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Structural information of phylogenetic tree topologies plays an important role in phylogenetic inference. However, finding appropriate topological structures for specific phylogenetic inference tasks often requires significant design effort…

Machine Learning · Statistics 2023-02-20 Cheng Zhang

Phylogenetic networks are a type of directed acyclic graph that represent how a set $X$ of present-day species are descended from a common ancestor by processes of speciation and reticulate evolution. In the absence of reticulate evolution,…

Combinatorics · Mathematics 2017-08-11 Andrew Francis , Charles Semple , Mike Steel

Mixture models have been widely used in modeling of continuous observations. For the possibility to estimate the parameters of a mixture model consistently on the basis of observations from the mixture, identifiability is a necessary…

Probability · Mathematics 2014-07-02 ZiQiang Shi , TieRan Zheng , JiQing Han

We propose a statistical method to test whether two phylogenetic trees with given alignments are significantly incongruent. Our method compares the two distributions of phylogenetic trees given by the input alignments, instead of comparing…

Populations and Evolution · Quantitative Biology 2010-04-14 Elissaveta Arnaoudova , David Haws , Peter Huggins , Jerzy W. Jaromczyk , Neil Moore , Chris Schardl , Ruriko Yoshida

Upon a matrix representation of a binary bipartite network, via the permutation invariance, a coupling geometry is computed to approximate the minimum energy macrostate of a network's system. Such a macrostate is supposed to constitute the…

Applications · Statistics 2018-02-02 Jiahui Guan , Hsieh Fushing

Complex dynamical systems are often modeled as networks, with nodes representing dynamical units which interact through the network's links. Gene regulatory networks, responsible for the production of proteins inside a cell, are an example…

Statistical Mechanics · Physics 2009-09-30 Zoran Levnajić

Background: Tree reconciliation problems have long been studied in phylogenetics. A particular variant of the reconciliation problem for a gene tree T and a species tree S assumes that for each interior vertex x of T it is known whether x…

Discrete Mathematics · Computer Science 2017-05-12 Maribel Hernandez-Rosales , Marc Hellmuth , Nicolas Wieseke , Katharina T. Huber , Vincent Moulton , Peter F. Stadler

Given two messages - as linear sequences of letters, it is immediate to determine whether one can be transformed into the other by simple substitution cipher of the letters. On the other hand, if the letters are carried as labels on nodes…

Discrete Mathematics · Computer Science 2022-04-14 Florian Ingels , Romain Azaïs

Phylogenetic networks generalize phylogenetic trees, and have been introduced in order to describe evolution in the case of transfer of genetic material between coexisting species. There are many classes of phylogenetic networks, which can…

Combinatorics · Mathematics 2020-03-13 Mathilde Bouvel , Philippe Gambette , Marefatollah Mansouri

The history of gene families - which are equivalent to \emph{event-labeled} gene trees - can be reconstructed from empirically estimated evolutionary event-relations containing pairs of orthologous, paralogous or xenologous genes. The…

Discrete Mathematics · Computer Science 2017-06-13 Marc Hellmuth

Binary trait data record the presence or absence of distinguishing traits in individuals. We treat the problem of estimating ancestral trees with time depth from binary trait data. Simple analysis of such data is problematic. Each homology…

Methodology · Statistics 2009-08-31 Geoff K. Nicholls , Russell D. Gray

Predicting the ancestral sequences of a group of homologous sequences related by a phylogenetic tree has been the subject of many studies, and numerous methods have been proposed to this purpose. Theoretical results are available that show…

Populations and Evolution · Quantitative Biology 2013-09-05 Olivier Gascuel , Mike Steel

Species richness varies widely across the tree of life, and there is great interest in identifying ecological, geographic, and other factors that affect rates of species proliferation. Recent methods for explicitly modeling the…

Populations and Evolution · Quantitative Biology 2014-12-23 Daniel L. Rabosky , Emma E. Goldberg

Linear compartmental models are a widely used tool for analyzing systems arising in biology, medicine, and more. In such settings, it is essential to know whether model parameters can be recovered from experimental data. This is the…

Combinatorics · Mathematics 2025-11-18 Katherine Clemens , Jonathan Martinez , Anne Shiu , Michaela Thompson , Benjamin Warren

If model identifiability is not confirmed, inferences from infectious disease transmission models may not be reliable, so they might lead to misleading recommendations. Structural identifiability analysis characterizes whether it is…

Quantitative Methods · Quantitative Biology 2022-06-09 Emmanuelle A. Dankwa , Andrew F. Brouwer , Christl A. Donnelly

Phylogenetic trees are often constructed by using a metric on the set of taxa that label the leaves of the tree. While there are a number of methods for constructing a tree using a given metric, such trees will only display the metric if it…

Populations and Evolution · Quantitative Biology 2019-08-26 Michael Hendriksen , Andrew Francis

Understanding the evolutionary relationship among species is of fundamental importance to the biological sciences. The location of the root in any phylogenetic tree is critical as it gives an order to evolutionary events. None of the…

Populations and Evolution · Quantitative Biology 2016-11-15 Benjamin D Kaehler

A matching complex of a simple graph $G$ is a simplicial complex with faces given by the matchings of $G$. The topology of matching complexes is mysterious; there are few graphs for which the homotopy type is known. Marietti and Testa…

Combinatorics · Mathematics 2021-02-01 Marija Jelić Milutinović , Helen Jenne , Alex McDonough , Julianne Vega

Interest in the inference of evolutionary networks relating species or populations has grown with the increasing recognition of the importance of hybridization, gene flow and admixture, and the availability of large-scale genomic data.…

Populations and Evolution · Quantitative Biology 2024-07-23 John A. Rhodes , Hector Banos , Jingcheng Xu , Cécile Ané

Compatibility of unrooted phylogenetic trees is a well studied problem in phylogenetics. It asks to determine whether for a set of k input trees there exists a larger tree (called a supertree) that contains the topologies of all k input…

Discrete Mathematics · Computer Science 2014-03-03 Alexander Grigoriev , Steven Kelk , Nela Lekic
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