learn about evolutionary trees. Substitutions in sequences are modelled through a continuous-time Markov process, characterised by an instantaneous rate matrix, which standard…

Populations and Evolution · Quantitative Biology 2020-07-20 Naomi E. Hannaford , Sarah E. Heaps , Tom M. W. Nye , Tom A. Williams , T. Martin Embley

Linear mixture models have proven very useful in a plethora of applications, e.g., topic modeling, clustering, and source separation. As a critical aspect of the linear mixture models, identifiability of the model parameters is…

Machine Learning · Computer Science 2021-02-24 Bo Yang , Xiao Fu , Nicholas D. Sidiropoulos , Kejun Huang

Pedigrees are directed acyclic graphs that represent ancestral relationships between individuals in a population. Based on a schematic recombination process, we describe two simple Markov models for sequences evolving on pedigrees - Model R…

Populations and Evolution · Quantitative Biology 2013-01-18 Bhalchandra D. Thatte

We analyse the statistical properties of genealogical trees in a neutral model of a closed population with sexual reproduction and non-overlapping generations. By reconstructing the genealogy of an individual from the population evolution,…

Condensed Matter · Physics 2009-10-31 Bernard Derrida , Susanna C. Manrubia , Damian H. Zanette

Bipartite networks provide an effective resource for representing, characterizing, and modeling several abstract and real-world systems and structures involving binary relations, which include food webs, social interactions, and…

Social and Information Networks · Computer Science 2024-02-01 Alexandre Benatti , Luciano da F. Costa

The problem of identifiability of finite mixtures of finite product measures is studied. A mixture model with $K$ mixture components and $L$ observed variables is considered, where each variable takes its value in a finite set with…

Statistics Theory · Mathematics 2018-07-17 Behrooz Tahmasebi , Seyed Abolfazl Motahari , Mohammad Ali Maddah-Ali

Machine learning (ML) and deep learning models are extensively used for parameter optimization and regression problems. However, not all inverse problems in ML are ``identifiable,'' indicating that model parameters may not be uniquely…

Machine Learning · Computer Science 2023-07-24 Reza Sameni

Model performance is frequently reported only for the overall population under consideration. However, due to heterogeneity, overall performance measures often do not accurately represent model performance within specific subgroups. We…

Methodology · Statistics 2025-06-03 Ruotao Zhang , Constantine Gatsonis , Jon Steingrimsson

A large class of phylogenetic networks can be obtained from trees by the addition of horizontal edges between the tree edges. These networks are called tree based networks. Reticulation-visible networks and child-sibling networks are all…

Populations and Evolution · Quantitative Biology 2015-09-09 Louxin Zhang

In evolutionary biology, phylogenetic trees are commonly inferred from a set of characters (partitions) of a collection of biological entities (e.g., species or individuals in a population). Such characters naturally arise from molecular…

Populations and Evolution · Quantitative Biology 2023-11-17 Katharina T. Huber , Simone Linz , Vincent Moulton , Charles Semple

We establish a log-supermodularity property for probability distributions on binary patterns observed at the tips of a tree that are generated under any 2--state Markov process. We illustrate the applicability of this result in…

Populations and Evolution · Quantitative Biology 2008-05-21 Mike Steel , Beata Faller

This paper addresses the problem of identifying the graph structure of a dynamical network using measured input/output data. This problem is known as topology identification and has received considerable attention in recent literature. Most…

Optimization and Control · Mathematics 2020-05-08 Henk J. van Waarde , Pietro Tesi , M. Kanat Camlibel

We consider a two-parameter family of random substitutions and show certain combinatorial and topological properties they satisfy. We establish that they admit recognisable words at every level. As a consequence, we get that the subshifts…

Dynamical Systems · Mathematics 2021-08-13 Giovanni B. Escolano , Neil Mañibo , Eden Delight Miro